This document discusses managing hypoglycemia and hyperglycemia in the intensive care unit. It provides guidelines for tight glycemic control to decrease between 80-110 mg/dL. Hypoglycemia is treated with orange juice, glucagon, or dextrose IV depending on the severity of symptoms. Hyperglycemia is initially treated with a sliding scale regular insulin but severe cases over 400 mg/dL may require a continuous insulin drip to control blood glucose levels closely. Frequent monitoring of blood glucose and patient assessment is important.