1. Lymphomas are cancers that affect lymphocytes, a type of white blood cell, and usually start in lymph nodes but can spread to other lymphatic tissues. 2. There are two main categories of lymphoma - Hodgkin lymphoma and non-Hodgkin lymphoma. The main difference is the presence of Reed-Sternberg cells in Hodgkin lymphoma. 3. Common symptoms of lymphoma include painless swelling of lymph nodes, unexplained fever, weight loss, night sweats, and fatigue. Diagnosis involves physical exam, biopsy of lymph nodes, and other tests. Treatment depends on the type, stage, and other factors but may include chemotherapy, radiation therapy, immunotherapy, or stem cell transplant.