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LIVER ABCESS
PREPARED BY – NUPUR VASHISHT
SUBMMITED TO-MRS. NIDHI
JOSEPH
ANAOMY AND
PHYSIOLOGY
OF LIVER
LIVER
PHYSIOLOGY• STORAGE OF GLYCOGEN , AMINO ACID AND VITAMIN B12
• SYNTHESIS OF GLUCOSE BY GLUCONEOGENESIS
• SECRETION OF BILE
• EXCRETION OF CHOLESTROL AND BILE PIGMENTS
• DEFENCE OF BODY BY KUPFFER CELLS
• HEMATOPOEISIS IN FETUS
• DESTRUCTION OF OLD RBC
• METABOLISM OF PROTEIN , FATS AND CARBOHYDRATE
INTRODUCTION
TO LIVER ABCESS
INTRODUCTION
A LOCALIZED INFECTION IN THE LIVER PARECNCHYMA
THAT MAY BE BACTERIAL , FUNGAL , PARASITIC IN
ORIGIN .
APPENDICITIS WITH RUPTURE AND SUBSEQUENT
SPREAD OF INFECTION WAS THE MOST COMMON
CAUSE OF LIVER ABCESS .
DEFINITION
•LIVER ABSCESS ARE PURULENT
COLLECTION IN THE LIVER
PARENCHYMA THAT RESULT FROM
BACTERIAL . FUNGAL , OR
PARASITIC INFECTION IN WHICH
A MASS FILLED WITH PUS IS
PRESENT INSIDE THE LIVER .
TYPES OF LIVER
ABSCESS
PYOGENIC
ABSCESS
WHICH IS MOST OFTEN
POLYMICROBIAL AND
MOSTLY ACCOUNT FOR
80% OF HEPATIC ABSCESS
IN US . INTESTINAL
MICROBES SUCH AS
E.COLLI ,
STREPTOCOCCUS , AND
STAPHYLOCOCCUS .
AMOEBIC
ABSCESS
DUE TO ENTAMOBA
HISTOLYTICA ACCOUNT
FOR 10 % OF CASES .ITS
MOSTLY OCCURING IN
THE DEVELOPING
COUNTRIES OF TROPICS
BECAUSE OF POOR
SANITATION AND
HYGIENE .
FUNGAL
ABSCESS
MOST OFTEN DUE TO
CANDIDA SPECIES ,
ACCOUNT FOR LESS
THAN 10 % OF CASES.
MOSQUITO AND
NEUTROPENIA
FACILITATES THE SPREAD
OF ABSCESS FROM GI
TRACT TO THE LIVER .
PATHOPHYSIOLOGY
PATHOPHYSIOLOGY• INFECTION DEVELOP ANYWHERE ALONG THE BILIARY TRACT OR GI TRACT
• INFECTING ORGANISM REACH LIVER THROUGH BILIARY CIRCULATION , HEPATIC
ARTERIES
• BACTERIA DESTROY NEIGHBOURING LIVER CELLS AND RESULT IN NECROSIS AND
SERVE AS A PROTECTIVE WALL FOR THE ORGANISM
• MEANWHILE LEUKOCYTES MIGRATE INTO THE INFECTED AREA
CONTINUE…..• RESULTS IN LIVER ABSCESS ,CAVITY FULL OF A LIQUID CONTAINING LIVING AND
DEAD LEAUKOCYTES , LIQUIFIED LIVER CELLS AND BACTERIA
CAUSES OF LIVER
ABSCESS
BACTERIAL
CAUSES
A. STREPTOCOCCUS
B. ESCHERICHIA SPECIES
C. STAPHYLOCCUS
D. KLEBSIELLA
E. ENTAMOEBA
HISTOLYTICA
F. CANDIDA SPECIES
POSSIBLE CAUSES
ABDOMINAL INFECTION SUCH AS APPENDICITIS , DIVERTICULITIS
INFECTION OF BILE DRAINING TUBE
RECENT ENDOSCOPY OF BILE DRAINING TUBES
DYSENTRY
WEAK IMMUNE RESPONSE
PERFORATED BOWEL
TRAUMA THAT DAMAGE LIVER
•RISK FACTOR
• INFECTION IN THE BLOOD .
• INFECTION IN BILE DRAINING TUBE .
• RECENT ENDOSCOPY OF BILE TUBE
• ALOHOLISM AND POOR NUTRITION .
• AGE OLDER THAN 70 YEARS .
• MEDICATION LIKE NSAIDS OR CHEMOTHERAPY
• MEDICAL CONDITION SUCH AS CANCER , DIABETES , OR WEAK
IMMUNE SYSTEM .
CLINICAL
MANIFESTATION
• CO U G H
• F E V E R W I T H C H I L L S
• D I A PH O RES I S
• D YS P NEA
• A N O R EX IA
• N AU S E A A N D VO M I T ING
• H E PATOM EG ALY
• JAU N D IC E A N D P R U R I T I S
• S P L E E NOM EGALY
• DA R K U R I N E
• CHALK COLOURED STOOL
• WEIGHT LOSS
• CHEST PAIN
• MAL ARIA
• DULL ABDOMINAL PAIN AND
TENDERNESS IN THE UPPER
RIGHT QUADRANT OF THE
ABDOMEN
DIAGNOSTIC
EVALUATION
ABDOMINAL CT SCAN
ABDOMINAL X-RAY (MAY DEMONSTRATE GAS WITHIN THE
ABSCESS CAVITY 10-20% )
LIVER FUNCTION TEST
BILIRUBIN BLOOD TEST
BLOOD CULTURE COUNT (CBC)
LIVER BIOPSY
LIVER ABSCESS ASPIRATION TO CHECK FOR BACTERIAL
INFECTION IN LIVER ABSCESS
ABDOMINAL ULTRASOUND
TREATMENT
MEDICAL MANAGEMENT
• INTRAVENOUS ANTIBIOTIC THERAPY • DAILY MONITORING OF WEIGHT AND
SKIN TURGOR
• FOOD GIVEN IN SMALL
AND FREQUENT TIME
• PROVIDE COMFORT USING
COMFORT DEVICES
• OPEN SURGICAL
DRAINAGE REQUIRE
ANTIBIOTIC THERAPY
• A CATHETER MAY BE LEFT
IN PLACE FOR
CONTINUOUS DRAINAGE
PHARMACOLOGICAL
MANAGEMENT
• Metronidazole is the drug of choice.
• Earlier the use of emetine and chloroquine was used .
• Metronidazole is effective against both the intestinal
and hepatic phase.
• 750 mg three times a day
for 7–10 days is recommended.
NURSING MANAGEMENT
NURSING
MANAGEMENT• SKIN CARE TO PATIENT WITH DRAINAGE OF ABSCESS .
• VITAL SIGNS MONITORING .
• IV ADMINISTRATION OF ANTIBIOTIC THERAPY .
• REGULAR CBC CHECKING .
• COLD COMPRESS FOR FEVER .
• ANALGESICS
• PROTECTION FROM INFECTION
• REDUCE ANXIETY AND STRESS
• ANTACID
• DIVERTIONAL THERAPY AND NUTRITION MANAGEMENT
DIAGNOSIS• IMPAIRED BREATHING PATTERN RELATED TO DYSPNEA AND
COUGH AS EVIDENSED BY PRESENCE OF HEAVES AND LIFTS
IN PATIENT .
• ACUTE PAIN RELATED TO DISORDER OF SKIN AND MUSCLES
INTEGRITY AS EVIDENCED BY PAIN SCALE .
• FLUID VOLUME DEFICIT RELATED TO RESTRICTED FLUID
INTAKE AS EVIDENCED BY PATIENT VERBALIZTION
• RISK FOR INFECTION TO OPERATED WOUND AND BY
INVASIVE PROCEDURE AS EVIDENCED BY OPEN CUTS AND
INJURIES
HEALTH
EDUCATION
SUMMARY

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Liver abcess made easy

  • 1. LIVER ABCESS PREPARED BY – NUPUR VASHISHT SUBMMITED TO-MRS. NIDHI JOSEPH
  • 4. PHYSIOLOGY• STORAGE OF GLYCOGEN , AMINO ACID AND VITAMIN B12 • SYNTHESIS OF GLUCOSE BY GLUCONEOGENESIS • SECRETION OF BILE • EXCRETION OF CHOLESTROL AND BILE PIGMENTS • DEFENCE OF BODY BY KUPFFER CELLS • HEMATOPOEISIS IN FETUS • DESTRUCTION OF OLD RBC • METABOLISM OF PROTEIN , FATS AND CARBOHYDRATE
  • 6. INTRODUCTION A LOCALIZED INFECTION IN THE LIVER PARECNCHYMA THAT MAY BE BACTERIAL , FUNGAL , PARASITIC IN ORIGIN . APPENDICITIS WITH RUPTURE AND SUBSEQUENT SPREAD OF INFECTION WAS THE MOST COMMON CAUSE OF LIVER ABCESS .
  • 7. DEFINITION •LIVER ABSCESS ARE PURULENT COLLECTION IN THE LIVER PARENCHYMA THAT RESULT FROM BACTERIAL . FUNGAL , OR PARASITIC INFECTION IN WHICH A MASS FILLED WITH PUS IS PRESENT INSIDE THE LIVER .
  • 9. PYOGENIC ABSCESS WHICH IS MOST OFTEN POLYMICROBIAL AND MOSTLY ACCOUNT FOR 80% OF HEPATIC ABSCESS IN US . INTESTINAL MICROBES SUCH AS E.COLLI , STREPTOCOCCUS , AND STAPHYLOCOCCUS .
  • 10. AMOEBIC ABSCESS DUE TO ENTAMOBA HISTOLYTICA ACCOUNT FOR 10 % OF CASES .ITS MOSTLY OCCURING IN THE DEVELOPING COUNTRIES OF TROPICS BECAUSE OF POOR SANITATION AND HYGIENE .
  • 11. FUNGAL ABSCESS MOST OFTEN DUE TO CANDIDA SPECIES , ACCOUNT FOR LESS THAN 10 % OF CASES. MOSQUITO AND NEUTROPENIA FACILITATES THE SPREAD OF ABSCESS FROM GI TRACT TO THE LIVER .
  • 13. PATHOPHYSIOLOGY• INFECTION DEVELOP ANYWHERE ALONG THE BILIARY TRACT OR GI TRACT • INFECTING ORGANISM REACH LIVER THROUGH BILIARY CIRCULATION , HEPATIC ARTERIES • BACTERIA DESTROY NEIGHBOURING LIVER CELLS AND RESULT IN NECROSIS AND SERVE AS A PROTECTIVE WALL FOR THE ORGANISM • MEANWHILE LEUKOCYTES MIGRATE INTO THE INFECTED AREA
  • 14. CONTINUE…..• RESULTS IN LIVER ABSCESS ,CAVITY FULL OF A LIQUID CONTAINING LIVING AND DEAD LEAUKOCYTES , LIQUIFIED LIVER CELLS AND BACTERIA
  • 16. BACTERIAL CAUSES A. STREPTOCOCCUS B. ESCHERICHIA SPECIES C. STAPHYLOCCUS D. KLEBSIELLA E. ENTAMOEBA HISTOLYTICA F. CANDIDA SPECIES
  • 17. POSSIBLE CAUSES ABDOMINAL INFECTION SUCH AS APPENDICITIS , DIVERTICULITIS INFECTION OF BILE DRAINING TUBE RECENT ENDOSCOPY OF BILE DRAINING TUBES DYSENTRY WEAK IMMUNE RESPONSE PERFORATED BOWEL TRAUMA THAT DAMAGE LIVER
  • 18. •RISK FACTOR • INFECTION IN THE BLOOD . • INFECTION IN BILE DRAINING TUBE . • RECENT ENDOSCOPY OF BILE TUBE • ALOHOLISM AND POOR NUTRITION . • AGE OLDER THAN 70 YEARS . • MEDICATION LIKE NSAIDS OR CHEMOTHERAPY • MEDICAL CONDITION SUCH AS CANCER , DIABETES , OR WEAK IMMUNE SYSTEM .
  • 19. CLINICAL MANIFESTATION • CO U G H • F E V E R W I T H C H I L L S • D I A PH O RES I S • D YS P NEA • A N O R EX IA • N AU S E A A N D VO M I T ING • H E PATOM EG ALY • JAU N D IC E A N D P R U R I T I S • S P L E E NOM EGALY • DA R K U R I N E
  • 20. • CHALK COLOURED STOOL • WEIGHT LOSS • CHEST PAIN • MAL ARIA • DULL ABDOMINAL PAIN AND TENDERNESS IN THE UPPER RIGHT QUADRANT OF THE ABDOMEN
  • 22. ABDOMINAL CT SCAN ABDOMINAL X-RAY (MAY DEMONSTRATE GAS WITHIN THE ABSCESS CAVITY 10-20% ) LIVER FUNCTION TEST BILIRUBIN BLOOD TEST BLOOD CULTURE COUNT (CBC) LIVER BIOPSY LIVER ABSCESS ASPIRATION TO CHECK FOR BACTERIAL INFECTION IN LIVER ABSCESS ABDOMINAL ULTRASOUND
  • 24. MEDICAL MANAGEMENT • INTRAVENOUS ANTIBIOTIC THERAPY • DAILY MONITORING OF WEIGHT AND SKIN TURGOR
  • 25. • FOOD GIVEN IN SMALL AND FREQUENT TIME • PROVIDE COMFORT USING COMFORT DEVICES • OPEN SURGICAL DRAINAGE REQUIRE ANTIBIOTIC THERAPY • A CATHETER MAY BE LEFT IN PLACE FOR CONTINUOUS DRAINAGE
  • 26. PHARMACOLOGICAL MANAGEMENT • Metronidazole is the drug of choice. • Earlier the use of emetine and chloroquine was used . • Metronidazole is effective against both the intestinal and hepatic phase. • 750 mg three times a day for 7–10 days is recommended.
  • 28. NURSING MANAGEMENT• SKIN CARE TO PATIENT WITH DRAINAGE OF ABSCESS . • VITAL SIGNS MONITORING . • IV ADMINISTRATION OF ANTIBIOTIC THERAPY . • REGULAR CBC CHECKING . • COLD COMPRESS FOR FEVER . • ANALGESICS • PROTECTION FROM INFECTION • REDUCE ANXIETY AND STRESS • ANTACID • DIVERTIONAL THERAPY AND NUTRITION MANAGEMENT
  • 29. DIAGNOSIS• IMPAIRED BREATHING PATTERN RELATED TO DYSPNEA AND COUGH AS EVIDENSED BY PRESENCE OF HEAVES AND LIFTS IN PATIENT . • ACUTE PAIN RELATED TO DISORDER OF SKIN AND MUSCLES INTEGRITY AS EVIDENCED BY PAIN SCALE . • FLUID VOLUME DEFICIT RELATED TO RESTRICTED FLUID INTAKE AS EVIDENCED BY PATIENT VERBALIZTION • RISK FOR INFECTION TO OPERATED WOUND AND BY INVASIVE PROCEDURE AS EVIDENCED BY OPEN CUTS AND INJURIES