This document provides an overview of cell modification. It defines cell modification as specialized structures or modifications acquired by cells after division to benefit the cell. There are three main types of cell modification: apical, basal, and lateral. Apical modifications include cilia, flagella, microvilli, pseudopods, and extracellular matrix. Basal modifications include hemidesmosomes. Lateral modifications include tight junctions, adhering junctions, and gap junctions. Examples and functions of each type of modification are provided.