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Introduction to  GENERAL PHYSIOLOGY and CELL PHYSIOLOGY Lecture No. 1
General Physiology ,[object Object],[object Object],[object Object]
What is General Physiology? ,[object Object],[object Object],[object Object]
Let’s start with Homeostasis! ,[object Object],[object Object],[object Object]
How does homoestasis take place?
 
 
Blood Calcium levels ,[object Object],[object Object],[object Object],[object Object]
 
Temperature Control ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
Homeostasis & Feedback Control ,[object Object],[object Object],[object Object],[object Object]
Negative Feedback ,[object Object],[object Object],[object Object],[object Object]
What is the Donnan Equilibrium? ,[object Object],[object Object]
What are some of the apparatus  used in Physiology?  Kymograph
POLYGRAPH
MRI & SPIROMETER
MRI & Spirometer ,[object Object],[object Object],[object Object],[object Object]
CT SCAN
COULTER COUNTER
Coulter Counter, Oscilloscope & Ergograph ,[object Object],[object Object],[object Object]
OSCILLOSCOPE & ERGOGRAPH
Blood Pressure Machine
HEMOCYTOMETER
HEMODIALYSIS MACHINE ,[object Object],[object Object]
pH METER & URINOMETER
STETHOSCOPE & PULSE WATCH
AUDIOMETER & TUNING FORK
Audiometer, Tuning Fork & Rubber mallet ,[object Object],[object Object],[object Object]
CELL PHYSIOLOGY
The Cell ,[object Object],[object Object],[object Object],[object Object]
Functions of organelles ,[object Object]
Golgi complex ,[object Object],[object Object],[object Object]
Secretory Pathway in a Cell ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Endoplasmic reticulum ,[object Object],[object Object]
Lysosomes ,[object Object],[object Object]
Microfilaments This is a flourescence digital image of a fibroblast showing actin cytoskeletal network .
Microfilaments ,[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object]
The Nucleus ,[object Object],[object Object],[object Object],[object Object],[object Object],Heterochromatin  – forms the condensed or coiled parts of the chromosomes (metabolically inert) Euchromatin  – forms the dispersed or extended parts of the chromosomes (metabolically active)
The Genetic Code   ,[object Object],[object Object],[object Object],[object Object]
Nucleotides ,[object Object],[object Object]
Types of RNA
Types of RNA in a Gene
Ribosomal RNA (rRNA) ,[object Object],[object Object]
Types of RNA ,[object Object],[object Object],[object Object],[object Object]
Translation and Transcription ,[object Object],[object Object]
History of the Plasma Membrane ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Plasma Membrane is made of Phospholipids ,[object Object],[object Object],[object Object],[object Object],[object Object]
Plasma Membrane Models ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Which membrane model is correct? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Fluid-Mosaic Model ,[object Object],[object Object],[object Object],[object Object]
Structure of the Plasma Membrane
Structure of the Plasma Membrane ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Proteins of the Plasma Membrane Provide 6 Membrane Functions: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
1)   Transport Proteins ,[object Object],[object Object]
2)   Receptor Proteins ,[object Object]
3)   Enzymatic Proteins ,[object Object]
4)   Cell Recognition Proteins ,[object Object]
5)   Attachment Proteins ,[object Object],[object Object],[object Object]
6)   Intercellular Junction Proteins ,[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],How do materials move into and out of the cell?
Plasma Membrane Transport ,[object Object],Passive Transport Active Transport
What are three types of  passive transport? ,[object Object],[object Object],[object Object],Passive Transport ATP energy is  not  needed to move the molecules through.
Passive Transport 1: Diffusion ,[object Object],[object Object],DIFFUSION
What is Diffusion? ,[object Object],[object Object],http://www.biologycorner.com/resources/diffusion-animated.gif
What molecules pass through the plasma membrane by diffusion ? ,[object Object],[object Object],[object Object],[object Object],[object Object]
Why is diffusion important to cells and humans? ,[object Object],[object Object],[object Object],[object Object],[object Object]
Passive Transport 2 : Facilitated Diffusion ,[object Object],[object Object],FACILITATED DIFFUSION
What is Facilitated Diffusion? ,[object Object]
What molecules move through the plasma membrane by facilitated diffusion? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
How do molecules move through the plasma membrane by facilitated diffusion? ,[object Object],[object Object],[object Object],[object Object]
Specific Types of Facilitated Diffusion ,[object Object],[object Object],[object Object]
Why is facilitated diffusion important to cells and humans? ,[object Object],[object Object],[object Object],[object Object]
Passive Transport 3: Osmosis ,[object Object],[object Object],OSMOSIS
What is Osmosis ? ,[object Object]
Osmosis in action ,[object Object],[object Object]
 
Why is osmosis important to cells and humans? ,[object Object],[object Object],[object Object]
Osmosis and Tonicity ,[object Object],[object Object],[object Object],[object Object],[object Object]
Isotonic ,[object Object],[object Object],[object Object],[object Object]
Hypotonic ,[object Object],[object Object],[object Object],[object Object],[object Object]
Hypertonic ,[object Object],[object Object],[object Object],[object Object]
 
Review: Passive Transport ,[object Object],[object Object],[object Object]
Review Tonicity ,[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],What are three types of  Active transport? Active Transport ATP energy is  required  to move the molecules through.
Active Transport ,[object Object],[object Object]
The Importance of Active Transport ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
The Sodium-Potassium Pump ,[object Object],[object Object],[object Object],http://www.biologie.uni-hamburg.de/b-online/library/biology107/bi107vc/fa99/terry/images/ATPpumA.gif
The Role of the Na +- K +  Pump ,[object Object],[object Object],[object Object],[object Object],[object Object]
Active Transport 2 :  Exocytosis ,[object Object],[object Object]
Active Transport 3 :  Endocytosis ,[object Object],[object Object],[object Object],[object Object],[object Object]
Phagocytosis ,[object Object],[object Object],[object Object]
Pinocytosis ,[object Object],[object Object]
Receptor-Mediated Endocytosis ,[object Object],[object Object],[object Object]
Types of Endocytosis ,[object Object],[object Object],[object Object]
SURFACE TENSION   IS THE TENDENCY FOR A LIQUID TO CONTRACT AS A CONSEQUENCE OF ITS POSSESION OF FREE ENERGY, SINCE APPROACH TO EQUILIBRIUM IS ALWAYS ACCOMPANIED BY A DIMINUTION OF FREE ENERGY .   We’ve all played with it- water drops being added one at a time, until that one drop breaks the surface and the water spills out.
IT IS HARD TO BELIEVE THAT H-BONDS AND SURFACE TENSION ARE ENOUGH TO KEEP THE VOLUME OF WATER THAT IS IN THESE BEADS STUCK TO THE PLANT
What are biologic activities which can be best explained in terms of surface tension? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
DIALYSIS is the separation of the more diffusible from the less diffusible
Types of Cell Junctions ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Tight Junctions ,[object Object],[object Object],[object Object]
Desmosomes ,[object Object],[object Object],[object Object]
Gap Junctions ,[object Object],[object Object],[object Object]
 
Plasmodesmata ,[object Object],[object Object],[object Object]
Types of Cell Junctions ,[object Object]
 
DIFFUSION
What are the factors which influence diffusion? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
DIFFUSION
 
DIFFUSION
ACTION POTENTIAL
Events During an Action Potential ,[object Object],[object Object],[object Object],[object Object]
 
 
Next Meeting ,[object Object],[object Object],[object Object],[object Object]

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