This document describes the process of ingestion, digestion and absorption of food by the gastrointestinal system. It discusses the roles of the mouth, esophagus, stomach, small intestine and colon. The mouth chews and swallows food which is propelled through the esophagus to the stomach. The stomach stores, mixes and slowly empties food chunks (chyme) to the small intestine where nutrients are absorbed. The colon absorbs water from waste and stores feces until defecation. Regulatory mechanisms such as hormones and nerves coordinate movement and emptying between organs.
Gastrointestinal Hormones by Pandian M, Dept of Physiology DYPMCKOP, for MBBS...Pandian M
Classify GIT hormones
List the source and functions of different GI hormones
Explain the mechanism of action and regulation of secretion of different GI Hormones
Describe the role of GI hormones in regulation of GI functions
Explain the dysfunctions produced by alteration in secretion of GIT hormones
FUNCTIONAL ANATOMY
INTESTINAL VILLI AND GLANDS
PROPERTIES AND COMPOSITION OF SUCCUS ENTERICUS
FUNCTIONS OF SUCCUS ENTERICUS
FUNCTIONS OF SMALL INTESTINE
REGULATION OF SECRETION OF SUCCUS ENTERICUS
METHODS OF COLLECTION OF SUCCUS ENTERICUS
APPLIED PHYSIOLOGY
Gastrointestinal Hormones by Pandian M, Dept of Physiology DYPMCKOP, for MBBS...Pandian M
Classify GIT hormones
List the source and functions of different GI hormones
Explain the mechanism of action and regulation of secretion of different GI Hormones
Describe the role of GI hormones in regulation of GI functions
Explain the dysfunctions produced by alteration in secretion of GIT hormones
FUNCTIONAL ANATOMY
INTESTINAL VILLI AND GLANDS
PROPERTIES AND COMPOSITION OF SUCCUS ENTERICUS
FUNCTIONS OF SUCCUS ENTERICUS
FUNCTIONS OF SMALL INTESTINE
REGULATION OF SECRETION OF SUCCUS ENTERICUS
METHODS OF COLLECTION OF SUCCUS ENTERICUS
APPLIED PHYSIOLOGY
Intestines(movements and secretions of small and large intestines ) The Guyto...Maryam Fida
Intestines(movements and secretions of small and large intestines)
Distended Portion of small intestine with chyme stretching concentric contractions at intervals lasting a fraction of a minute These contraction causes “Segmentation” of the small intestine ---forms spaced segments new points every time chopping chyme 2-3 times/min mixing with intestinal secretions maximum frequencyof segmentation contraction depends on frequency of BER (Basic electrical rhythm) i.e. In duodenum and proximal jejunum is 12/min and in terminal ileum is 8-9/min.
Atropine blocks the segmentation
law of gut
The peristaltic reflex +anal direction of movement of the peristalsis is called “LAW OF GUT”
Movements in the GIT( the guyton and hall physiology)Maryam Fida
movements in GIT
1. Propulsive Movements -------- Peristalsis
2. Mixing Movements
Moves food forward along GIT at an appropriate rate for digestion and absorption
A contractile ring appears around the gut and then moves forward
Stimulation at any point in the gut can cause a contractile ring to appear in the circular muscle, and this ring then spreads along the gut tube
Directional movement toward Anus
Can occur in either direction but normally occurs towards anus
Requires active myenteric plexus
Stimulus for intestinal peristalsis
Distention of the gut
Irritation
Parasympathetic nervous signals
Peristalsis is absent:
Congenital absence of myenteric plexus
Atropine (paralyzes cholinergic nerve endings)
Peristalsis also occurs in
Bile ducts
Glandular ducts
Ureters
Many other smooth muscle tubes of the body
Law of the Gut or Peristaltic Reflex or Myenteric reflex:
Peristaltic reflex plus anal direction of movement of peristalsis is called "law of the gut”
Contractile ring normally begins on orad side of distended segment
The gut sometimes relaxes several centimeters downstream toward the anus, called "receptive relaxation," thus allowing food to be propelled easily anally
Common medication used for anesthesia, there action; dosage; adverse effect; duration of action.
They Include {inhalation + Induction + Muscle relaxant + Anticholinergic + Analgesic + Resuscitation}
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When the pituitary Gland it' s function is increased whether the cause are?
Both anterior and Posterior gland secretions are increased the most causes are ADENOMAS
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This note paper is short notes of general physiology for medical students who which to understand the concept of the physiology, physiology is the mother of medicine.
A summary of skeletal muscle contraction and relaxationAyub Abdi
it consist for 4 pages and cover all the steps that occur during muscle contraction and relaxation, I does not take a time just 5 minute is enough to read. I hope it's interesting.
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Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
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micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
2. INGESTION OF FOOD:
• Hunger: is an intrinsic desire that the
person needs to ingest enough food.
• Appetite: Is the type of food that a
person preferentially seeks.
3. MASTICATION (CHEWING):
• The teeth is responsible for chewing.
• The anterior teeth (incisors) provide a strong
cutting action, and the posterior teeth
(molars) provide a grinding action.
• Chewing reflex is done by rebound
contraction.
• Most of the muscles of chewing are
innervated by the motor branch of the fifth
cranial nerve.
4.
5. SWALLOWING
(DEGLUTITION):
• Is a complicated mechanism, principally
because the pharynx subseries respiration and
swallowing.
• Swallowing can be divided into:
(1) A Voluntary Stage.
(2) A Pharyngeal Stage.
(3) An Esophageal Stage.
6.
7. • The esophagus functions primarily to conduct food rapidly
from the pharynx to the stomach.
• The esophagus normally exhibits two types of peristaltic
movements:
1- Primary peristalsis
2- Secondary peristalsis
1- Primary peristalsis:
• Is simply continuation of the peristaltic wave that begins
in the pharynx and spreads into the esophagus during the
pharyngeal stage of swallowing.
• 8 to 10 seconds, 5 to 8 seconds (gravity pulling).
• If the primary peristaltic wave fails to move all the food
then secondary peristaltic waves initiates.
8. 2- Secondary peristalsis:
• Result from distention of the esophagus itself by the
retained food.
• Initiated partly by:
A. intrinsic neural circuits in the myenteric nervous
system.
B. Glossopharyngeal and vagal efferent nerve fibers.
• Function of the Lower Esophageal Sphincter
(Gastroesophageal Sphincter) = prevent significant
reflux of stomach contents into the esophagus.
• Additional Prevention of Esophageal Reflux by
Valvelike Closure of the Distal End of the
Esophagus.
11. MOTOR FUNCTIONS OF THE
STOMACH:
(1) storage of large quantities of food until the food
can be processed in the stomach, duodenum, and
lower intestinal tract.
(2) mixing of this food with gastric secretions until it
forms a semifluid mixture called chyme.
(3) slow emptying of the chyme from the stomach
into the small intestine at a rate suitable for
proper digestion and absorption by the small
intestine.
15. MIXING AND PROPULSION OF FOOD
IN THE STOMACH:
• Gastric glands of the stomach secretes the digestive juices.
• The long presence of food causes mixing waves which is a
weak peristaltic constrictor waves.
• every 15 to 20 seconds.
• Powerful peristaltic action potential–driven constrictor
rings that force the antral contents under higher and
higher pressure toward the pylorus.
• “Retropulsion”: is the combination of pyloric squeezing
and constrictive peristalsis in the stomach.
• Hunger Contractions: when the stomach has been empty
for several hours or more. And the whole stomach
contracts.
• Hunger pangs: mild pain in the pit of stomach.
16.
17. STOMACH EMPTYING:
• “Pyloric pump”: Is promoted by intense peristaltic
contractions in the stomach antrum.
Control of Stomach Emptying:
1- Stomach factors:
• Degree of filling.
• Effect of gastrin.
2- Duodenal factors (inhibitory feedback):
• Enterogastric inhibitory nervous feedback
reflexes.
• Hormonal feedback by Cholecystokinin (CCK).
18. • Hormone gastrin from the G cells of the antral mucosa.
• Cause secretion of highly acidic gastric juice by the stomach glands.
• Gastrin likely promotes stomach emptying.
• Increased food volume in the stomach promotes increased
emptying from the stomach.
• Stretching of the stomach wall does elicit local myenteric reflexes in
the wall
• Multiple nervous reflexes are initiated from the duodenal wall
(enteric nervous system, inhibitory sympathetic nerve fibers in
stomach, inhibation vagus nerves in stomach).
• Hormones cholecystokinin from mucosa of the jejunum.
• Inhibitor to block increased stomach motility caused by gastrin.
• Secretin and glucose-dependent insulinotropic peptide, also called
gastric inhibitory peptide (GIP).
20. MIXING CONTRACTIONS
(SEGMENTATION CONTRACTIONS):
• The contraction of the intestine they divide
the intestine into spaced segments that have
the appearance of a chain of sausages.
• Chyme is propelled through the small intestine
by peristaltic waves.
• Peristaltic activity of the small intestine is
greatly increased after a meal.
• chyme into the duodenum, causing stretch of
the duodenal wall.
21.
22. • Factors that enhance the intestinal motility are:
1. gastrin,
2. CCK,
3. insulin,
4. motilin, and
5. serotonin.
• Factors that inhibit the intestinal motility are:
1. secretin
2. glucagon
23. • Function of the peristaltic intestinal wave is:
1. Spread of chyme to the intestinal mucosa.
2. Progression of chyme toward the ileocecal valve.
• When reaching the chyme in the ileocecal valve they
blocked for several hours until the person eat
another meal then the gastroileal reflex begins
which intensifies the peristalsis in the ileum and
forces the remaining chyme through the ileocecal
valve into the cecum of the large intestine.
24. • Peristalsis in the small intestine is normally weak.
• Peristaltic rush is a “powerful and rapid peristalsis”
caused by intense irritation to the intestinal mucosa as a
result of infectious diarrhae.
• The ileocecal valve prevents backflow from the colon to
the small intestine.
• Ileocecal sphincter is a thickened circular muscle.
• Feedback control of the ileocecal sphincter:
• When the cecum is distended, contraction of the ileocecal
sphincter becomes intensified and ileal peristalsis is
inhibited – delay emptying. Ex:
1. Inflamed appendix.
2. Partial paralysis of the ileum.
26. • The principal functions of the colon are:
(1) absorption of water and electrolytes from
the chyme to form solid feces.
(2) storage of fecal matter until it can be
expelled.
The proximal half of the colon – absorption.
The distal half of the colon – storage.
Movement of colon is by two process:
Mixing Movements—“Haustrations.”
Propulsive Movements—“Mass Movements.”
27. Mixing Movements—“Haustrations”:
• Same manner that segmentation movements occur in the
small intestine.
• This process done by means of contraction of circular
muscles of large intestine, but in some cases leads to
intestinal occlution.
• The circular and lungitudinal muscels “which is formed by
3 strips called tenea coli” contractes leading to bulge feces
outward into baglike sacs called haustrations.
• Each haustration reaches peak intensity in about 30
seconds and then disappears during the next 60 seconds.
• in the cecum and ascending colon they slowly propulse the
colonic content.
• 80 to 200 milliliters of feces are expelled each day.
28.
29. Propulsive Movements—“Mass
Movements”:
• From the cecum to the sigmoid, mass movements can take over
the propulsive role.
• one to three times each day.
• A mass movement is a modified type of peristalsis
characterized:
1. a constrictive ring occurs in response to a distended or irritated
point in the colon, usually in the transverse colon.
2. propelling the fecal material in this segment en masse further
down the colon.
• A series of mass movements usually persists for 10 to 30
minutes.
• They then cease but return perhaps a half day later.
• When they have forced a mass of feces into the rectum, the
desire for defecation is felt.
30.
31. Initiation of Mass Movements by
Gastrocolic and Duodenocolic Reflexes:
• These reflexes result from distention of the
stomach and duodenum.
• Irritation in the colon can also initiate intense
mass movements.
• A person with (ulcerative colitis) frequently
has mass movements that persist almost all
the time.
32. DEFECATION or EGECTION:
• The rectum is empty of feces because a weak
functional sphincter exists.
• A sharp angulation contributes additional resistance
to filling of the rectum.
• When a mass movement forces feces into the rectum,
the desire for defecation occurs immediately,
including reflex contraction of the rectum and
relaxation of the anal sphincters.
• Continual dribble of fecal matter through the anus is
prevented by tonic constriction of:
(1) an internal anal sphincter
(2) an external anal sphincter
33. • The external sphincter is
controlled by nerve fibers
in the pudendal nerve,
which is part of the
somatic nervous system
and therefore is under
voluntary, conscious, or at
least subconscious
control.
• subconsciously, the
external sphincter is
usually kept continuously
constricted unless
conscious signals inhibit
the constriction.
34. Defecation Reflexes:
• Is done by Intrinsic reflex mediated by the local enteric
nervous system in the rectal wall.
1. First feces enter the rectum.
2. Distention of the rectal wall initiates afferent signals
that spread through the myenteric plexus to initiate
peristaltic waves in the descending colon, sigmoid, and
rectum, forcing feces toward the anus.
3. The internal anal sphincter is relaxed by inhibitory
signals from the myenteric plexus.
4. If the external anal sphincter is also consciously,
voluntarily relaxed at the same time, defecation occurs.
• Parasympathetic fortified defecation reflex.
35.
36.
37.
38. • Defecation signals entering the spinal cord initiate
other effects, such as taking a deep breath, closure
of the glottis, and contraction of the abdominal
wall muscles.
The peritoneointestinal reflex results from irritation of
the peritoneum; it strongly inhibits the excitatory enteric
nerves and thereby can cause intestinal paralysis, especially
in patients with peritonitis.
The renointestinal and vesicointestinal reflexes inhibit intestinal
activity as a result of kidney or bladder irritation.