Layer of Protection Analysis (LOPA) is an effective semi-quantitative tool for process hazard analysis and risk assessment. It lies between qualitative and quantitative analysis. LOPA evaluates risks by analyzing accident scenarios, their likelihood and severity. It also considers independent protective layers that can prevent or mitigate consequences. The key steps of LOPA include establishing consequence criteria, identifying scenarios, evaluating frequency and severity, examining protective layers, and comparing results to risk tolerance limits. LOPA is useful for decision making regarding safety systems and managing risks cost effectively.