The document compares Layer of Protection Analysis (LOPA) and Hazard and Operability Study (HAZOP), highlighting LOPA as a semi-quantitative method for estimating risk reduction through independent safety layers. It details the layers of protection in a facility, each with specific probabilities of failure and illustrates the application of LOPA in a batch reactor scenario. Additionally, it defines Safety Integrity Levels (SILs), which measure the reliability of safety systems based on their probability of failure on demand.