We all know how COVID is affecting all our lives, we see people getting themselves tested for the infection, we merely know what is the procedure and what are the tests done. We all know the noble Coronavirus replicates some of its functioning and symptoms to that of the SARS virus. However, the SARS-CoV-2 virus has an e-gene which makes it envelope around the viral shell making the enzyme RNA dependent RNA Polymerase. It takes almost 24-48 hrs to get the results if the test confirms the person is COVID positive or negative.

1. Lab test for COVID-19 explained!

2. We all know how COVID is affecting all our lives, we see people getting themselves tested
for the infection, we merely know what is the procedure and what are the tests done.
We all know the noble Coronavirus replicates some of its functioning and symptoms to that
of the SARS virus. However, the SARS-CoV-2 virus has an e-gene which makes it envelope
around the viral shell making the enzyme RNA dependent RNA Polymerase. It takes almost
24-48 hrs to get the results if the test confirms the person is COVID positive or negative. So
when the test is processed most emphasis is put up on the E-gene. The following reaction
results in severe acute respiratory issues syndrome. It mainly attacks the respiratory and
gastrointestinal tract infections. It is said that the respiratory illness is due to the virus of
Betacoronavirus genus.

3. Initially, when the very first few cases were reported in Hubei, China about the increasing
cases of pneumonia, the doctors referred it to the old 2003 SARS virus outbreak which
resulted in severe acute respiratory disease. As the cases increased and doctors and scientists
performed the tests vigorously they found out the etiologic and epidemiologic results. The
results showed that only 1% of patients had direct contact with the animal-wholesale market
whereas others were affected locally. It is then when the coronavirus transmission was
predicted.
The virus was detected in the reverse transcription-polymerase chain reaction which is, it
converts RNA to DNA. The RT-PCR can detect only the SARS-CoV-2 which contains only
RNA.

4. There are a lot of combinations of techniques known as Real-time RT-PCR. The further tests
are done by throat swab, nasopharyngeal swab, deep-airway material using suction, or
through saliva. Sputum i.e the cough materials play a major role in detecting if the person is
infected or not. Because through throat swab it can only be detected if the test is done by the
first week itself or else the virus might run down to lungs and multiply there.

5. Reference:
https://en.wikipedia.org/wiki/COVID-19_testing
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7180649/
https://www.the-scientist.com/news-opinion/how-sars-cov-2-tests-work-and-whats-next-in-
covid-19-diagnostics-67210
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