Kim Solez 204 years of Banff spirit new January 7 2019Kim Solez ,
Kim Solez 204 years of Banff spirit new January 7 2019 Slide show for 60 inch wall screen in cyberNephrology 145 slides new David Crippen Cuba slide is number 36
Kim Solez 384 years of banff spirit new june 26 2019Kim Solez ,
Kim Solez 384 years of Banff spirit new June 26 2019 The most remarkable slide is number 137. "By Spring of 2019 every erroneous statement we complained about had been reversed. We celebrated by creating a new video trailer on our YouTube channel on June 25 2019." How about that!
Kim Solez 204 years of banff spirit November 10 2017Kim Solez ,
Kim Solez 204 years of banff spirit and local heroes, presentation for wall mounted screen in cyberNephrology office, November 10, 2017. Copyright (c) 2017, JustMachines Inc.
Kim Solez 204 years of Banff spirit new January 7 2019Kim Solez ,
Kim Solez 204 years of Banff spirit new January 7 2019 Slide show for 60 inch wall screen in cyberNephrology 145 slides new David Crippen Cuba slide is number 36
Kim Solez 384 years of banff spirit new june 26 2019Kim Solez ,
Kim Solez 384 years of Banff spirit new June 26 2019 The most remarkable slide is number 137. "By Spring of 2019 every erroneous statement we complained about had been reversed. We celebrated by creating a new video trailer on our YouTube channel on June 25 2019." How about that!
Kim Solez 204 years of banff spirit November 10 2017Kim Solez ,
Kim Solez 204 years of banff spirit and local heroes, presentation for wall mounted screen in cyberNephrology office, November 10, 2017. Copyright (c) 2017, JustMachines Inc.
Bullying Essay | Essay on Bullying Essay for Students and Children in .... Buy Cause And Effect Essay On Bullying Spm, bullying cause effect and .... Bullying In Schools Essay - bullying. Essay on bullying prevention. Argumentative Essay About Bullying : 015 Bullying Essay Report School .... Help me do my essay we must stop verbal bullying - websitereports359 .... School bullies essay spm. Bullying in Schools Essay | Essay on Bullying in Schools for Students .... Bullying Essay: 8-Step Way to High Grades | Pro Essay Help. Complete Research Paper About Bullying. Bullying essay - College Homework Help and Online Tutoring..
Kim Solez Charles dickens and transplant pathologyKim Solez ,
Acceptance speech by Dr. Kim Solez receiving the Catalan Society of Transplantation Gold Medal on behalf of himself and Dr. Lorraine Racusen March 31, 2017
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Problem Solution Essay Prompts. How to Write a Problem Solution Essay: Guide ...Danielle Torres
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Kim Solez Mallory Chipman AHHM pathology meets faatjKim Solez ,
Kim Solez and Mallory Chipman present in the AHHM Speaker Series "Pathology Meets the Future and All That Jazz: AI, Regenerative Medicine and You" at the University of Alberta Arts and Humanities in Health and Medicine program speaker series on December 8, 2016 . Copyright (c) 2016, JustMachines Inc.
Bullying Essay | Essay on Bullying Essay for Students and Children in .... Buy Cause And Effect Essay On Bullying Spm, bullying cause effect and .... Bullying In Schools Essay - bullying. Essay on bullying prevention. Argumentative Essay About Bullying : 015 Bullying Essay Report School .... Help me do my essay we must stop verbal bullying - websitereports359 .... School bullies essay spm. Bullying in Schools Essay | Essay on Bullying in Schools for Students .... Bullying Essay: 8-Step Way to High Grades | Pro Essay Help. Complete Research Paper About Bullying. Bullying essay - College Homework Help and Online Tutoring..
Kim Solez Charles dickens and transplant pathologyKim Solez ,
Acceptance speech by Dr. Kim Solez receiving the Catalan Society of Transplantation Gold Medal on behalf of himself and Dr. Lorraine Racusen March 31, 2017
Essay on Music Music Essay for Students and Children in English - A .... Calaméo - Downloading Music Essay: Ideas to Be Developed in Your Paper. Best Music Essay Thatsnotus. Music essay. 004 Musicessay Jazz Phpapp01 Thumbnail Music Essay Thatsnotus. 014 Essay Example I Believe In Music Sample Narrative College About .... Musicopen handed essay. Music Essay Help Proven Tips Best Ideas Pro Essay Help. My Hobby is Listening to Music Essay Example Essay writing examples .... MUSIC AND US2 - 3AM: 13 - GOOD EXAMPLE OF ESSAY WRITING. ACAccounting - Music Essay - Music Essay Music can be the most .... Music And Its Importance Essay Essay on Music and Its Importance for .... Music Essay by Teodor - Issuu. Best Essay About Music Thatsnotus. 004 Music Essays Narrative Essay Writing Thesis Word College Musical .... Music Essay. Classification of Music: Essay Sample - Free Essay, Term Paper .... Music Essay Introduction. Essay Writing for Music Essays Paragraph. essay about music Essay about life, Essay, Sample essay. Scholarship essay: Essay on music. 020 Essay Example Editorial Music Thatsnotus. Personal essays about music - Free essay about music!. A level music essay writing. Sample Music Essay PDF Rhythm Musical Compositions. 017 Song Essay Example Writing Lyrics How To Format Lyric Sheet .... My kind of music essay. Music Essay for Students in English. 2022-11-07. College Essay: Music for writing essays Music Essays Music Essays
Problem Solution Essay Prompts. How to Write a Problem Solution Essay: Guide ...Danielle Torres
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Essays On Technology. Essay on Technology for Students amp; Children 600 Word...Britney Gilbert
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Kim Solez Mallory Chipman AHHM pathology meets faatjKim Solez ,
Kim Solez and Mallory Chipman present in the AHHM Speaker Series "Pathology Meets the Future and All That Jazz: AI, Regenerative Medicine and You" at the University of Alberta Arts and Humanities in Health and Medicine program speaker series on December 8, 2016 . Copyright (c) 2016, JustMachines Inc.
Similar to Kim Solez 204 years of banff spirit9 new May 10 2019 (17)
Slide deck for annual meeting of Transplant Regenerative medicine Community of Practice of American Society of Transplantation at noon in Room 204 in John B. Hynes Convention Center. Everyone welcome! Many exciting initiatives to discuss!
Kim Solez Xenotransplantation- The Rest of the Story April 8 2022 6.pptxKim Solez ,
Nephrology Grand Rounds Presentation at the University of Alberta discussing the big picture issues surrounding xenotransplantation and its relation to stem cell generated organs and bioengineered organs in the future
Kim Solez Hooking-Up Physical Forces Optimism and Dark Energy Presentation Se...Kim Solez ,
Kim Solez Banff New Media Institute Presentation, "Smart, Sexy, Healthy" ThinkTank, Sept 6 2001
Hooking-Up, Physical Forces, Optimism and Dark Energy: Imagery, Hope, and Health.
Kim Solez Grand rounds Feb 1, 2019 Seizing the opportunity of technology and ...Kim Solez ,
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Kim Solez Ishita Moghe Seizing the opportunity of technology and the future of medicine creating the possibility of a positive medical future for everyone1 Medical Grand Rounds Presentation Feb. 1, 2019.
Basavarajeeyam is an important text for ayurvedic physician belonging to andhra pradehs. It is a popular compendium in various parts of our country as well as in andhra pradesh. The content of the text was presented in sanskrit and telugu language (Bilingual). One of the most famous book in ayurvedic pharmaceutics and therapeutics. This book contains 25 chapters called as prakaranas. Many rasaoushadis were explained, pioneer of dhatu druti, nadi pareeksha, mutra pareeksha etc. Belongs to the period of 15-16 century. New diseases like upadamsha, phiranga rogas are explained.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
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These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
The Gram stain is a fundamental technique in microbiology used to classify bacteria based on their cell wall structure. It provides a quick and simple method to distinguish between Gram-positive and Gram-negative bacteria, which have different susceptibilities to antibiotics
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
CDSCO and Phamacovigilance {Regulatory body in India}NEHA GUPTA
The Central Drugs Standard Control Organization (CDSCO) is India's national regulatory body for pharmaceuticals and medical devices. Operating under the Directorate General of Health Services, Ministry of Health & Family Welfare, Government of India, the CDSCO is responsible for approving new drugs, conducting clinical trials, setting standards for drugs, controlling the quality of imported drugs, and coordinating the activities of State Drug Control Organizations by providing expert advice.
Pharmacovigilance, on the other hand, is the science and activities related to the detection, assessment, understanding, and prevention of adverse effects or any other drug-related problems. The primary aim of pharmacovigilance is to ensure the safety and efficacy of medicines, thereby protecting public health.
In India, pharmacovigilance activities are monitored by the Pharmacovigilance Programme of India (PvPI), which works closely with CDSCO to collect, analyze, and act upon data regarding adverse drug reactions (ADRs). Together, they play a critical role in ensuring that the benefits of drugs outweigh their risks, maintaining high standards of patient safety, and promoting the rational use of medicines.
Adv. biopharm. APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMSAkankshaAshtankar
MIP 201T & MPH 202T
ADVANCED BIOPHARMACEUTICS & PHARMACOKINETICS : UNIT 5
APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMS By - AKANKSHA ASHTANKAR
Adv. biopharm. APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMS
Kim Solez 204 years of banff spirit9 new May 10 2019
1. Kim Solez World Exponential Timeline
From Homer Smith 1895 to Aug. 7, 2099
1934 Leonard
Cohen
1941 Paul Simon 1945 Rod Stewart 1991 Ed Sheeran
1994 Mallory Chipman
1901 Louis
Armstrong
1920 Robert
Heptinstall
1943
Janis
Joplin
1961 Peter
Diamandis
2. Think Different
It is different to mix
science, music, and
poetry together as
we have done in this
presentation!
3. Think Different – Kim Solez sharing
cyberNephrology 5B3.09 WCM HSC with
Students & Fellows
Annette Shaff / Shutterstock.com
4. 204 Years of the Spirit of Banff 1895-2099 122
Back 82 Forward
5. Homer Smith, born 1895, turned Kim on to the
kidney in med school 3rd yr.
6. Homer Smith born 1895 Turned me on to
kidney in med school 3rd year .
9. Solez, Morel-Maroger, and Sraer
Medicine 58:362-376, 1979. Morphology
of "acute tubular necrosis" in man:
Analysis of 57 renal biopsies and
comparison with the glycerol model. My
most cited paper before coming to
Edmonton as Chair of Pathology.
10. Solez, Morel-Maroger, and Sraer
Medicine 58:362-376, 1979
1. Of the 12 lesions assessed in the 57 “ATN”
biopsies 10 persisted after functional
recovery. Only 2 lesions correlated with
function, were present when renal failure
was present and absent after recovery:
1)thinning of PAS positive brush border, & 2)
shedding of individual tubular epithelial cells
leaving bare basement membrane.
11. Solez, Morel-Maroger, and Sraer
Medicine 58:362-376, 1979
2. Lesions which persisted after recovery of
function included tubular dilation, regeneration,
mitoses, casts, interstitial edema, inflammation,
nucleated cells in vasa recta, dilation of
Bowman’s capsule, tubularization of Bowman’s
capsule epithelium, & juxtaglomerular
apparatus hyperplasia. The latter two were
more prominent in recovery biopsies.
12. Solez, Morel-Maroger, and Sraer
Medicine 58:362-376, 1979
3. Lumping all acute tubular injury lesions
together guarantees that histology assessment
will appear to be inferior to molecular
assessment, since the majority of ATI lesions
persist after functional recovery. Only studies
which separately assess the two lesions which
correlate functionally are valid. i.e. 1)thinning or
absence of PAS positive brush border, & 2)
shedding of individual tubular epithelial cells .
13. Paper still referred to in recent reviews,
findings uncontested.
Basile et al., 2012
14. Cannot say molecules change faster than
morphology until you look at these two
lesions, BB loss and cell exfoliation!
Basile et al., 2012
16. Later work on Transplant Acute Tubular Injury
Was an Important Antecedent to Banff Studies
1993 KI paper on Transplant ATI.
17. New insights into transplant ATN, Solez et al. 1993
Brush border loss not a feature of transplant ATN.
18. Forty years later a more nuanced
understanding of the post ischemic kidney
is that tubular injury and microvascular
injury are separable components which
can be influenced in opposite ways by
pharmacologic interventions. Both types
of injury contribute to renal functional
impairment. These issues are the subject
of major precision medicine initiatives
which should bear fruit in 2019-2020.
20. Nine months after meeting Kim Solez over 3 day
weekend in 2005 Leonard wrote song inspired by
their discussion of Banff borderline changes.
21. Ten years later Leonard removed all but one of the
borderlines and the song became the popular
“Treaty” on the 2016 You Want It Darker album.
“I wish there was a treaty we could sign
I do not care who takes this bloody hill …
I wish there was a treaty we could sign
It’s over now the water and the wine
We were broken then but now we’re borderline
I wish there was a treaty
I wish there was a treaty
Between your love and mine”
The notebook pages showing this ten year song transition were the
only such pages reproduced in the program for the “Tower of Song”
Tribute Concert in Montreal at the Bell Centre November 6th, 2017.
22. Paul Simon, born 1941, has inspired Kim with
his lyrics for a long time
46. Kim Solez with meeting coordinator Michele
Hales in 2002 in Pennan.
47. 2003 image from Aberdeen Banff meeting.
Lorraine Racusen is in the center and
Michele Hales is beside her. Phil Halloran is
behind Michele. Jake Demetris is at far left.
48. Tori Sheldon and Akshatha Raghuveer. In 2007 we
lost our funding from the NKF and student staffing
began.
56. In 1991 Kim Solez and Lorraine Racusen Directed the First Banff Meeting
Which Created the Banff Classification of Transplant Pathology and Banff
Consensus Process
Classification established, lesion scoring,
diagnostic categories, physician-led consensus
57. BANFF CLASSIFICATION STANDARD FOR
TRANSPLANT BIOPSY INTERPRETATION
Began in kidney (Solez et al. 1993), and was then extended
to liver, pancreas, composite tissue grafts etc. Meetings
also consider heart, lung, small bowel.
Uses semiquantitative lesion scoring 0-3+ and diagnostic
categories. A pathologic classification of all pathologic
changes, not just rejection.
58. 1993 Meeting was joint with Canadian
Association of Pathologists – Future
Consortium was Important Antecedent
1993 Meeting - Liver classification, chronic rejection, first presentation on
molecular pathology approaches, CAP Future of Pathology Consortium consensus discussions
1988-94 were an important antecedent to Banff consensus discussions .
59. 1995 Banff meeting at Banff Centre for
Conferences Group Picture of Liver Attendees
60. 1995 Shot - Bruce McManus in Center, Pekka Hayry
Behind, Fred Sanfillipo in Doorway - Who Else Can
You Identify?
61. More 1995 Shots
Kim Solez and Lorraine Racusen
1995 Meeting - Pancreas classification, glomerulitis, first international medical meeting on
CD-ROM, first Banff conference with microscope sessions. Lesion scoring normalized with CADI.
62. 1997 Meeting – Banff Springs Hotel
1997 Meeting - Merging of Banff and CCTT classifications, establishing basis for current Banff
classification, post-transplant lymphoproliferative disorder, first Banff conference with posters.
63. 1999 Meeting - Larry Hunsicker,
Agnes Fogo, and Elaine Solez
1999 Meeting - Protocol biopsies, chronic rejection, and viral diseases, clinical practice guidelines.
First conference supported by an NIH grant.
64. 1999 Meeting – Michael Kashgarian and Agnes
Fogo
1999 Meeting - Protocol biopsies, chronic rejection, and viral diseases, clinical practice guidelines.
First conference supported by an NIH grant.
65. 1999 Meeting – Glomerulitis Study Group with
Kiril Trpkov
1999 Meeting - Protocol biopsies, chronic rejection, and viral diseases, clinical practice guidelines.
First conference supported by an NIH grant. Glomerulitis study group.
66. 1999 Meeting – Agnes Fogo
1999 Meeting - Protocol biopsies, chronic rejection, and viral diseases, clinical practice guidelines.
First conference supported by an NIH grant. Glomerulitis study group.
67. 1999 Meeting – Larry Hunsicker,
Elaine Solez, and Agnes Fogo
1999 Meeting - Protocol biopsies, chronic rejection, and viral diseases, clinical practice guidelines.
First conference supported by an NIH grant. Glomerulitis study group.
68. 2001 Meeting – Larry Hunsicker,
Agnes Fogo, Kim Solez and Bob Colvin
2001 Meeting - AMR, donor biopsies, genomics, CAN, heart transplantation
78. 2003 Meeting –
Lorraine Racusen and Family
2003 Meeting - C4d, macrophages, tolerance, accommodation, immunodepletion
79. 2005 Meeting – Phil Halloran, Ginny Halloran,
Vido Ramassar
2005 Meeting - Genomics and molecular markers, B cells, chronic allograft injury with
elimination of CAN, establishment of criteria for chronic rejection.
80. 2005 – Janice McDonald, Charlene Hunter,
Banu Sis, Michele Hales
2005 Meeting - Genomics and molecular markers, B cells, chronic allograft injury with
elimination of CAN, establishment of criteria for chronic rejection.
81. 2005 – Kim Solez and Banu Sis
2005 Meeting - Genomics and molecular markers, B cells, chronic allograft injury with
elimination of CAN, establishment of criteria for chronic rejection.
82. 2007 Meeting – Michele Hales and Eduardo
Martul
2007 Meeting - Protocol biopsies, transcriptome, mechanisms of rejection, ptc grading, new
total inflammation score; working groups for v-lesion, genomic integration, pancreas and
composite tissue rejection schemas
83. 2007 Meeting – Kunio Morozumi and Michael
Mihatsch
2007 Meeting - Protocol biopsies, transcriptome, mechanisms of rejection, ptc grading, new
total inflammation score; working groups for v-lesion, genomic integration, pancreas and
composite tissue rejection schemas.
84. 2007 Meeting – Banu Sis
2007 Meeting - Protocol biopsies, transcriptome, mechanisms of rejection, ptc grading, new
total inflammation score; working groups for v-lesion, genomic integration, pancreas and
composite tissue rejection schemas.
85. 2007 Meeting – Ian Gibson
2007 Meeting - Protocol biopsies, transcriptome, mechanisms of rejection, ptc grading, new
total inflammation score; working groups for v-lesion, genomic integration, pancreas and
composite tissue rejection schemas.
86. 2007 Meeting – Roz Mannon
2007 Meeting - Protocol biopsies, transcriptome, mechanisms of rejection, ptc grading, new
total inflammation score; working groups for v-lesion, genomic integration, pancreas and
composite tissue rejection schemas.
87. 2007 Meeting – Michael Mengel
2007 Meeting - Protocol biopsies, transcriptome, mechanisms of rejection, ptc grading, new
total inflammation score; working groups for v-lesion, genomic integration, pancreas and
composite tissue rejection schemas.
88. 2007 Meeting – Eduardo and Lorraine
2007 Meeting - Protocol biopsies, transcriptome, mechanisms of rejection, ptc grading, new
total inflammation score; working groups for v-lesion, genomic integration, pancreas and
composite tissue rejection schemas.
89. 2007 Meeting – Nikki Olson and
Kim Solez
2007 Meeting - Protocol biopsies, transcriptome, mechanisms of rejection, ptc grading, new
total inflammation score; working groups for v-lesion, genomic integration, pancreas and
composite tissue rejection schemas.
90. 2007 Meeting – Tori Sheldon, Nikki Olson and
Paula Blanco
2007 Meeting - Protocol biopsies, transcriptome, mechanisms of rejection, ptc grading, new
total inflammation score; working groups for v-lesion, genomic integration, pancreas and
composite tissue rejection schemas.
91. 2007 Meeting – Michael Mengel
2007 Meeting - Protocol biopsies, transcriptome, mechanisms of rejection, ptc grading, new
total inflammation score; working groups for v-lesion, genomic integration, pancreas and
composite tissue rejection schemas.
92. 2007 Meeting – Tori Sheldon and
Nikki Olson
2007 Meeting - Protocol biopsies, transcriptome, mechanisms of rejection, ptc grading, new
total inflammation score; working groups for v-lesion, genomic integration, pancreas and
composite tissue rejection schemas.
93. 2007 Meeting –Nikki Olson
2007 Meeting - Protocol biopsies, transcriptome, mechanisms of rejection, ptc grading, new
total inflammation score; working groups for v-lesion, genomic integration, pancreas and
composite tissue rejection schemas.
94. 2007 Meeting –Eduardo and
Lorraine and Richard Racusen
2007 Meeting - Protocol biopsies, transcriptome, mechanisms of rejection, ptc grading, new
total inflammation score; working groups for v-lesion, genomic integration, pancreas and
composite tissue rejection schemas.
95. 2007 Meeting – Dinner in Castle, Nikki Olson,
Tori Sheldon, and Bob Colvin
2007 Meeting - Protocol biopsies, transcriptome, mechanisms of rejection, ptc grading, new
total inflammation score; working groups for v-lesion, genomic integration, pancreas and
composite tissue rejection schemas.
96. 2009 Meeting – Jubilant Tori and Akshatha
Return to Edmonton!
2009 Meeting - Viruses, quality assurance, AMR in kidney, heart, and pancreas, liver allograft
accommodation, endothelial cells, surrogate markers. Working groups.
97. 2009 Meeting – Lorraine Racusen and Michael
Mengel
2009 Meeting - Viruses, quality assurance, AMR in kidney, heart, and pancreas, liver allograft
accommodation, endothelial cells, surrogate markers. Working groups.
98. 2009 Meeting – Mark Haas
2009 Meeting - Viruses, quality assurance, AMR in kidney, heart, and pancreas, liver allograft
accommodation, endothelial cells, surrogate markers. Working groups.
99. 2009 Meeting – Jubilant Dar, Akshatha and Tori
Head Back to Edmonton!
2009 Meeting - Viruses, quality assurance, AMR in kidney, heart, and pancreas, liver allograft
accommodation, endothelial cells, surrogate markers. Working groups.
100. 2011 Meeting – Larry Hunsicker, Agnes Fogo,
and Kim Solez
2011 Sensitized patient, C4d, isolated v-lesion, the future, genomics, glomerulitis, epithelial injury
/epithelial mesenchymal transformation, operational tolerance monitoring in liver grafts.
101. 2011 Meeting – Banu Sis Isolated V
2011 Sensitized patient, C4d, isolated v-lesion, the future, genomics, glomerulitis, epithelial injury
/epithelial mesenchymal transformation, operational tolerance monitoring in liver grafts.
102. 2013, 2015, and 2017 – Recent so you have
your own favorite images!
Kim Solez’s favorite image from Banff 2017 capturing the spirit of Banff!
103. Banff 2019 and 2021 will be in Pittsburgh, USA and
Banff, Canada. Banff 2019 will have a regenerative
medicine/tissue engineering themed pre-meeting.
New Kinnear Conference Center holding 470 people at the Banff Centre for Conferences!
104. From Kinnear Centre Where We Will Be in 2021 Can
See TransCanada Pipeline Pavilion out the Window!
Can see our original site for Banff 1991, 1993, and 1995 out the window!!
106. It Was Always the Intention that Banff Would
be Digital, Portable, Morphometric, AI Based.
Can see our original site for Banff 1991, 1993, and 1995 out the window!!
107. Banff Has Progressed As Far As It Can in the Low
Tech Route. Future Major Advances Will Require
High Tech Approaches: Digital Path /Artificial
Intelligence/Genomics/Regen Medicine.
109. AI and Pathology Came Together in April 2017 FDA
Approval of Digital Pathology for Primary Diagnosis
110. In 2018 the First Ever Digital Pathology and AI
Congress in New York City
111. I recruited Digital Pathology expert Yukako Yagi to
joint UAlberta/Univ. Pittsburgh position in early
1990s!
Now at Memorial Sloan Kettering, she was one of keynote speakers at
2018 Digital Pathology and AI Congress.
112. Almost Overnight Pathology Went From Having
the Worst Promotion of Any Specialty to the
Best. We became the Hollywood of Medicine!
113. Gone Are The Blood And Guts. Now Every Page
is Visually Appealing and Seductive!
114. Every Effort Is Made to be Reassuring and
Comforting.
“AI pathology is never going to
replace pathologists.”
“Nobody should feel threatened by
advances in computational pathology.”
“The integrative aspects of pathology,
the cognitive abilities of pathologists,
and the collective wisdom generated
over many years as a community
cannot be replaced by a machine.”
115. These statements are only true near term, not
forever:
“AI will really help enrich your ability to
practice pathology and improve your
ability to serve your patients.”
“AI is not here to remove pathologists
from the decision-making process.”
“(AI is) an exciting step forward in the
discipline of pathology – one that puts
pathologists at the very center of clinical
care and precision
therapeutics.”
116. Pathologists Will Remain Central Only So Long As They
Add Value To The Process. And about being replaced:
Bertalan Mesko - The Medical Futurist
states it correctly:
“AI will not replace physicians, but
physicians using AI will replace
physicians not using AI.”
117. All Five Reasons in this Online 2018 Article are
Unsupported & Incorrect:
Bertalan Mesko - The
118. All Five Reasons in this Online 2018 Article are
Unsupported & Incorrect:
Bertalan Mesko – The Medical Futurist incorrectly
states that:
1. AI cannot be empathetic.
2. AI cannot do nonlinear thinking.
3. Machines cannot interpret data.
“No robot or algorithm could clearly interpret complex, multi-
layered challenges – involving the psyche. While they will
provide the data, interpretation will always remain human
territory.”
https://medicalfuturist.com/5-reasons-artificial-intelligence-wont-replace-physicians
4. There will always be tasks like the Heimlich maneuver algorithms and
robots can never complete.
5. Human machine cooperation is the ultimate solution. There is
nothing better.
119. New Finnish Government AI course
www.elementsofai.com Says We Do Not Need to Fear AI
because Self Improvement Requires Human Help.
“… even if a system could optimize its own workings, it would keep
facing more and more difficult problems that would slow down its
progress, quite like the progress of human scientists requires ever
greater efforts and resources by the whole research community and
indeed the whole society, which the … entity wouldn’t have access
to. … human society still has the power to decide what we use AI
technology for. (With progress in AI we become)…better at controlling any
potential risks due to it.”
120. Machines Will Be Able to Create Their Own Models of
the World but Humans Will Want to Get a Word in
Edgewise!
https://www.theguardian.com/books/2018/jun/15/rise-of-the-machines-has-
technology-evolved-beyond-our-control-
121. Machines Will Be Able to Create Their Own Models of the
World but Humans Will Want to Get a Word in Edgewise!
"Google Translate was known for its humorous errors, but in 2016, the system
started using a neural network developed by Google Brain, and its abilities
improved exponentially. Rather than simply cross-referencing heaps of texts, the
network builds its own model of the world, and the result is not a set of two-
dimensional connections between words, but a map of the entire territory. In this
new architecture, words are encoded by their distance from one another in a mesh
of meaning – a mesh only a computer could comprehend."
• https://www.theguardian.com/books/2018/jun/15/rise-of-the-machines-has-technology-evolved-
beyond-our-control-
122. Fictional Worlds Presented to Sentient AI As Fact
Threaten Humanity’s Survival
AI Will be Sensitive to Lies About Itself
123. Fictional Worlds As Models of the Real World Exist
Already in 2018-2019 and Will Increase in Number and
Influence
124. YouTube channel www.youtube.com/user/kimsolez
explores pathologist/AI interaction and tissue
engineering pathology influence in the future. Rate
of subscription increased six fold in 2018!
New Kinnear Conference Center holding 470 people at the Banff Centre for Conferences!
125. Areas of shared interest for Kim Solez/Ishita Moghe
the subject of presentations in November 2018-
February 2019
• Medicine Before Medical School, Infectious Youth,
Agency, and Reimagining Future Communication: What If
the Secret of High Impact, Awesome Recruiting, and the
Fountain of Youth Have Been Hiding Right in Front of Us
All Along.
• Yuval Noah Harari, Fulfilled Reality, Multithreading,
Bucket Lists, and What We Will Use That Extra Intellect
for in the Future
• Precision Medicine
126. Do We Have Agency? Can We Make Change?
In Previous Eras It Took Years to Decades to
Effect Change Via Journal Articles and Books.
In Banff Classification, we are still
struggling with borderline changes after 27
years. Discussed with Leonard Cohen in
2005, became the song “Treaty” 11 years
later. Isolated v lesions discussed as
evidence for rejection for 6 years.
Interaction stylized documented, and
formal. Slow, but you knew who influenced
what.
127. In 2019 We Have Agency, But Proof Is Lacking Who
Influenced What. As Instances Accumulate Evidence
Becomes Convincing. Timeline 2 days to 6 months.
Much Faster than Before! Formal Documentation
Lacking. Three Examples. #1
Instance #1 Human Cell Atlas Project (HCAP) at
ASN Meeting.
Oct. 29, 2017 “Blind-sided by the future”
message posted to Facebook complaining about
exclusion of HCAP from mainstream meetings.
Oct. 31, 2017 HCAP scientist and nephrologist
Benjamin Humphries appointed Chair of Program
Committee for 2018 ASN Meeting. March 31,
2018 YouTube video describing Moghe-Solez
paradox of exclusion of such subjects from
mainstream meetings,
https://www.youtube.com/watch?v=dAb6EpwpE
kM
August 2018 Aviv Regev plenary presentation on
HCAP at 2018 ASN meeting announced, in Kidney
News received in Sept.
128. What a great moment it was to hear Aviv
Regev’s ASN Plenary talk the end of October
2018 after all the anticipation and talk with her
afterward!
129. In 2019 We Have Agency, But Proof Is Lacking Who
Influenced What. As Instances Accumulate Evidence
Becomes Convincing. Timeline 2 days to 6 months.
Much Faster than Before! Formal Documentation
Lacking. Three Examples. #2
Instance #2 Sept 15th, 2018 Yuval Noah Harari Claims humans will
be stuck, all plot lines wrecked when machines do all crucial
decision making.
https://www.theatlantic.com/magazine/archive/2018/10/yuval-
noah-harari-technology-
tyranny/568330/?fbclid=IwAR2WjyHq_srFD4Zg_Wop-
3emHbWLpQRvtrgr5qW04cqRm_X8f1GpEzzYFw0
Sept 21, 2018 Our multithreading video points out humans will
adapt, culture could be many-fold better than today with
multithreading.
https://www.youtube.com/watch?v=wL2rL8LPfQM
Oct. 4, 2018 In his Wired interview Harari now says human
reaction to machine decision making is work in progress, no
predictions can be made! https://video.wired.com/watch/yuval-
harari-tristan-harris-humans-get-
hacked?fbclid=IwAR1soHWIpmVz8P9HITPzd5Bdl2mYOy-
nXOe272x-6Eh5ufKVet5XXp_RmQU
130. In 2019 We Have Agency, But Proof Is Lacking Who
Influenced What. As Instances Accumulate Evidence
Becomes Convincing. Timeline 2 days to 6 months.
Much Faster than Before! Formal Documentation
Lacking. Three Examples. #2
In his wired video interview Harari advises that individuals can accomplish very little by
themselves. They should join groups, causes, he says. That is the opposite of our experience
doing videos together where we seem to be accomplishing a lot without joining groups.
131. In 2019 We Have Agency, But Proof Is Lacking Who
Influenced What. As Instances Accumulate Evidence
Becomes Convincing. Timeline 2 days to 6 months.
Much Faster than Before! Formal Documentation
Lacking. Three Examples. #3
May 24, 2018. Directly contradicts author’s own
book from October 2017. July 20, 2018 video
supports same ideas
https://www.youtube.com/watch?v=a1QguDFMBM
8
https://medicalfuturist.com/5-reasons-artificial-intelligence-wont-replace-
physicians?fbclid=IwAR0QeJYTbP-HRCndFXvR5glr1AR2fdTVGfc1t6fO-i-EOZ1F_77oJtw7YB0
132. We Directly Contradicted the May 24 July 20th 2018
posts in series of videos from Aug. 20 to Oct 11th.
Bertalan Mesko - The
133. On October 22, 2018, 11 days after our last video,
Bertalan Mesko posted new video that agrees with us!
https://www.youtube.com/watch?v=hT0ly4pDSoY.
134. October 22 Bertalan Mesko video that agrees
with us does not mention us!
https://www.youtube.com/watch?v=hT0ly4pDSo
Y.
135. Taken together these three examples suggest our
videos are accomplishing major things, have agency.
Bertalan Mesko - The
136. Short time frame, days to weeks, in these effects
suggests a new model of science communication.
Bertalan Mesko - The
137. Images from Ishita Moghe Talk Gamification to
Incentivize Computer Data Entry November 22, 2018 .
Bertalan Mesko - The
138. Images from Ishita Moghe Talk Gamification to
Incentivize Computer Data Entry November 22, 2018 .
Bertalan Mesko - The
139. Images from Ishita Moghe Talk Gamification to
Incentivize Computer Data Entry November 22, 2018 .
Bertalan Mesko - The
140. Images from Ishita Moghe Talk Gamification to
Incentivize Computer Data Entry November 22, 2018 .
Bertalan Mesko - The
141. Images from Ishita Moghe Talk Gamification to
Incentivize Computer Data Entry November 22, 2018 .
Bertalan Mesko - The
142. Images from Ishita Moghe Talk Gamification to
Incentivize Computer Data Entry November 22, 2018 .
Bertalan Mesko - The
143. Images from Ishita Moghe Talk Gamification to
Incentivize Computer Data Entry November 22, 2018 .
Bertalan Mesko - The
144. Previously I Only Knew Students’ Thoughts About Course
Through Feedback Questionnaire, but in Dec. 2018
Spontaneous Positive Outpouring. Ishita Moghe Lectures
Seemed Like Only New Element to Account for This .
Bertalan Mesko - The
145. Medical Grand Rounds Presentation
February 1, 2019:
Seizing the Opportunity of
Technology and The Future of
Medicine
Kim Solez, MD & Ishita Moghe, BSc
CREATING A POSITIVE
MEDICAL FUTURE FOR
EVERYONE
147. My mentor Robert Heptinstall was immensely
pleased with the Winter Term students in Jan. 1973,
encouraged me to repeat program in future years.
148. Student-Driven Innovation
● Creation of ‘Nephrology Immersion’
(2018)
● Creation of the LABMP 590 Course
(2011-present)
○ Tissue-engineering pathology
○ Ethics of the future
149. Art Conveys Important Messages of Science -
Enhances Technology Acceptance
● Doctors’ Dining Room in 5B WCM
HSC after Lab moves to Hub?
● Future and All That Jazz
● Tuesday Night Poetry at the Nook
Café
150. The Future &
All That Jazz
Message
Dr. Rich Sutton’s Views
on AI Safety
Acceptance. Share power.
AI will compete and cooperate
with us just like other people,
except with greater diversity and
asymmetries.
Step 1: Lose your sense of
entitlement
Step 2: Include AIs in your circle
of empathy
152. We Could Eliminate All Disease and Still Have A
Terrible World!
● The challenge of friendly AI becomes just a small part of a
much larger challenge of creating a friendly world in which
humans still have lives of significance, human history is
retained and extended.
● We all need to be engaged in ensuring a positive outcome for
humanity. The future is ours to shape. We need to get busy
doing that!
● Part of the imagined future could be one
where all disease was eliminated but life
was intolerable. Another where the only
diseases are from bioterrorism.
153. 2045 is only 26
years from now.
Many of you will still
be working then.
What will medical
careers be like then?
● Man-made diseases
● Bioterrorism
● Human enhancement
● Social responsibility
154. • “It is the curse of humanity that it learns to tolerate even the most
horrible situations by habituation. Physicians are the natural
attorneys of the poor, and the social problems should largely be solved
by them.”
-Rudolf Virchow
Rudolf Virchow on the Social Responsibility of
Medicine
156. Digitization in Medicine Can Help Prevent
Burnout
● Pathology and AI came together
in April 2017 FDA approval of
digital pathology for primary
diagnosis
● (Cytology, Frozen Sections, and
Hematopathology were excluded
from approval.)
● Push Connect Care Epic/Beaker
to be the best of the best EHRs
● Rather than burden physicians,
EHRs in the future should
augment patient care
157. Taken together, the three examples
suggest our videos are accomplishing
major things, & that we have agency.
Do We Have Agency? Can We Make Change?