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JOINTS 1
Type
of
Joint
Synovial
allow movemnt
articul. surface cover by hyaline cartil.
type A cell = macrophage like
type B cell = produce protein
synovial = lubrication & nourishment
Non synovial
cartilaginous
fibrous
Arthritis
Osteoarthritis
Arthritis a/w infectious
Septic arthritis
TB arthritis
Arthritis a/w immuno
Arthritis a/w crystals
Osteoarthritis
Feature
Affect 80% of elderly
Degenerative joint disease
RF
Age (old cartilage repair worse)
Genetic
Obesity (40% incr. risk)
Occupation - repetitive use
Trauma
Patho
Progressive erosion of the joint
"Wear & tear" and aging
Change mechanical of cartilage
Cartilage degeneration
Incr. water & decr. proteoglycan
NON INFLAMMATORY process
Osteoarthritis
Osteophyte
Heberdenenlarge distal interphal.
Bouchardenlarge prox. interphal.
Morpho.
Chondromalacia & cartil. fibrillation
Exposure of subchondral bone plate
Bone sclerosis due to continuous erosion
Osteophyte formation
2ndary = synov. thicken., muscle atrophy
2ndary = joint deform., osteoporosis
Classes
Primary
idiopathic - affect elder
site = weightbearing joint
site = interphalangeal
2ndary
occur at any age
site = damaged joint
causes = trauma, gout
causes = RA, TB
Effect
Asymptomatic
Severe pain
Morning stiffness
Restricted movement
Compression of nerve root by osteophyte
Dx
Often hx & clinical is enough
Xray - very characteristic
Synovial fluid
aspirate
clear
bit raised cell count
Tx
Goals
relieve pain
maintain or restore function
delay progression
Start as with the simplest
Paracetamol (relieve pain)
NSAID (relieve pain)
Mild opiate - co-proxamol, codeine
Glucosamine (delay progression)
Wt loss (the only proven therapy)
Joint replacement therapy (90% satisfy)
JOINTS 1.mmap - 06/01/2010 - Mindjet

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Joints 1

  • 1. JOINTS 1 Type of Joint Synovial allow movemnt articul. surface cover by hyaline cartil. type A cell = macrophage like type B cell = produce protein synovial = lubrication & nourishment Non synovial cartilaginous fibrous Arthritis Osteoarthritis Arthritis a/w infectious Septic arthritis TB arthritis Arthritis a/w immuno Arthritis a/w crystals Osteoarthritis Feature Affect 80% of elderly Degenerative joint disease RF Age (old cartilage repair worse) Genetic Obesity (40% incr. risk) Occupation - repetitive use Trauma Patho Progressive erosion of the joint "Wear & tear" and aging Change mechanical of cartilage Cartilage degeneration Incr. water & decr. proteoglycan NON INFLAMMATORY process Osteoarthritis Osteophyte Heberdenenlarge distal interphal. Bouchardenlarge prox. interphal. Morpho. Chondromalacia & cartil. fibrillation Exposure of subchondral bone plate Bone sclerosis due to continuous erosion Osteophyte formation 2ndary = synov. thicken., muscle atrophy 2ndary = joint deform., osteoporosis Classes Primary idiopathic - affect elder site = weightbearing joint site = interphalangeal 2ndary occur at any age site = damaged joint causes = trauma, gout causes = RA, TB Effect Asymptomatic Severe pain Morning stiffness Restricted movement Compression of nerve root by osteophyte Dx Often hx & clinical is enough Xray - very characteristic Synovial fluid aspirate clear bit raised cell count Tx Goals relieve pain maintain or restore function delay progression Start as with the simplest Paracetamol (relieve pain) NSAID (relieve pain) Mild opiate - co-proxamol, codeine Glucosamine (delay progression) Wt loss (the only proven therapy) Joint replacement therapy (90% satisfy) JOINTS 1.mmap - 06/01/2010 - Mindjet