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Bone 4
- 1. BONE 4 Bone Tumour Intro Benign or malignant In children & teen = primary tumour In adult = secondary or m. myeloma Mets Carcinomas much common than sarcoma E.g. = breast, prostatic, bronchogenic, renal Complic. of mets Pain Patho. fracture Replacement of bone marrow Hypercalcemia Primary tumour Benign - more common in children & youth Malignant - older ppl Dx = clinical, radiological & pathological Types bone-producing tumour cartilge-producing tumour Bone forming Benign = osteoma Malignant = osteosarcoma If locally aggressive = osteoblastoma Osteoma gardner syndrome (multi) often craniofacial Osteoid osteoma young age, male painful (give aspirin) site = femur or tibia tx = resection of nidus Osteoblas. young age site = vertebral column pain not relieved by aspirin tx = resection Osteosarc. young & elderly site = end of long bone cause = sporadic, genetic effect = pain, fracture, mets spread = thru periosteum, blood X ray = codman's triangle, sunray tx = chemo & surgical resection Bone Tumour Cartil. forming Benign Osteochondroma Enchondroma Chondroblastoma Chondromyxoid fibroma MalignantChondrosarcoma Osteochondr. age < 20 multiple or single mushroom shaped projection site = metaphysis Onchondr. any age site = small bone of hand & feet arise from metaphysis well circumscribed Chondrosar. 2nd most common bone malign. mid age > 40 site = axial skeleton can be aggressive & erosive mets = lung, liver, kidney tx = only surgical poor prognosis Osteoclastoma adult (20-55) site = epiphyseal of long bone (knee) osteoclast-like giant cells locally aggressive tumour Ewing's Sarcoma Origin = neuroectodermal Age = children & young adult Site = medul. cav. in diaphysis of long bone Dx = Xray (onion skin) Tx = chemo + surgery Prognosis = very poor BONE 4.mmap - 06/01/2010 - Mindjet