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Ethics, Bioethics, and Moral Reasoning:
                                 How to Think Well in a Complex World




Jonathan Beever, Purdue University Department of Philosophy
What are we doing?




1.   Personal, Societal, and Professional Ethics
2.   Ethics vs. RCR
3.   Bioethics
4.   Arguments and Moral Reasoning
5.   Applying Moral Reasoning




                                                    © 2012 Jonathan Beever
What is Ethics?


1. Personal, Societal, and Professional Ethics


           What is ethics?
              the systematic study of the coherence
              and consistency of our moral beliefs.

               moral beliefs = our intuitions concerning
               right and wrong, good and bad, just and
               unjust.                                     The Subject
                                                           Society
               Intuitions? …                               Professions




                                                              © 2012 Jonathan Beever
What is RCR?


  2. Ethics vs. RCR



                   RCR vs. ethics education

RCR = Responsible Conduct         Ethics Education
of Research                       - Education in moral
- training in legal codes of         reasoning
    appropriate behavior          - “how to think critically
- “how not to get sued”              and ethically” model
    models




                                                                 © 2012 Jonathan Beever
What is RCR?


   2. Ethics vs. RCR



                           RCR vs. ethics education

                           Role of philosophy and policy in science education and
                           moral education
                                                                      The Hastings Center
                           The need (NIH and NSF)                     and The IU Center for Bioethics
NIH Guide 23.23 required that applications for              The responsible and ethical conduct of
institutional research training grants lacking a plan for   research (RCR) is critical for excellence, as well as
instruction in responsible conduct of research be           public trust, in science and engineering.
returned without review… (NIH 1994)                         Consequently, education in RCR is considered
                                                            essential in the preparation of future scientists and
                                                            engineers. (NSF 2009)



                                                                                                                    © 2012 Jonathan Beever
What is Bioethics?


3. Bioethics

      Hellegers:
      1. Rights and duties of patients and health professionals
      2. Rights and duties of research subjects and researchers
      3. Formulation of public policy guidelines for clinical care and biomedical research


                               Potter:
                               1. long-range environmental concerns
                               2. Prevention, not just therapy
                               3. Search for wisdom




                                                                                 © 2012 Jonathan Beever
Why care?


3. Bioethics


               df. Bioethics: The proactive study of the relationship between
               biotechnologies and “societal ethics,” or our codified moral beliefs.




                                                                              © 2012 Jonathan Beever
Why care?




 © 2012 Jonathan Beever
What issues?


3. Bioethics


           • Animals                 •   Health
           • Cloning                 •   Personalized Medicine
           • Biotechnologies         •   Nanotechnologies
           • Environment             •   Genomic revolution
           • Energy and              •   Genetic testing
             Climate                 •   Stem Cell research
           • Euthanasia              •   Policy issues



                          • Et cetera…




                                                                   © 2012 Jonathan Beever
Why Reason?


4. Arguments and Moral Reasoning

                         ARGUMENT – a set of statements (or propositions)
                         such that one of the statements is supposed to be
                         supported by the others.


Deductive –                           Inductive –                              Abductive – hypothetical
necessary inference                   probable inference                       inference from a fact to the
from population to                    from sample to                           truth of a premise.
sample.                               population.

1. All dice in this bag are A’s;   1. All dice in this particular           1. All dice in this bag are A’s;
2. all dice in this particular     random sample are A’s;                   2. all dice in this particular random
random sample are taken from       2. all dice in this particular random    sample are A’s;
this bag;                          sample are taken from this bag;          3. therefore, all dice in this particular
3. therefore, all dice in this     3. therefore, all dice in this bag are   random sample are taken from this
particular random sample are       A’s.                                     bag.
A’s.



                                                                                                         © 2012 Jonathan Beever
Why Reason?


4. Arguments and Moral Reasoning

             Are ethical arguments of the same sort as other arguments?
             Does moral reasoning work like other reasoning?
                         (what are we reasoning about?)
             Descriptive vs. Normative claims

               Taxonomy of Ethical Theories (non-exclusive)

               Deontological         Consequentialist      Pragmatic
               Rene Descartes        Jeremy Bentham        C.S. Peirce
               Immanuel Kant         John Stuart Mill      James Dewey
               John Rawls            G.E. Moore
               Thomas Scanlon        Peter Singer

          FMI – see http://plato.stanford.edu/entries/reasoning-moral/



                                                                            © 2012 Jonathan Beever
How to Decide?


4. Arguments and Moral Reasoning

                                                                        Top-down

                                                                                Principlism:
                                                                                1. Autonomy
                                                                                2. Non-maleficence
                                                                                3. Beneficence
                                    Moral                                       4. Justice
                                   Decision




           FMI – see Beauchamp and Childress, Principles of Biomedical Ethics



                                                                                     © 2012 Jonathan Beever
How to Decide?


4. Arguments and Moral Reasoning

                                                                              Top-down

                                                                                      Principlism:
                                                                                      1. Autonomy
                                                                                      2. Non-maleficence
                                                                                      3. Beneficence
                                          Moral                                       4. Justice
                                         Decision




   Bottom-up
     Casuistry


                 FMI – see Beauchamp and Childress, Principles of Biomedical Ethics



                                                                                           © 2012 Jonathan Beever
How to Decide?


4. Arguments and Moral Reasoning

                                                                              Top-down

                                                                                      Principlism:
                                                                                      1. Autonomy
                                                                                      2. Non-maleficence
                                                                                      3. Beneficence
                                          Moral                                       4. Justice
                                         Decision




                                                      Reflexive Equilibrium

   Bottom-up
     Casuistry


                 FMI – see Beauchamp and Childress, Principles of Biomedical Ethics



                                                                                           © 2012 Jonathan Beever
What to Decide?


5. Applying Moral Reasoning


               1. Pharmacogenomic testing
               2. End-of-life care for PVS patient
               3. Animal Testing on GMO Mice
               4. ….

     How are we to best apply ethical theory and moral reasoning to real-world cases?



                                    Questions?


       Jonathan Beever, beeverj@purdue.edu
                                                                               © 2012 Jonathan Beever

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J.Beever Purdue University - Bioethics

  • 1. Ethics, Bioethics, and Moral Reasoning: How to Think Well in a Complex World Jonathan Beever, Purdue University Department of Philosophy
  • 2. What are we doing? 1. Personal, Societal, and Professional Ethics 2. Ethics vs. RCR 3. Bioethics 4. Arguments and Moral Reasoning 5. Applying Moral Reasoning © 2012 Jonathan Beever
  • 3. What is Ethics? 1. Personal, Societal, and Professional Ethics What is ethics? the systematic study of the coherence and consistency of our moral beliefs. moral beliefs = our intuitions concerning right and wrong, good and bad, just and unjust. The Subject Society Intuitions? … Professions © 2012 Jonathan Beever
  • 4. What is RCR? 2. Ethics vs. RCR RCR vs. ethics education RCR = Responsible Conduct Ethics Education of Research - Education in moral - training in legal codes of reasoning appropriate behavior - “how to think critically - “how not to get sued” and ethically” model models © 2012 Jonathan Beever
  • 5. What is RCR? 2. Ethics vs. RCR RCR vs. ethics education Role of philosophy and policy in science education and moral education The Hastings Center The need (NIH and NSF) and The IU Center for Bioethics NIH Guide 23.23 required that applications for The responsible and ethical conduct of institutional research training grants lacking a plan for research (RCR) is critical for excellence, as well as instruction in responsible conduct of research be public trust, in science and engineering. returned without review… (NIH 1994) Consequently, education in RCR is considered essential in the preparation of future scientists and engineers. (NSF 2009) © 2012 Jonathan Beever
  • 6. What is Bioethics? 3. Bioethics Hellegers: 1. Rights and duties of patients and health professionals 2. Rights and duties of research subjects and researchers 3. Formulation of public policy guidelines for clinical care and biomedical research Potter: 1. long-range environmental concerns 2. Prevention, not just therapy 3. Search for wisdom © 2012 Jonathan Beever
  • 7. Why care? 3. Bioethics df. Bioethics: The proactive study of the relationship between biotechnologies and “societal ethics,” or our codified moral beliefs. © 2012 Jonathan Beever
  • 8. Why care? © 2012 Jonathan Beever
  • 9. What issues? 3. Bioethics • Animals • Health • Cloning • Personalized Medicine • Biotechnologies • Nanotechnologies • Environment • Genomic revolution • Energy and • Genetic testing Climate • Stem Cell research • Euthanasia • Policy issues • Et cetera… © 2012 Jonathan Beever
  • 10. Why Reason? 4. Arguments and Moral Reasoning ARGUMENT – a set of statements (or propositions) such that one of the statements is supposed to be supported by the others. Deductive – Inductive – Abductive – hypothetical necessary inference probable inference inference from a fact to the from population to from sample to truth of a premise. sample. population. 1. All dice in this bag are A’s; 1. All dice in this particular 1. All dice in this bag are A’s; 2. all dice in this particular random sample are A’s; 2. all dice in this particular random random sample are taken from 2. all dice in this particular random sample are A’s; this bag; sample are taken from this bag; 3. therefore, all dice in this particular 3. therefore, all dice in this 3. therefore, all dice in this bag are random sample are taken from this particular random sample are A’s. bag. A’s. © 2012 Jonathan Beever
  • 11. Why Reason? 4. Arguments and Moral Reasoning Are ethical arguments of the same sort as other arguments? Does moral reasoning work like other reasoning? (what are we reasoning about?) Descriptive vs. Normative claims Taxonomy of Ethical Theories (non-exclusive) Deontological Consequentialist Pragmatic Rene Descartes Jeremy Bentham C.S. Peirce Immanuel Kant John Stuart Mill James Dewey John Rawls G.E. Moore Thomas Scanlon Peter Singer FMI – see http://plato.stanford.edu/entries/reasoning-moral/ © 2012 Jonathan Beever
  • 12. How to Decide? 4. Arguments and Moral Reasoning Top-down Principlism: 1. Autonomy 2. Non-maleficence 3. Beneficence Moral 4. Justice Decision FMI – see Beauchamp and Childress, Principles of Biomedical Ethics © 2012 Jonathan Beever
  • 13. How to Decide? 4. Arguments and Moral Reasoning Top-down Principlism: 1. Autonomy 2. Non-maleficence 3. Beneficence Moral 4. Justice Decision Bottom-up Casuistry FMI – see Beauchamp and Childress, Principles of Biomedical Ethics © 2012 Jonathan Beever
  • 14. How to Decide? 4. Arguments and Moral Reasoning Top-down Principlism: 1. Autonomy 2. Non-maleficence 3. Beneficence Moral 4. Justice Decision Reflexive Equilibrium Bottom-up Casuistry FMI – see Beauchamp and Childress, Principles of Biomedical Ethics © 2012 Jonathan Beever
  • 15. What to Decide? 5. Applying Moral Reasoning 1. Pharmacogenomic testing 2. End-of-life care for PVS patient 3. Animal Testing on GMO Mice 4. …. How are we to best apply ethical theory and moral reasoning to real-world cases? Questions? Jonathan Beever, beeverj@purdue.edu © 2012 Jonathan Beever

Editor's Notes

  1. Potter, Van Rensselaer. (1971).Bioethics: Bridge to the Future. NewYorK: Prentice-Hall.
  2. Willful Modulation of Brain Activity in Disorders of ConsciousnessMartin M. Monti, Ph.D., Audrey Vanhaudenhuyse, M.Sc., Martin R. Coleman, Ph.D., Melanie Boly, M.D., John D. Pickard, F.R.C.S., F.Med.Sci., LuabaTshibanda, M.D., Adrian M. Owen, Ph.D., and Steven Laureys, M.D., Ph.D.N Engl J Med 2010; 362:579-589February 18, 2010.Proc NatlAcadSci U S A. 1980 December; 77(12): 7380–7384.Genetic transformation of mouse embryos by microinjection of purified DNA.J W Gordon, G A Scangos, D J Plotkin, J A Barbosa, and F H Ruddle.Springer, J.A., J. Beever, N. Morar, J. Sprague, M. Kane. Ethics, Provacy, and the Future of Genetic Information in Healthcare Information Assurance and Security. In Information Assurance and Security Ethics in Complex Systems: Interdisciplinary Perspectives. M. Dark ed. 2010. ISBN: 978-1-61692-245-0 (hardcover)