The document describes the Indian Scale for Assessment of Autism (ISAA), an objective assessment tool used to diagnose autism in India. ISAA consists of 40 items across 5 domains that are rated on a 5-point scale to assess characteristics of autism. It is administered through observation, informant interview, and testing interactions with the individual. Scoring involves assigning percentages to indicate the frequency and intensity of behaviors, with higher scores suggesting greater impairment and dependency. ISAA provides a standardized way to evaluate autism symptoms and severity in individuals.
Specific learning disorder - reading disorder, mathematics disorder, and disorder of written expression and learning disorder NOS .
neurodevelopmental disorder produced by the interactions of genetic and environmental factors that influence the brain's ability to perceive or process verbal and nonverbal information efficiently.
Autism Spectrum Disorder (ASD) previously known as pervasive developmental disorder is a childhood disorder characterized by lack of communication skills and social interactions resulting in social withdrawal
Specific learning disorder - reading disorder, mathematics disorder, and disorder of written expression and learning disorder NOS .
neurodevelopmental disorder produced by the interactions of genetic and environmental factors that influence the brain's ability to perceive or process verbal and nonverbal information efficiently.
Autism Spectrum Disorder (ASD) previously known as pervasive developmental disorder is a childhood disorder characterized by lack of communication skills and social interactions resulting in social withdrawal
Pervasive developmental disorder are characterized by severe and pervasive impairment in several areas of development: reciprocal social interaction skills, communication skills, or the presence of stereotyped behavior, interests, and activities.
Pervasive developmental disorder are characterized by severe and pervasive impairment in several areas of development: reciprocal social interaction skills, communication skills, or the presence of stereotyped behavior, interests, and activities.
Autism is a complex developmental condition that typically appears during early childhood and is characterised by difficulties in social interaction, communication, restricted and repetitive interests and behaviours, and sensory sensitivities. It is called a ‘developmental’ condition because symptoms of autism generally appear in the first two years of a child’s life. It is called a ‘spectrum’ disorder because it is most influenced by different combinations of genetic and environmental factors and affects people differently and to varying degrees. Each autistic person has a set of strengths and challenges that are distinct from any other autistic person and the way (s)he/she learns, thinks or solves problems can range from highly skilled to severely challenged. ASD may occur in persons across all ethnic, racial, and economic groups.
This presentation was developed for a staff training day for Rainbow Nursery, Tel Aviv to support staff in developing their understanding of working with children with special and additional needs. It is appropriate for anyone working in early years and delivering the EYFS
A collection of information about Autism Spectrum Disorder definition,symptoms,therapies,last researches about behavioral analysis and a comaparaison between signs in children ,adolescents and adults
Signs Your Child Might Be Autistic - How to Treat Them.pptxLisa Kent
The diagnosis of ASD can bring in a lot of emotions and difficulties for your child and your family. Therefore, it is essential to seek support from the right people to help your child manage their condition. The autism support workers expose the children to various therapies, including positive behaviour support, incidental teaching, applied behaviour analysis, etc., which can help your child better adjust to his environment and have a normal life.
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Autism is a disease spectrum comprising 4 disorders manifested by disturbed social, emotional and intellectual abilities of a child. This presentation is a brief description of characteristics , problems and management of of an autistic child.
Prix Galien International 2024 Forum ProgramLevi Shapiro
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- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
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- GENE THERAPY
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- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
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Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
1. INDIAN SCALE FOR
ASSESSMENT OF
AUTSIM (ISAA)
TEST
NATIONALINSTITUTEFORTHEMENTALLYHANDICAPPED
AnISO9001:2000Institution
MANUAL
(Divyangjan)
TEST
NATIONALINSTITUTE FOR THE MENTALLY HANDICAPPED
An ISO 9001: 2000 Institution
MANUAL
INDIAN SCALE FOR
ASSESSMENT OF AUTSIM (ISAA)
(Divyangjan)
2. DescriptionOf TheTool
Domain-I SocialRelationshipand Reciprocity
Domain-II EmotionalResponsiveness
Domain-III Speech-Language and Communication
Domain-IVBehaviour Patterns
Domain-VSensoryAspects
ISAA is an objective assessment tool for persons with autism which uses observation, clinical
evaluation of behaviour, testing by interaction with the subject and also information supplemented by
parents or caretakers in order to diagnose autism. ISAA consists of 40 items rated on a 5-point scale
ranging from 1 (never) to 5 (always). The 40 items of ISAA are divided under six domains as given
below.
Individual with autism do not interact with other people. They remain socially unresponsive, aloof and
may have difficulty in understanding another person's feelings, such as pain or sorrow. The have
significant problems in use of body language and nonverbal communication, such as eye contact, facial
expressions, andgesturesandestablishingfriendshipswithchildrenofthesameage.
Individuals with autism do not show the expected feelings in a social situation. Emotional reactions are
unrelated to the situation and may show anxiety or fear which is excessive in nature without apparent
reason.Theymayengageinself-talkthatisinappropriatefor theirageandmaylackfearofdanger.
Individuals with Autism will have problems in speech development. They find it difficult to express
their needs verbally and nonverbally and may also have difficulty in understanding the non verbal
language of others. People with autism often, have echolalia and may repeat a word, phrase or sentence
outofcontext.
Individuals with autism may engage in self –stimulatory behaviour in the form of flapping of hands or
using an object for this purpose. They insist on following routines, sameness and may resist change.
Someautisticchildrenmayberestlessandexhibitaggressivebehaviour.
A majority of autistic people are either hyper or hypo sensitive to light, sound, smell and other external
stimulation. They may ignore objects or become obsessed by them or they may watch those objects very
intently or act as if they are not even there. Some autistic children explore their environment by smelling,
touchingor tastingobjects.
Indian Scale for Assessment of Autism
1 Test Mannual
3. Domain-IVCognitiveComponent
Guidelinesfor TestAdministration
Observation
Individuals with autism may lack attention and concentration. They do not respond to instructions
promptly or respond after a considerable delay. On the other hand individuals with autism may also have
special or unusual ability known as, savant ability in some areas like reading, music, memory and artistic
abilities.
Advance preparationof theexaminer
The examiner should have a through familiarity with the test items, test materials, recording and scoring.
Guidelines for rating ISAAshould be adhered. It is advisable to practice test administration using CD to
understandsubtlecuesandobservingexamineebehaviour.
Each item of ISAA is to be assessed and a rating is to be given based on the intensity, duration and
frequencyof thecharacteristics.
a) TestingConditions
ISAA must be administered under standard testing conditions and testing methods as given
below.
Ø Person's physiologicalcondition(fatigue,sleepandstatechanges)
Ø Comfortleveloftheperson beingtested
Ø Periods offearor oppositionalityintheperson beingtested
Ø Qualityof informant'sverbalizations
Ø Considerationof environmentalandculturalinfluences
Ø Congenialenvironmentandrapportwhileinterviewinginformants
Ø Understandingindividualdifferences
Ø Thoroughfamiliaritywiththetestcontentandprocedures
Ø Flexibilityoftheexaminer
b) MethodofAssessment
i) Observation
ii) Informantinterview
iii) Testing
Thetestershould focus on theindividualbeingtestedforthefollowingaspects.
Ø Interactionwiththecaregiverandothers
2
Test Mannual
4. Ø Qualityof socialresponsiveness intermsof duration,reciprocity.
Ø Interestinpeopleandobjects
Ø Communication
Ø Use ofsensory modalities
Ø Comfortlevelordistress inrelationtoothers
Ø Inappropriatebehaviours
For example, testing for “Poor eye contact” should be assessed by observing the individual to see how
frequently she/he makes eye contact, how long eye contact is maintained and its appropriateness to the
age of the person as well as cultural norms. This information should be supplemented by seeking
informationfromtheinformantsthroughinterview.
Reliable information from the informant, across different settings, is crucial for proper evaluation. For
example, while testing for delayed response time, use Picture Books/Blocks and ask the child to show
some object/thing/fruit in a picture book or natural surrounding. Observe if the child is responding after
a delay or repeated instructions or prompts are required to elicit a response.Ask for the names or uses of
objectsor differencesbetweenobjectsdependingon theageofthechild.
b)TestingTime
Assessment ofpersons withautismmaytake20-30 minutes
d) Materials
Theassessmentkitshould comprisethefollowingitems.
Interview
13 Watch
14 Hand bell
15 Paper and crayons
16 Blocks
17 Squeezer – Cat / Dog
18 Fruits/Vegetable toys
19 Box
20 Bottle and pellets
21 Mirror
22 Shape sorter
23 Slide with a rolling ball
24 Musical toys
1 Car
2 Ball (different sizes)
3 Doll (different types)
4 Rattle
5 Picture book
6 Peg board with rings
7 Sorting board
8 Cup
9 Spoon
10 Beads with a string
11 Colour card/Board
12 Key
3 Test Mannual
5. Scoring System
ISAAshould bescoredasperthescoringsystemgivenbelow.
Each of the 40 test items is to be rated on 5 categories, out of which one is to be checked. These are
further quantified by providing percentages to indicate the frequency, degree and intensity of
behavioural characteristics that are observed. The categories along with the percentages assigned are as
follows:
Rarely (Up to 20%) indicates that the person exhibits this behaviour pattern for up to 20% of the time.
Thisscoreis normalfor theirageandsocio-educationalbackground-Score1.
Sometimes (21 – 40 %) indicates that the person exhibits this behaviour pattern for 21%-40 % of the
time. Some of these behaviours may be a cause for attention and concern, but by and large they may be
consideredwithinnormallimitsfor theirageandsocio-educationalbackground.
Person iscompletelyindependentinactivitiesofdailylife-Score 2.
Frequently (41 – 60%) indicates that the person exhibits this behaviour pattern for 41% - 60% of the
time. These behaviours occur with such frequency and regularity that they interfere with the persons'
functioningindailylife.Behaviouratthislevelwillbedefinitelydisabling.
Person maybeabletoperformactivitiesofdailylifewithminimumassistance-Score 3.
Mostly (61– 80 %) indicates that the person exhibits this behaviour pattern for 61% - 80 % of the time.
The given behaviour may occur without any discernible stimulus. The behaviour under consideration
occursso regularlythatitsignificantlyhamperstheperson inperformingdailyactivities.
Person needsassistanceinactivitiesofdailylife-Score 4.
Always (81% - 100 %) indicates that the person exhibits this behaviour pattern almost all the time, so
much so that it would be considered a major handicap.The behaviour shown is seldom appropriate to the
givensituation.
Person iscompletelydependentonactivitiesof dailylife-Score 5.
Theminimumscorethat can beobtained is 40.
Themaximumscorethat canbeobtained is 200.
4
Test Mannual
6. Indian Scale for Assessment of Autism
I SOCIALRELATIONSHIPAND RECIPROCITY
1.Pooreyecontact
Individuals with autism avoid looking people in the eye. They are unable to maintain eye
contact as expected for a given age or required of social norms. Eye contact may be unusual such
as gazingfortoolongon onespot or lookingsideways.
2.Lacksocialsmile
Individuals with autism do not smile when meeting people or in reciprocation. A smile that
reflectssocialresponse andrecognitioncannotbeelicitedfromsuch persons.
When the child enters see how he/she reacts to strangers. Whether smiles or not. How he
responds tofriendlyoverturessuch asasmileor ahandshake.
3.Remainaloof
Individuals with autism may remain aloof, self-absorbed, withdrawn, and not responsive to
people or environment. They seem to be preoccupied with their self and be away from the social
world around. They hardly respond to, or initiate contact with others. There is lack of age
appropriatepretendplay.
Ask the child if he has friends, whom he likes at home or what he likes to eat etc. Observe how
responsivethechildistoyou whenyou interact.
4.Do not reachout to otherpersons
Individuals with autism do not interact with other people and remain socially unresponsive.
They do not initiate, seek, or respond to social interactions. They may not respond to their name,
andeveniftheydo,itmaynotbeappropriate.
Check if the child/individual takes any initiative to elicit a response or reaction from others.
Does he respond to his name or not and how he reacts when you try to engage him in a social
interaction.
5.Inability to relatetopeople
Individuals with autism do not initiate contact with others and may not relate to people as
expected of their age. Reminders are required to attune the individuals with autism to the
presence of people and social situations. Persistent effort is required to get their attention. They
seem to be indifferent and impersonal in their interactions with others, if at all contact is
established.
5 Test Mannual
7. 6.Inability to respond to social/environmentalcues
Individuals with autism are not responsive to social and environmental demands or
expectations. They show behavior which is not synchronous with the demands/ requirements of
thesocialenvironment.
Ask if the child behaves appropriately or not in keeping with what is expected in a given social
situation and also find out whether the child behaves appropriately when parents take him/her to
visitfriendsor relatives,orbehavesproperlyinamarket.
7.Engageinsolitaryand repetitiveplayactivities
Individuals with autism play alone most of the time or prefer solitary activities. They avoid
playingwithothersandmaynotengageingroup orientedactivitiesor tasks atall.
Ask if the child plays in a group with other children or he plays alone with some object or
materialrepetitively.
8.Inability to taketurns insocialinteraction
Individuals with autism do not comprehend the significance of taking turns in reciprocal
interactionwithothers.Theydonotwaituntiltheirturncomesortheothers' turnends.
Check if the child can play with a ball by taking turns with someone or can he play bat and ball
with someone which requires turn taking and whether he waits for his turns when talking to
others.
9.Do not maintainpeerrelationships
Individuals with autism do not develop age appropriate friendships. They may not engage in age
appropriate peer interactions or maintain peer relationships as is socially expected. Autistic
persons appeartofinditdifficulttounderstandsocialrulesandtoconformtosocialboundaries.
Ask if the child plays with children of his age, what he plays with them, and how well he mixes
withthemor bonds withthem.
10.Inappropriateemotionalresponse
Persons with autism do not show the expected feeling in a social situation. They express
inappropriate emotional responses like laughing when scolded or spanked and inappropriate
degree of response like excessive crying or laughing that is unwarranted. Emotional reactions
are unrelated to the event or situation around the individual. They may show unpredictable shift
inemotions,thatis, theymaybecomeexcited,agitatedor distressedfor no apparentreason.
11.Show exaggeratedemotions
Persons with autism may show anxiety or fear which is excessive in nature and which may be
II EMOTIONALRESPONSIVENESS
6
Test Mannual
8. triggered off without an apparent reason.At times, it may be exaggerated or atypical.The autistic
individual may show extreme fear of innocuous objects or events leading to uncontrolled
behavior.
12.Engage inself-stimulatingemotions
Individuals with autism may engage in self talk that is inappropriate for their age. The autistic
individual may smile to self without any apparent reason. Check if the child talks to self or
laughsor smilesor whines for no apparentreason.
13.Lackfearofdanger
Persons with autism may not show fear of hazards or dangers which others of the same age
would show or know.
14.Excitedoragitatedforno apparentreason
Persons with autism may show excitement, over activity or agitation that is both excessive and
unwarranted. Theautisticchildmovesaroundwithbrisk energy andmaybedifficulttocontrol.
15.Acquiredspeechand lostit
Speech development is not age-appropriate.The autistic individual may have developed speech,
butlostitsubsequently.50%of autisticmaybemute.
16.Difficultyinusing non-verbal language orgestures to communicate
Persons with autism find it difficult to express their needs non-verbally and may also have
difficulty in understanding the non-verbal language of others. Instead of gesturing or pointing,
theymayleadotherstothedesiredobjectbydraggingorpullingthelatter'shand.
Arrange Cup, Doll, Car, Spoon, and Key in a row and ask the child to point to one of the objects.
Keeptwoorthreeobjectsatatimetocheckifthechildcanpointtoobjects.
17.Engage instereotypedand repetitiveuse oflanguage
Persons with autism may repeat a word, phrase or sentence out of context. They repeat the same
statementmanytimes.
18.Engage inecholalicspeech
Persons with autism may repeat or echo questions or statements made by other people.They may
notunderstandthattheyhavetoanswerthequestions.
Observeifthechildis repeatingwhatyousaideitherthewholeor apartofwhatyousaid.
III SPEECH-LANGUAGEAND COMMUNICATION
7 Test Mannual
9. 19.Produceinfantilesqueals orunusual noises
Persons with autism may squeal, make bizarre noises and produce unintelligible speech like
sounds.Theymayproducespeechlikesounds whichlackmeaning.
20.Unable to initiateorsustain conversationwith others
Persons withautismmaynotbeabletoinitiateor sustainconversationwithothers.
Check if the child can meaningfully respond to a series of questions or maintain a dialogue for
adequatetime.
21.Use jargon ormeaningless words
Persons withautismmayusestrangeormeaninglesswords whichconveynomeaning.
22.Uses pronoun reversals
Persons with autism may show difficulty in the use of pronouns. They frequently reverse
pronouns suchas“I”for “You”.
23.Unable to grasp pragmaticsof communication(realmeaning)
Persons with autism have difficulty in understanding the true intent of speech of others. They
may not understand the pragmatics of speech communication. For example, When somebody
asks them “Can you tell the time?, they may say 'Yes” and stop. Check if the person understands
humorandsarcasm.
24.Engage instereotypedand repetitivemotormanners
Persons with autism may engage in self-stimulatory behavior in the form of flapping of hands or
fingers,body rockingor using anobjectfor thispurpose.
25.Show attachmentto inanimateobjects
Individuals with autism may be staunchly attached to certain inanimate objects which they insist
on keepingwiththemselvessuch asstring,rock,pen,stick,toy,bottleandthelike.
Keep all the objects and check if the child shows attachment to inanimate object/s. This can be
seen if he likes to play with one object consistently and seems very much attached to it and shows
resistanceandtempertantrumswhenthatobjectis takenaway.
26.Show hyperactivity/restlessness
IV BEHAVIOUR PATTERNS
8
Test Mannual
10. Individuals with autism may be restless with boundless energy which makes it difficult for
otherstocontrolthem.Thehyperactivityinterfereswiththeirlearningandperformanceof tasks.
27.Exhibitaggressivebehaviour
Persons with autism may show unprovoked aggression and socially inappropriate behavior such
as hitting,kickingandpinching.
28.Throw tempertantrums
Individuals with autism may show temper tantrums in the form of head banging, screaming, and
yellingetc.Such behaviorsareemittedwhenfrustrated.
29.Engage inself-injurious behaviour
Persons with autism may indulge in self-injurious behaviors like biting, hitting or mutilating
self.Suchindividualshavetobeconstantlysupervisedtopreventtheminjuringthemselves.
30.Insist on sameness
Persons with autism may resist change in their routine and insist that things be the same as they
were. Such individuals may insist on continuing the same activity and it would be very difficult
to distract them from such repetitive activities. Any change in the schedule leads to frustration
and temper tantrums. Thus, persons with autism show a degree of rigidity in their adherence to
routineandaccustomedways.
Check if the child wants to sit at the same place, reads the same stories, prefers the same route,
wants things to be kept in the same place, and wants the same schedule of activities in a
prescribedsequencealways.
31.Unusually sensitivetosensory stimuli
Persons with autism may react strongly to certain sounds, light, touch or tastes by closing their
ears, eyes or refusing to eat food of certain consistency. They may actively avoid certain sensory
stimuli.
Ring the bell or any sound making object to see how the child reacts. Check if he is finding the
sound aversive or distressing or if he closes his ears. This is for auditory stimuli. Check how the
childreactstoyour touch.Observe how thechildreactstobrightilluminationordarkness.
32.Stareintospaceforlongperiodsof time
Persons with autism may stare at some distant spot or space for long periods of time. They seem
V SENSORYASPECTS
9 Test Mannual
11. tobeunawareofsurroundings whenthus occupied.
33.Difficultyintrackingobjects
Persons with autism may have difficulty in tracking objects or persons in motion. They are
unabletofolloworfixtheirgazeonmovingobjectsorpersons for therequiredperiodoftime.
Throw the ball or rattle and see if the child tracks it or not. Veer a car and move it around or spin
thetopandcheckifthechildislookingatitasittwirlsandmovesawayor not.
34.Has unusual vision
Persons with autism may be able to observe tiny details which may not be apparent to others.
Such individuals focus their attention on some insignificant part of an object that is generally
ignoredbyothers.
Check if the child is looking at some miniscule part of the object or toy or watching from the
cornersof his eyesor brings objectsveryclosetotheeyesandstares.
35.Insensitive to pain
Persons with autism may hardly react to pain. They seem not to be distressed or cry when hurt.
Theyseemtohavehighthresholdsfor pain.
36.Respond to objectsunusually by smelling,touching ortasting
Individuals with autism may go around exploring their environment by smelling, touching or
tastingobjects. Someof themmaynotshow appropriateuseofobjectsortoys.
Keep all the objects and observe if the child is smelling, touching or tasting the objects or if he is
using theobjectsappropriately.
37.Inconsistent attentionand concentration
It is difficult to arouse the attention of individuals with autism. They do not concentrate, and if
they do, then it may not be on relevant aspects of the object or event. As a result of this, they may
beinconsistentintheirresponse.
Ask thechildtoputthepegsontheboardorsortthe pieces and put them in their right places on
the sorting board or fill the bottle with the beads or string the beads in a twine. Check if the child
canattendandconcentrateon thetask.
38.Delayedresponse time
Persons with autism do not respond to instructions promptly or respond after a considerable
VI COGNITIVE COMPONENT
10
Test Mannual
12. delay.Quickresponse toinstructionsishardlyevertobeexpected.
Show picture books/blocks and ask the child to show some object in a picture book. Observe if
the child is responding after a delay or with repeated instructions. Ask for the name of things or
objectsoritsuses or differencesbetweenobjectsdependingon theageofthechild.
39.Unusual memory
Persons with autism may show memory for things which most of the individuals would have
long forgotten. Some of them have exceptional ability to remember things from the distant past.
Check if the child recognizes people he met long time back or remembers the routines taken or
placesvisitedordatesor timeorlocationsornamesofthingstoanextraordinaryextent.
40.Savant ability
Persons with autism may have special or unusual ability in some areas like reading early,
mathematical feats or artistic talent. Some of them may show superior ability, but in a restricted
fieldofinterest.
Validity: Validity of ISAAtest items was determined by correlating the individual item scores with the
total scores, all the items of the scale were significantly correlated with total scores at 0.001 level, except
oneitem(A40), namely'savantability'whichwas significantat0.5level.
Internal consistency reliability: Internal consistency reliability of ISAAwas computed using Cronbach
alpha. The alpha coefficient obtained was 0.93 (p<0.001) for autism group indicating high degree of
internalconsistency.
Inter-rater reliability : Inter rater reliability of ISAA was obtained using Pearson Product Moment
Correlation between two raters who independently administered and scored ISAA on 67 randomly
selected children (about 17% of the sample). Correlations between raters varied from 0.62 to 0.81 in
differentdomainswhichareequivalenttothosefound instandardtool,namely,CARS.
Test-Retest Reliability: In order to assess the Test retest reliability of ISAA, 120 subjects (30% of
sample) from autism group were retested after three months. Correlations ranged from 0.60 to 0.85 in
various domains and for the total score it was 0.83 (p<0.001). These results indicate that test-retest
reliabilityofISAAisgood.
Sensitivity and Specificity: Sensitivity and Specificity of ISAA was computed for investigating its
effectiveness in discriminating autistic and non autistic children as compared to CARS. Further,
Standardization oftheTool
11 Test Mannual
13. Receiver Operating Characteristic (ROC) curve analysis was carried out to assess the discriminant
power of ISAA, using these sensitivity and specificity levels at different cut offs. The ROC analysis also
confirmedthediscriminantabilityofISAA,AUC =0.931withSE=0.009atcutoff70.
Based on the ROC cut off score of 70, a diagnostic categorization of ISAA has been established which
aids in the interpretation of total ISAA scores. Using this cut off level, individuals falling below the
score of 70 are categorized as non autistic while those with score of 70 and above are categorized as
autistic.
To arrive at the taxonomy of ISAA, the scores of 376 children who scored 70 and above from autism
group wereanalyzed. Themeanscorewas found tobe106.09, rangebeing70.0to181.0as givenbelow.
Scores ranging from cut off score to mean score (70 to 106) has been classified as mild autism, scores
Norms
N Minimum Maximum Mean S.D
ISAA Total 376 70.0 181.0 106.09 23.5
from mean to Mean+ 2SD (106 to 153) as moderate autism and scores above mean + 2SD (> 153) as
severeautism,asindicatedbelow.
Norms of ISAA for Diagnosis of Autism
ISAA Scores Degree of Autism
< 70
70 to 106
107 to 153
> 153
Normal
Mild Autism
Moderate Autism
Severe Autism
12
Test Mannual
14. Percentage of Disability as per the score
Percentage (%)
Conclusion:
Indian Scale for Identification of Autism (ISAA) is a standardized tool with good psychometric
properties.Itis areliableandvalidtoolfor makingdiagnosisof persons withAutism.
Score
70
71-88
89-105
106-123
124-140
141-158
Above 158
40
50
60
70
80
90
100
13 Test Mannual
15. INDIAN SCALE FOR ASSESSMENT OF AUTISM
Name of the child:……………………. Gender:……….. Date:……………
D.O.B:……………………….. Age: …………… Examiner: …………….
Items
Rarely
Upto 20%
Score 1
Sometimes
21 – 40 %
Score 2
Frequently
41 – 60%
Score 3
Mostly
61- 80 %
Score 4
Always
81-100%
Score 5
I. SOCIAL RELATIONSHIPAND RECIPROCITY
1 Has poor eye contact
2 Lacks social smile
3 Remains aloof
4 Does not reach out to others
5 Unable to relate to people
6 Unable to respond to social/ environmental cues
7 Engages in solitary and repetitive play activities
8 Unable to take turns in social interaction
9 Does not maintain peer relationships
II. EMOTIONAL RESPONSIVENESS
10 Shows inappropriate emotional response
11 Shows exaggerated emotions
12 Engages in self-stimulating emotions
13 Lacks fear of danger
14 Excited or agitated for no apparent reason
III. SPEECH-LANGUAGE AND COMMUNICATION
15 Acquired speech and lost it
16 Has difficulty in using non-verbal language or
gestures to communicate
17 Engages in stereotyped and repetitive use of
language
18 Engages in echolalic speech
19 Produces infantile squeals/ unusual noises
20 Unable to initiate or sustain conversation with
others
National Institute for the
Mentally Handicapped
(Ministry of Social Justice &
Empowerment, Govt. of India)
An ISO 9001:2000 Institution
Manovikas Nagar
Secunderabad – 500 009
Directions:
Below are given 40 statements which are divided under six domains, please tick (√)
mark the appropriate rating for each item of the scale by observing the child and by
interviewing the parents in order to assess Autism
14
Test Mannual
16. Items
Rarely
Upto 20%
Score 1
Sometimes
21 – 40 %
Score 2
Frequently
41 – 60%
Score 3
Mostly
61- 80 %
Score 4
Always
81-100%
Score 5
21 Uses jargon or meaningless words
22 Uses pronoun reversals
23 Unable to grasp pragmatics of communication
(real meaning)
IV. BEHAVIOUR PATTERNS
24 Engages in stereotyped and repetitive motor
mannerisms
25 Shows attachment to inanimate objects
26 Shows hyperactivity/ restlessness
27 Exhibits aggressive behavior
28 Throws temper tantrums
29 Engages in self-injurious behavior
30 Insists on sameness
V. SENSORY ASPECTS
31 Unusually sensitive to sensory stimuli
32 Stares into space for long periods of time
33 Has difficulty in tracking objects
34 Has unusual vision
35 Insensitive to pain
36 Responds to objects/people unusually by
smelling, touching or tasting
VI. COGNITIVE COMPONENT
37 Inconsistent attention and concentration
38 Shows delay in responding
39 Has unusual memory of some kind
40 Has ‘savant’ ability
Classification No Autism
< 70
Mild Autism
70 to 106
Moderate Autism
107 to 153
Severe Autism
> 153
Total score
15 Test Mannual
17. Disha – Early Intervention & School Readiness
SchemeDescription
· Day care facility for children with NT disabilities in the age group of 0-10 years for at least 4-6
hours perdayfor abatchsize20
· Trainingandcounselingtochildrenandtheparentstoenablemainstreamingofchildren
· Professionalservicesbyspecialeducators,therapistsandcounselors
· Availabilityofoptionaltransportfacility
· Continuousevaluationof childrenandmappingofdevelopmentchart
· Assistanceandguidancefor admissiontoschools
· KPIs monitored shall be – PwD strength, LIG:Non LIG ratio, PwD development, PwD
mainstreaming,ParentCounselling
16
Set-up 1,55,000 Immediately after enrolment
Sustenance
Monthly
Recurring
4,500 per Differential PwD per month
Monthly for 3 months (min. PwD is
20% of batch size, i.e. 4)
4,500 per eligible PwD per month
(+1000 Transport allowance)
Monthly on 1:1 ratio for LIG:Non
LIG and All BPL
Vikaas - Day Care
SchemeDescription
· Day care facility for PwD above 10 years of age for at least 6 hours in a day (between 8 am – 6
pm)forabatchsize30
· Training and counseling to PwDs in the age group of 10+ years for enhancing interpersonal and
vocationalskills,besidesmainstreaming
· Professionalservicesbyspecialeducators,therapistsandcounselors
· Availabilityofoptionaltransportfacility
· Enablefamilymemberstofulfillotherresponsibilities
· Provision forsettingupWorkCenters
· KPIs monitored shall be – PwD strength, LIG:Non LIG ratio, PwD development, Gainful
employmentof PwD
Set-up 1,95,000 Immediately after enrolment
Sustenance
Monthly
Recurring
3,850 per Differential PwD per month
Monthly for 3 months (min. PwD is
20% of batch size, i.e. 6)
3,850 per eligible PwD per month
(+1000 Transport allowance)
Monthly on 1:1 ratio for LIG:Non
LIG and All BPL
Work Centre Rs. 25,000 to Rs. 1,00,000/- Case to case basis
Test Mannual
Schemes of The National Trust
18. Samarth – Respite Care Residential Scheme
SchemeDescription·
· Residential facilities including meals for orphans/abandoned, families in crises, destitute, BPL
andLIGPwDs inallagegroups forabatchsize30.
· Provision to shift an adult resident to GHARAUNDA if stay in Samarth exceeds 5 years and
PwD is anadult
· Professional services by special educators, therapists and counsellors for age-specific
vocationalandpre-vocationalactivities
· RO should own thelocationor itsshould beonaleaseof minimum5yearswithrenewableclause
· KPIs monitored shall be – PwD strength, LIG:Non LIG ratio, PwD registration with Niramaya
scheme,PwD development,GainfulemploymentofPwD, Inclusioneventsorganized
17
Set-up 2,90,000 Immediately after enrolment
Sustenance
Monthly
Recurring
Work Centre
7,000 per Differential PwD per month
Monthly for 3 months (min. PwD is
20% of batch size, i.e. 6)
7,000 per eligible PwD per month
Rs. 25,000 to Rs. 1,00,000/-
Monthly on 1:1 ratio for LIG:Non
LIG and All BPL
Case to case basis
GHARAUNDA – Group Home for Adults
SchemeDescription
· Residential facilities including meals and all other facilities for life long stay of adult PwDs (>18
yearsofage)forabatchsize20.
· Professional services by special educators, therapists and counsellors for age-specific
vocationalandpre-vocationalactivities
· RO should own the location or its should be on a lease of minimum 10 years with renewable
clause
· Provision of crisis fund per Gharaunda Centre to be maintained with the National Trust – INR
10,00,000/-
· KPIs monitored shall be – PwD strength, LIG:Non LIG ratio, PwD registration with Niramaya
scheme,PwD development,GainfulemploymentofPwD, Inclusioneventsorganized
Set-up 2,90,000 Immediately after enrolment
Monthly
Recurring
10,000 per eligible PwD per month
Monthly on 1:1 ratio for LIG:Non
LIG and All BPL
10,00,000/- On need basis
Work Centre
Crisis Fund
Rs. 25,000 to Rs. 1,00,000/- Case to case basis
Test Mannual
19. Niramaya – Health Insurance
SchemeDescription
· HealthInsurancefor PwDs underNTAct
· FullpremiumtobepaidbytheNationalTrust
· Benefits include surgery, hospitalization, OPD, medicines, dentistry, medical tests, therapies
etc.up toRs.1 Lakh
· No requirementof healthcheck-upor ageproof
· No barforgovernmentor privatehospitals/practitioners
· Enrollmentonmonthlybasis throughRegisteredOrganizations(RO)
· Facilitationthrough34regionalclaimcenters
· Annual enrolment fee for BPL Rs. 250/-, Non BPL Rs. 500/- and PwD with Legal Guardian
(Otherthannaturalparents)FREE.
· KPIs monitoredshallbe:turnaroundtimefortheapplication,Niramayastatusreport
18
Health Insurance 1,00,000 per PwD per year As and when PwD will claim
Gyan Prabha – Education Support
SchemeDescription
· EncouragePwDs topursue vocationaltraining/highereducation/professionalcourses
· Wide range of courses like medical, engineering, law, management and regular graduation and
post graduationcovered
· No ageor incomelimitfor eligibility
· Recurring fixed amount for the specified courses covering course fees, transportation, books,
OPEs (max10%)etc.on presentingproofs exceptOPE
· Funding shall be provided for maximum duration of course or till when course is completed by
PwD as applicable
· KPIs monitoredshallbe:turnaroundtimefortheapplication,GyanPrabhastatusreport
Test Mannual
Sustenance Depending on course structure:
Monthly, semester wise, trimester
wise or annually.
Graduation/ Post Graduation
Vocational Course
Transportation allowance
(for any course)
5,200 per PwD per month
2,000 per PwD per month
1,600 per PwD per month
20,000/- per PwD per annum
or actuals, whichever is less
20. Sahyogi – Care Associate Training
SchemeDescription·
· Creating a pool of skilled care associates through theoretical and on-the-job training to support
PwDs andtheirfamilies
· Two types of courses – Primary (3 months), Advanced (6 months) having both theory and
internship
· Parents and guardians are also eligible to apply for the courses. However, they shall not be
involvedininternshipperiodofcourse
· Meeting(s) for placement amongst families, institutions and trained care associates on a
quarterlybasis
· KPIs monitored shall be – trainee strength, trainee attendance, internship opportunities,
placement,RO visitstatusreport
19
Prerna – Marketing Assistance
SchemeDescription
· Funding forparticipationinfairsand/orexhibitionsatdistrict,state,regionalandnationallevel
· NTtosponsor up tofour eventsinafinancialyear
· Minimumparticipationof 51%PwDs inproductionofsaleableitems/articles
· An incentiveof 10%for RO on salesturnoververifiedbyOfficeofDC/DM/LLC/SocialWelfare
· NT shall also reimburse the expenses that ROs incurred in designing and publishing brochures
marketingtheproductspreparedbyPwDs
· KPIs monitoredshallbe:EventparticipationandGrowth rateofPwD supported
Test Mannual
Primary – upto 5,000 per trainee per batch
Advanced – upto 10,000 per trainee per batch
*Stipend for all, including parents/ guardians of PwD
Set up Cost
Trainee Cost
Trainee Stipend
1,00,000/- for both primary and advanced
Primary – 4,200 per trainee per batch
Advanced – 8,000 per trainee per batch
On time on acceptance
of proposal
On completion of
training
On completion of
training
National Level – INR 30,000/-
Regional Level ( participation of
min 5 states) - INR 25,000/-
State Level - INR 20,000/-
District Level - INR
10,000/- 10% of total sales
10,000 per RO per year
50% on approval of event
proposal
50% on completion of event
Annually
Annually
Support for participation
in events
Incentive on Sales
Turnover
Reimbursement for
brochures
21. Sambhav – Aids and Assistive Devices
SchemeDescription
· Additional centres to be set up in cities of India with population of more than 5 million (as per
2011Census)
· Demonstration of aids, assistive devices, software & an accessible model of Kitchen, Living
Room&Bathroometc.forenablingandempowering thePwDs
· ManagementcoordinatorattheseSambhavcentresshallbedeployedby NT
· ROs toprovideonedemonstrator/facilitatorandonemaintenancestaff
· Sambhav centre can procure new aids/ assistive devices and same shall be reimbursed by NT
withinmaximumlimitallowed
· KPIs monitored shall be: increased no. of visitors, organizing visits to the centre (for ROs,
educationalinstituteandMedicalinstitute)
20
Badhte Kadam – Awareness & Community
SchemeDescription
· Awareness generation for general public and community stakeholders through various activities
forexampleexhibition,rallies,workshops, mediaoutreachetc.
· Innovative/specialproposals tobesanctionedseparately
· Create platforms for collaborative initiatives between govt. officials, medical fraternity, legal
professionals&educationalinstitutesfor thebettermentof PwDs
· OutreachactivitiesinareaswhereNTisunderrepresented
· MaximizebenefitsofNTschemes
· KPIs monitored shall be: activities completed, enabling changes in society and gathering
feedback
Test Mannual
Set up Cost Stage I – on approval of application
Stage II – On completion of setup
period
To be paid bi-annually
10,00,000/- (Stage I – 5,00,000
and Stage II – 5,00,000)
40,000/- per month
Monthly Recurring
Cost
Annually
Reimbursement for
new devices
On actuals with maximum limit of
INR 3,20,000/- per annum
Distributing Handouts, posters etc.
at Educational/ financial/ medical
institutes
Sessions with voluntary
organizations like CRY or MAD
Organize Roadshows
20,000/- 17,000/-
15,000/- 16,000/-
13,000/- per
day
8,000/-
Workshops with govt officials,
legal/ medical/ bank/educational
professionals
Social inclusion event like cricket
match
Sessions in schools/ colleges/
other educational institute