This document provides an introduction to the key concepts in life science. It outlines the learning competencies which include explaining the evolving concept of life based on evidence, describing classic experiments on the origin of life, and describing how unifying themes show connections among living things. The topics are divided into the historical development of the concept of life, the origin of the first forms of life, and unifying themes in the study of life. It also discusses the characteristics of life and various theories on how life first originated on Earth.