It talks about Contribution of Antonie Van Leeuwenhoek to the society. It also talks about his life style like a story. It also explains the contribution about microscope and micro organisms.
It talks about Contribution of Antonie Van Leeuwenhoek to the society. It also talks about his life style like a story. It also explains the contribution about microscope and micro organisms.
Microbiology essentially began with the development of the microscope. Although others may have seen microbes before him, it was Antonie van Leeuwenhoek, a Dutch draper whose hobby was lens grinding and making microscopes, who was the first to provide proper documentation of his observations.
A brief introductory overview of microbiology subject matter and what it includes. This presentation and the following was teaching undertaken for Allied Health Sciences BSc as part of my postgraduate degree.
An overview of lactic acid bacteria - IJBInnspub Net
Lactic acid bacteria (LAB) are renowned for the potential of producing antimicrobial compound and other value added products. Undeniable to concern these probiotic has contributed to the importance of human life. Deserving an attention for its capabilities, this paper will discuss on the general description of lactic acid bacteria, genetics, metabolism and its application to the industries. Get the full articles at: http://www.innspub.net/volume-1-number-3-june-2011/
Microbiology essentially began with the development of the microscope. Although others may have seen microbes before him, it was Antonie van Leeuwenhoek, a Dutch draper whose hobby was lens grinding and making microscopes, who was the first to provide proper documentation of his observations.
A brief introductory overview of microbiology subject matter and what it includes. This presentation and the following was teaching undertaken for Allied Health Sciences BSc as part of my postgraduate degree.
An overview of lactic acid bacteria - IJBInnspub Net
Lactic acid bacteria (LAB) are renowned for the potential of producing antimicrobial compound and other value added products. Undeniable to concern these probiotic has contributed to the importance of human life. Deserving an attention for its capabilities, this paper will discuss on the general description of lactic acid bacteria, genetics, metabolism and its application to the industries. Get the full articles at: http://www.innspub.net/volume-1-number-3-june-2011/
Microbiology is the study of organisms that are usually too small to be seen by the unaided eye; it employs techniques—such as sterilization and the use of culture media—that are required to isolate and grow these microorganisms.
Medical Microbiology begins with a review of the immune system, focusing on the body's response to invading microorganisms. Bacteria are then covered, first with a series of chapters presenting the general concepts of bacterial microbiology and then with chapters detailing the major bacterial pathogenes of humans. Similar sections cover virology, mycology, and parasitology. In each section, the introductory chapters stress the mechanisms of infection characteristic of that type of microorganism, thus providing the reader with a framework for understanding rather than memorizing the clinical behavior of the pathogens. The final section of the book Introduction to Infectious Diseases, is arranged by organ system and provides transition for clinical considerations.
Evolution of the Immune System
The immune system consists of factors that provide innate and acquired immunity, and has evolved to become more specific, complex, efficient, and regulated. One of the principal functions of the human immune system is to defend against infecting and other foreign agents by distinguishing self from non-self (foreign antigens) and to marshal other protective responses from leukocytes. The immune system, if dysregulated, can react to self antigens to cause autoimmune diseases or fail to defend against infections.
Organization/Components/Functions
The immune system is organized into discrete compartments to provide the milieu for the development and maintenance of effective immunity. Those two overlapping compartments: the lymphoid and reticuloendothelial systems (RES) house the principal immunologic cells, the leukocytes. Leukocytes derived from pluripotent stem cells in the bone marrow during postnatal life include neutrophils, eosinophils, basophils, monocytes and macrophages, natural killer (NK) cells, and T and B lymphocytes. Hematopoietic and lymphoid precursor cells are derived from pluripotent stem cells. Cells that are specifically committed to each type of leukocyte (colony-forming units) are consequently produced with the assistance of special stimulating factors (e.g. cytokines).
Cells of the immune system intercommunicate by ligand-receptor interactions between cells and/or via secreted molecules called cytokines. Cytokines produced by lymphocytes are termed lymphokines (i.e., interleukins and interferon-γ) and those produced by monocytes and macrophages are termed monokines.
Lymphoid System
Cells of the lymphoid system provide highly specific protection against foreign agents and also orchestrate the functions of other parts of the immune system by producing immunoregulatory cytokines. The lymphoid system is divided into 1) central lymphoid organs, the thymus and bone marrow, and 2) peripheral lymphoid organs, lymph nodes, the spleen, and mucosal and submucosal tissues of the alimentary and respiratory tracts. The thymus instructs certain lymphocytes to differentiate into thymus-dependent (T) lymphocytes and selects most of them to die in...
he culture media are classified in many different ways: Based on the physical state Liquid media Solid media Semisolid media Based on the presence or absence of oxygen Anaerobic media Aerobic media Based on nutritional factors Simple media Synthetic media Complex
Contributions of Various scientist for the development of Microbiology field.
1. Antony Van Leeuwenhoek
2. Edwerd Jenner
3. Louis Pasteur
4. Joseph Lister
5. Robert Koch
6. Paul Ehrlich
7. Alexander Fleming
To understand the basic concepts of the biology of microorganisms and its mechanism of action in host cells.
-Dr SUBASHKUMAR R
Associate Professor in Biotechnology
Sri Ramakrishna College of Arts and Science, Coimbatore
Palestine last event orientationfvgnh .pptxRaedMohamed3
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The people of Punjab felt alienated from main stream due to denial of their just demands during a long democratic struggle since independence. As it happen all over the word, it led to militant struggle with great loss of lives of military, police and civilian personnel. Killing of Indira Gandhi and massacre of innocent Sikhs in Delhi and other India cities was also associated with this movement.
Ethnobotany and Ethnopharmacology:
Ethnobotany in herbal drug evaluation,
Impact of Ethnobotany in traditional medicine,
New development in herbals,
Bio-prospecting tools for drug discovery,
Role of Ethnopharmacology in drug evaluation,
Reverse Pharmacology.
The Roman Empire A Historical Colossus.pdfkaushalkr1407
The Roman Empire, a vast and enduring power, stands as one of history's most remarkable civilizations, leaving an indelible imprint on the world. It emerged from the Roman Republic, transitioning into an imperial powerhouse under the leadership of Augustus Caesar in 27 BCE. This transformation marked the beginning of an era defined by unprecedented territorial expansion, architectural marvels, and profound cultural influence.
The empire's roots lie in the city of Rome, founded, according to legend, by Romulus in 753 BCE. Over centuries, Rome evolved from a small settlement to a formidable republic, characterized by a complex political system with elected officials and checks on power. However, internal strife, class conflicts, and military ambitions paved the way for the end of the Republic. Julius Caesar’s dictatorship and subsequent assassination in 44 BCE created a power vacuum, leading to a civil war. Octavian, later Augustus, emerged victorious, heralding the Roman Empire’s birth.
Under Augustus, the empire experienced the Pax Romana, a 200-year period of relative peace and stability. Augustus reformed the military, established efficient administrative systems, and initiated grand construction projects. The empire's borders expanded, encompassing territories from Britain to Egypt and from Spain to the Euphrates. Roman legions, renowned for their discipline and engineering prowess, secured and maintained these vast territories, building roads, fortifications, and cities that facilitated control and integration.
The Roman Empire’s society was hierarchical, with a rigid class system. At the top were the patricians, wealthy elites who held significant political power. Below them were the plebeians, free citizens with limited political influence, and the vast numbers of slaves who formed the backbone of the economy. The family unit was central, governed by the paterfamilias, the male head who held absolute authority.
Culturally, the Romans were eclectic, absorbing and adapting elements from the civilizations they encountered, particularly the Greeks. Roman art, literature, and philosophy reflected this synthesis, creating a rich cultural tapestry. Latin, the Roman language, became the lingua franca of the Western world, influencing numerous modern languages.
Roman architecture and engineering achievements were monumental. They perfected the arch, vault, and dome, constructing enduring structures like the Colosseum, Pantheon, and aqueducts. These engineering marvels not only showcased Roman ingenuity but also served practical purposes, from public entertainment to water supply.
Instructions for Submissions thorugh G- Classroom.pptxJheel Barad
This presentation provides a briefing on how to upload submissions and documents in Google Classroom. It was prepared as part of an orientation for new Sainik School in-service teacher trainees. As a training officer, my goal is to ensure that you are comfortable and proficient with this essential tool for managing assignments and fostering student engagement.
The Art Pastor's Guide to Sabbath | Steve ThomasonSteve Thomason
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How to Make a Field invisible in Odoo 17Celine George
It is possible to hide or invisible some fields in odoo. Commonly using “invisible” attribute in the field definition to invisible the fields. This slide will show how to make a field invisible in odoo 17.
We all have good and bad thoughts from time to time and situation to situation. We are bombarded daily with spiraling thoughts(both negative and positive) creating all-consuming feel , making us difficult to manage with associated suffering. Good thoughts are like our Mob Signal (Positive thought) amidst noise(negative thought) in the atmosphere. Negative thoughts like noise outweigh positive thoughts. These thoughts often create unwanted confusion, trouble, stress and frustration in our mind as well as chaos in our physical world. Negative thoughts are also known as “distorted thinking”.
Synthetic Fiber Construction in lab .pptxPavel ( NSTU)
Synthetic fiber production is a fascinating and complex field that blends chemistry, engineering, and environmental science. By understanding these aspects, students can gain a comprehensive view of synthetic fiber production, its impact on society and the environment, and the potential for future innovations. Synthetic fibers play a crucial role in modern society, impacting various aspects of daily life, industry, and the environment. ynthetic fibers are integral to modern life, offering a range of benefits from cost-effectiveness and versatility to innovative applications and performance characteristics. While they pose environmental challenges, ongoing research and development aim to create more sustainable and eco-friendly alternatives. Understanding the importance of synthetic fibers helps in appreciating their role in the economy, industry, and daily life, while also emphasizing the need for sustainable practices and innovation.
2. Welcome to Microbiology
For Today…
Introduction to the course.
Explore the history and
foundation of Pharmaceutical
microbiology.
Scope of Microbiology
3. • Microbiology is the study of organisms or agents too
small to be seen with naked eyes.
• The word Microbiology was derived from
Greek: mīkros ("small") + bios ("life")
• Branch of science that is concerned primarily
with the biology of microorganisms and
their effects on other living organisms.
e.g., Bacteria, Protozoa, Algae, Fungus and Viruses.
• When microbiological concepts, processes and
techniques are applied to pharmaceutical operations,
called ‘Pharmaceutical microbiology ’.
Introduction
4. • Microorganisms are present everywhere,
as their presence can be marked in geothermal vents in
the ocean depths to the person’s skin.
• They are also present in soil, air and water.
• Production of 50% of Carbon and 90% of Nitrogen
on earth.
• Biodegradation, digestion and production of
vitamins B12.
• Bread, cheese, beer, vaccines and
antibiotics production.
6. Theory of Spontaneous Generation
• Early belief that some forms of life could arise from
“vital forces” present in nonliving or decomposing
matter, abiogenesis. Or simply, organisms can arise
form non-living matter.
• But this theory was later challenged by many
scientists.
8. • John Needham and Lazzaro Spallanzani were still
supporting theory of spontaneous generation by
proving that air carried germs to the culture media.
• Schwann, Friedrich Schroder and von Dusch (1830s)
disproved them by allowing air to enter flask but only
after passing through a heated tube or sterile wool, so
no growth appeared.
• Still some scientists believed in theory of spontaneous
generation.
9. • In 1665, Robert Hooke (Englishman) reported that
living things were composed of little boxes or cells.
• The first microbes were observed
in 1673
• Antoni van Leeuwenhoek (1673-1723)
(Dutch) described live microorganisms
that he observed in teeth scrapings, rain
water, and peppercorn infusions.
10. Pasteur’s Experiment
• These assumptions provoked Louis Pasteur (1822-
1895) to settle the matter once and for all.
• He first trapped airborne organisms in cotton, then
showed , that piece of cotton caused microbial growth
when placed in sterile medium. Then he did another
experiment to solve the controversy.
• Considered by many as “ Father of Microbiology”
12. • John Tyndall (1820-1893) – dealt a final blow to
spontaneous generation theory in 1877 by
demonstrating that Omission of dust, no growth of
microorganisms.
• He also provided evidence for heat resistant forms of
bacteria.
• A German botanist Ferdinand Cohn (1828-1898)
discovered existence of bacterial endospores.
13. Demonstrations that microorganisms
cause disease
• The first direct demonstration of the role of bacteria
in causing disease came from the study of anthrax by
German Physician Robert Koch (1843-1910).
• His criteria (is still used) to establish the link between a
microorganism and a particular disease that it cause, is
known as Koch's postulates.
14. Koch’s Postulates
• The causative agent must be present in all affected
organisms but absent in healthy individuals.
• The agent must be capable of being isolated
and cultured in pure form.
• When the cultured agent is introduced to a healthy
organism, the same disease must occur.
• The same causative agent must be isolated again
from the affected host.
15. Koch's Postulates
used to
prove the cause
of an infectious
disease.
Sequence of
experimental
steps to relate a
specific microbe
to a specific
disease.
16. The Golden Age of Microbiology
(1857-1914)
• Beginning with Pasteur’s work
• Discoveries included the relationship between
microbes and disease
• Microbes and fermentation
• Immunity
• Anti-microbial drugs
17. • Pasteur showed that microbes are responsible for
fermentation (Germ theory of fermentation).
• Fermentation is the conversation of sugar to alcohol
to make beer and wine.
• Microbial growth is also responsible for
spoilage of food.
• Bacteria that use alcohol and produce acetic acid
spoil wine by turning it to vinegar (acetic acid).
18. Pasteur demonstrated that these
spoilage bacteria could be killed
by heat that was not hot enough to
evaporate the alcohol in wine.
This application of a high heat for
a short time is called
'Pasteurization'.
19. The Germ Theory of Disease
• 1835: Agostino Bassi showed a silkworm
disease was caused by a fungus.
• 1865: Pasteur believed that another silkworm disease
was caused by a protozoan.
• 1840s: Ignaz Semmelwise advocated handwashing
to prevent transmission of puerperal fever from
one OB patient to another.
20. The Germ Theory of Disease….
• 1860s: Joseph Lister used a chemical disinfectant
(Carbolic acid) to prevent surgical wound infections.
• 1876: Robert Koch provided proof that a bacterium
causes anthrax and provided the experimental steps,
• Koch’s postulates, used to prove that a specific
microbe causes a specific disease.
• Koch was a physician and Pasteur’s young rival
21. • A young milkmaid informed the physician Edward
Jenner that she could not get smallpox because she
had already been sick from cowpox.
• 1796: Edward Jenner inoculated a person with
cowpox virus. The person was then protected from
smallpox.
• Called vaccination from vacca for cow
• The protection is called immunity.
22. Chemotherapy – treatment with chemicals
• Chemotherapeutic agents used to treat infectious
disease can be synthetic drugs or antibiotics.
• Antibiotics are chemicals produced by bacteria and
fungi that inhibit or kill other microbes.
• Quinine from tree bark was long used to treat
malaria.
• 1910: Paul Ehrlich developed a synthetic arsenic drug
(magic bullet) salvarsan to treat syphilis.
• 1930s: Sulfonamides were synthesized.
23. • 1928: Alexander Fleming
discovered the first antibiotic.
• He observed that Penicillium
fungus made an antibiotic,
penicillin, that killed S. aureus
(bacteria).
• 1940s: Penicillin was tested
clinically and mass produced.
24. Scope of microbiology ???
• Microbiology has both basic and applied aspects.
• Basic aspects are concerned with biology of
microorganisms includes fields like-
Bacteriology.
Mycology.
Phycology.
Protozoology.
Microbial cytology and physiology.
Microbial genetics.
Molecular biology.
Microbial ecology.
Microbial Taxonomy.
25. Scope of microbiology……
Applied aspects are concerned with practical problems.
These are:
Disease study.
Water and waste water treatment.
Food spoilage and food production.
Industrial uses of microbes.
Medical microbiology,
Immunology,
Industrial microbiology,
Agricultural microbiology
26.
27. Thank you
for
listening
B’coz I believe …
Wash your hand regularly…..
Prevention is Better than Medicine.
Be safe.. be at home.