Forensic scientist manage crime scene evidence for Police Department, Crime Branches, CBI, CID, Forensic Science Laboratories, IB, Banks, Defense/Army, Courts, Quality Control Bureau, Narcotics Dept., Universities, Hospitals, Organizations etc...also in Private Sector like Detective Agencies, Banks, Insurance Companies, Universities, Hospitals, Security Services Agencies, Helpful to Lawyers/Advocates, Law Firms, Private Companies, Own Private Practice etc... they play an integral role in the catching, conviction and acquittal of suspects in cases of all levels .
This presentation is a study material for the forensic aptitude and caliber test (fact and fact plus examination). This contains the topics Principles of forensic science and disciplines of forensic science. For the educational video please go to the link https://youtu.be/VBpgshoOQR4
It is the beginning point for obtaining evidence which will be used by the crime scene investigator and the forensic expert
A thorough investigation of the crime scene must be completed
Crime scene is basically a scene of occurrence of crime. It is a place where a particular crime has been committed.
It is starting point for the investigator.
A complete review of Forensic Science and its various branches.Hamza Mohammad
This is a complete review of Forensic Science and its various branches and the various methodology and techniques used for forensic analysis of various evidences and examination of crime scene.
This presentation is a study material for the forensic aptitude and caliber test (fact and fact plus examination). This contains the topics Principles of forensic science and disciplines of forensic science. For the educational video please go to the link https://youtu.be/VBpgshoOQR4
It is the beginning point for obtaining evidence which will be used by the crime scene investigator and the forensic expert
A thorough investigation of the crime scene must be completed
Crime scene is basically a scene of occurrence of crime. It is a place where a particular crime has been committed.
It is starting point for the investigator.
A complete review of Forensic Science and its various branches.Hamza Mohammad
This is a complete review of Forensic Science and its various branches and the various methodology and techniques used for forensic analysis of various evidences and examination of crime scene.
The are the notes for the newly added subject in B.Sc. Nursing Curriculum in 5th Semester and the subject is Forensic Nursing here is the 1st Unit as per the new 2024 INC Syllabus.
Forensic Science and Technology Advancement .
Introduction of Forensic science.
History of Forensic science.
Milestones in the development of Forensic Techniques.
Artificial intelligence in Forensic Science .
Case Management and Evidence Tracking..
Digital Forensics..
#drxdeepakjatav
DRx Deepak Jatav
Aayushi Namdev
SAM Global University, Raisen Bhopal
Importance of Trace Evidence in Forensic Investigations
Brief Overview of the History of Forensic Science
Richard's entangled aventures in wonderlandRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
Professional air quality monitoring systems provide immediate, on-site data for analysis, compliance, and decision-making.
Monitor common gases, weather parameters, particulates.
Multi-source connectivity as the driver of solar wind variability in the heli...Sérgio Sacani
The ambient solar wind that flls the heliosphere originates from multiple
sources in the solar corona and is highly structured. It is often described
as high-speed, relatively homogeneous, plasma streams from coronal
holes and slow-speed, highly variable, streams whose source regions are
under debate. A key goal of ESA/NASA’s Solar Orbiter mission is to identify
solar wind sources and understand what drives the complexity seen in the
heliosphere. By combining magnetic feld modelling and spectroscopic
techniques with high-resolution observations and measurements, we show
that the solar wind variability detected in situ by Solar Orbiter in March
2022 is driven by spatio-temporal changes in the magnetic connectivity to
multiple sources in the solar atmosphere. The magnetic feld footpoints
connected to the spacecraft moved from the boundaries of a coronal hole
to one active region (12961) and then across to another region (12957). This
is refected in the in situ measurements, which show the transition from fast
to highly Alfvénic then to slow solar wind that is disrupted by the arrival of
a coronal mass ejection. Our results describe solar wind variability at 0.5 au
but are applicable to near-Earth observatories.
(May 29th, 2024) Advancements in Intravital Microscopy- Insights for Preclini...Scintica Instrumentation
Intravital microscopy (IVM) is a powerful tool utilized to study cellular behavior over time and space in vivo. Much of our understanding of cell biology has been accomplished using various in vitro and ex vivo methods; however, these studies do not necessarily reflect the natural dynamics of biological processes. Unlike traditional cell culture or fixed tissue imaging, IVM allows for the ultra-fast high-resolution imaging of cellular processes over time and space and were studied in its natural environment. Real-time visualization of biological processes in the context of an intact organism helps maintain physiological relevance and provide insights into the progression of disease, response to treatments or developmental processes.
In this webinar we give an overview of advanced applications of the IVM system in preclinical research. IVIM technology is a provider of all-in-one intravital microscopy systems and solutions optimized for in vivo imaging of live animal models at sub-micron resolution. The system’s unique features and user-friendly software enables researchers to probe fast dynamic biological processes such as immune cell tracking, cell-cell interaction as well as vascularization and tumor metastasis with exceptional detail. This webinar will also give an overview of IVM being utilized in drug development, offering a view into the intricate interaction between drugs/nanoparticles and tissues in vivo and allows for the evaluation of therapeutic intervention in a variety of tissues and organs. This interdisciplinary collaboration continues to drive the advancements of novel therapeutic strategies.
4. Chemistry
Biology
Physics
Geology
Places physical evidence into a professional
discipline.
to civil and criminal law
}
5.
6. Popularized physical detection
methods in a crime scene
Developed the character Sherlock
Holmes
7. 1887 published first novel, A Study in Scarlet
"I've found it! I've found it," he shouted to my companion, running towards us
with a test-tube in his hand. "I have found a re-agent which is precipitated by
haemoglobin, and by nothing else . . . . Why, man, it is the most practical
medico-legal discovery for years. Don't you see that it gives us an infallible test
for blood stains? . . . . The old guaiacum test was very clumsy and uncertain. So
is the microscopic examination for blood corpuscles. The latter is valueless if the
stains are a few hours old. Now, this appears to act as well whether the blood is
old or new. Had this test been invented, there are hundreds of men now walking
the earth who would long ago have paid the penalty of their crimes. . . . Criminal
cases are continually hinging upon that one point. A man is suspected of a crime
months perhaps after it has been committed. His linen or clothes are examined
and brownish stains discovered upon them. Are they blood stains, or mud stains,
or rust stains, or fruit stains, or what are they? That is a question which has
puzzled many an expert, and why? Because there was no reliable test. Now we
have the Sherlock Holmes's test, and there will no longer be any difficulty."
→ had a considerable influence on popularizing scientific crime-detection methods
8. Father of Forensic Toxicology
1814 - Treatise on detection of poisons
& their effects on animals.
9. Father of Criminal Detection
Devised the first scientific system of
personal identification, using body
measurements known as anthropometry in
1879.
10. Conducted the first definitive study of
fingerprints and their classification.
1892 – Treatise entitled Finger Prints
11. Devised a simple procedure for determining
the blood type (A,B,O,AB) of a dried
bloodstain
12. Used a comparison microscope to
determine if a bullet was fired from a
specific gun
Published study of “tool marks” on bullets
13. Developed fundamental principles of
document examination
1910 – Treatise Questioned Documents
Was responsible for the acceptance of
documents as scientific evidence by the
courts
14. Demonstrated how the principles
developed by Hans Gross could be
incorporated into a workable crime
lab.
Locard's exchange principle states
that once contact is made between
two surfaces a transfer of material(s)
will occur.
15.
16. Since the 1960's the number of crime labs
increased due to the courts demanding
secure scientifically evaluated evidence.
More crime
More drug related crime
Greater need for physical evidence
Use of DNA profiling (1990’s)
18. Physical Science Unit:
Applies the principles and techniques of Chemistry
Physics
Geology
to the identification and comparison of crime-scene
evidence
Biology Unit:
Identifies dried bloodstains and body fluids
Compares hairs and fibers
Identifes and compares botanical materials such as wood
and plants
Performs DNA analysis
19. Firearms Unit: examines
Firearms
Discharged bullets
Cartridge cases
Shotgun shells
Ammunition of all types
Document Examination Unit:
Analyzes handwriting, paper and printers of documents
Photography Unit:
Examines and records physical evidence at the crime
scene and at suspects' locations
20. Toxicology Unit:
Examines body fluids and organs in order to determine
the presence and identification of drugs and poisons
Latent Fingerprint Unit:
Processes and examines evidence for latent fingerprints
i.e. those found on surfaces
Polygraph Unit:
Uses lie detectors, an essential tool of the crime
investigator rather than the forensic scientist
21. Voiceprint Analysis Unit:
Involved in cases of telephone threats or tape-
recorded messages
Investigators may be able to connect a voice to
a particular suspect
Evidence-Collection Unit:
Incorporates evidence collection into a total
forensic science service
22. Analysis of Physical Evidence
The forensic scientist must be skilled in applying the
principles and techniques of the physical and natural
sciences in order to identify the many types of evidence
that may be recovered during crime investigations.
Expert witness
An expert witness possesses a particular skill or has
knowledge in a trade or profession that will aid the
court in determining the truth.
23. Specially trained evidence collection
technicians
□ Training in Proper Recognition,
Collection, and Preservation of
Evidence is required so that
the forensic pathologist, as the
medical examiner or coroner,
can determine the cause of
death via an autopsy.
24. Death can be classified into five
different categories: natural
death, homicide, suicide,
accident or undetermined
manner of death.
Forensic Pathology
The cause of death
can often be
determined by
performing an
autopsy
25. Forensic Pathology – continued
After a human body expires there are several stages of
death
▪ Rigor Mortis
▪ immediately following death, the muscles relax and then
become rigid, shortening of the muscles.
▪ Livor Mortis
▪ when the human heart stops pumping, due to the blood begins
to settle in the parts of the body closest to the ground due to
gravity. The skin will appear dark blue or purple in these lower
areas close to the ground.
▪ Algor Mortis
▪ the process in which the body temperature continually cools
after death until it reaches room temperature, enabling the
medical examiner to establish the general time of death.
26. Forensic Anthropology:
Primarily involves the identification and
examination of skeletal remains, in order to
determine if the remains are human or another
type of animal.
If human, ethnicity, sex, approximate age, and
manner of death can often be determined by an
anthropologist.
27. Forensic Entomology
The study of insects and their developmental
stages
Can help to determine the time of death by
knowing when those stages normally appear in
the insect's life cycle
28. . Forensic Psychiatry
The study of human behavior and legal
proceedings in both civil and criminal cases
In civil and criminal cases, competency often
needs to be determined
In criminal trials, the evaluation of behavior
disorders is often required in order to establish
the psychological profile of a suspect
29. Forensic Odontology
An odontologist can match bite marks to a
suspect's teeth, or match a victim to his dental x-
rays
Results in an identification of an unknown
individual
Forensic Engineering
Used to analyze construction accidents, and the
causes and origins of fires or explosions
30. Can include organic and inorganic
analytical techniques
Organic analysis of unknown substances
▪ Includes analytical techniques such as
Chromatography, UV- visible and infrared
Spectrophotometry and Mass Spectrometry.
Inorganic analysis
▪ Includes techniques such as the emission spectrum of
elements, Atomic Absorption Spectrophotometry,
Neutron Activation Analysis, and X-Ray Diffraction
Analysis.