This document provides an introduction to industrial chemistry. It discusses how industrial chemistry involves developing, optimizing, and monitoring fundamental chemical processes used in industry to transform raw materials into useful commercial products. Industrial chemists study the physical and chemical properties of substances to develop new processes and products. Key aspects of the chemical industry include a focus on profit, competitiveness, reliance on science and technology, large capital requirements, and generally growing through integration rather than diversification. The document contrasts the objectives and approaches of laboratory and industrial chemistry. It also discusses evaluating potential reactions based on factors like thermodynamics, economics, technical feasibility, and environmental issues. Finally, it provides an overview of different skin types (normal, dry, oily, combination,
The document discusses cosmetic dermatology and skin aging. It covers the anatomy of skin, the causes of intrinsic and extrinsic aging, clinical signs of aging and photodamaged skin. It also summarizes treatments for photodamage including chemical peels, fillers, botulinum toxin, lasers and the importance of sun protection and lifestyle factors in skin health.
This document discusses the classification and properties of cosmetics. It summarizes that cosmetics can be classified according to their function, uses, and physical nature. The main functions of cosmetics are decorative, corrective, protective, and curative/therapeutic. Cosmetics are also classified based on whether they are used for the skin, hair, nails, teeth/mouth, or are borderline products. Physically, cosmetics can take the form of aerosols, emulsions, gels, mucilage, oils, cakes, pastes, powders, soaps, solutions, or sticks. The document then discusses the skin and its layers, functions, and common diseases like acne
1) Cosmeceuticals are products that combine characteristics of cosmetics and pharmaceuticals by making claims of drug-like benefits, though they are not regulated as drugs.
2) Many anti-aging cosmeceuticals contain ingredients like vitamins and antioxidants, but these may not be in effective concentrations and formulations to produce results.
3) Marketing of cosmeceuticals often uses tricks and exaggerated claims, suggesting they can do things like penetrate skin to add collagen or use nanotechnology to invisibly fill wrinkles, while the real effects are more limited to temporary moisturizing or minor improvements to skin condition.
Leather industry by ankit nayan(17112012)AnkitNayan4
The document summarizes the key stages in the leather production process, including preparatory stages like soaking, liming, and unhairing; tanning using chromium to convert hide into leather; and crusting where the leather is thinned, retanned, lubricated and sometimes dyed. It notes the high environmental impact of traditional tanning methods due to chemical pollution and waste. Alternative cleaner methods under development include enzyme-assisted and chemical-free processes to reduce this environmental burden.
1. Structure of skin.
2. Skin relating problems :
a. Dry skin
b. Acne
c. Pigmentation
d. Prickly heat
e. Wrinkles
f. Body odour
3. Structure of hair.
4. Hair growth cycle.
The document summarizes the structure and immune functions of normal skin. It describes the two main layers of skin - the epidermis and dermis. The epidermis contains stratified squamous epithelium consisting of multiple layers, while the dermis contains blood vessels, nerves, hair follicles, and sebaceous and sweat glands. It also discusses the roles of Langerhans cells and dermal dendritic cells in cutaneous immunity as antigen presenting cells. The innate immune functions of skin include physical barriers provided by the epidermis, antimicrobial peptides and lipids secreted by keratinocytes, and proinflammatory cytokines like IL-1 and TNF-α that are involved in the acute inflammatory response.
PREPARATION AND CHARACTERIZATION OF THE POLY HERBAL ANTI-AGEING CREAMAvinash More
To prepare and evaluate the polyherbal cosmetic cream comprising extracts of natural products such as aloe, orange peel extract, punica extract and green tea. Extract of aloe (Aloe vera) and Citrus aurintum(orange peel) Green tea (Camelia sinensis) and pomegranate (Punica granatum)are well known for its medicinal value in Indian traditional system of medicine and in ayurvedic preparation. Present work, was based on extraction of these herbs and formulate poly herbal cosmetic cream.
This document presents information about skin and its structure. It discusses how skin is the largest organ, comprising 15% of body weight. It then classifies skin into three layers: the epidermis, dermis, and hypodermis. The epidermis is the outermost layer and ranges in thickness. Below is the dermis, which provides nutritional support and contains sweat glands. The deepest layer is the hypodermis, composed primarily of adipose tissue. In closing, it notes the functions of skin in barrier protection, temperature regulation, and references literature on the topic.
The document discusses cosmetic dermatology and skin aging. It covers the anatomy of skin, the causes of intrinsic and extrinsic aging, clinical signs of aging and photodamaged skin. It also summarizes treatments for photodamage including chemical peels, fillers, botulinum toxin, lasers and the importance of sun protection and lifestyle factors in skin health.
This document discusses the classification and properties of cosmetics. It summarizes that cosmetics can be classified according to their function, uses, and physical nature. The main functions of cosmetics are decorative, corrective, protective, and curative/therapeutic. Cosmetics are also classified based on whether they are used for the skin, hair, nails, teeth/mouth, or are borderline products. Physically, cosmetics can take the form of aerosols, emulsions, gels, mucilage, oils, cakes, pastes, powders, soaps, solutions, or sticks. The document then discusses the skin and its layers, functions, and common diseases like acne
1) Cosmeceuticals are products that combine characteristics of cosmetics and pharmaceuticals by making claims of drug-like benefits, though they are not regulated as drugs.
2) Many anti-aging cosmeceuticals contain ingredients like vitamins and antioxidants, but these may not be in effective concentrations and formulations to produce results.
3) Marketing of cosmeceuticals often uses tricks and exaggerated claims, suggesting they can do things like penetrate skin to add collagen or use nanotechnology to invisibly fill wrinkles, while the real effects are more limited to temporary moisturizing or minor improvements to skin condition.
Leather industry by ankit nayan(17112012)AnkitNayan4
The document summarizes the key stages in the leather production process, including preparatory stages like soaking, liming, and unhairing; tanning using chromium to convert hide into leather; and crusting where the leather is thinned, retanned, lubricated and sometimes dyed. It notes the high environmental impact of traditional tanning methods due to chemical pollution and waste. Alternative cleaner methods under development include enzyme-assisted and chemical-free processes to reduce this environmental burden.
1. Structure of skin.
2. Skin relating problems :
a. Dry skin
b. Acne
c. Pigmentation
d. Prickly heat
e. Wrinkles
f. Body odour
3. Structure of hair.
4. Hair growth cycle.
The document summarizes the structure and immune functions of normal skin. It describes the two main layers of skin - the epidermis and dermis. The epidermis contains stratified squamous epithelium consisting of multiple layers, while the dermis contains blood vessels, nerves, hair follicles, and sebaceous and sweat glands. It also discusses the roles of Langerhans cells and dermal dendritic cells in cutaneous immunity as antigen presenting cells. The innate immune functions of skin include physical barriers provided by the epidermis, antimicrobial peptides and lipids secreted by keratinocytes, and proinflammatory cytokines like IL-1 and TNF-α that are involved in the acute inflammatory response.
PREPARATION AND CHARACTERIZATION OF THE POLY HERBAL ANTI-AGEING CREAMAvinash More
To prepare and evaluate the polyherbal cosmetic cream comprising extracts of natural products such as aloe, orange peel extract, punica extract and green tea. Extract of aloe (Aloe vera) and Citrus aurintum(orange peel) Green tea (Camelia sinensis) and pomegranate (Punica granatum)are well known for its medicinal value in Indian traditional system of medicine and in ayurvedic preparation. Present work, was based on extraction of these herbs and formulate poly herbal cosmetic cream.
This document presents information about skin and its structure. It discusses how skin is the largest organ, comprising 15% of body weight. It then classifies skin into three layers: the epidermis, dermis, and hypodermis. The epidermis is the outermost layer and ranges in thickness. Below is the dermis, which provides nutritional support and contains sweat glands. The deepest layer is the hypodermis, composed primarily of adipose tissue. In closing, it notes the functions of skin in barrier protection, temperature regulation, and references literature on the topic.
Unit XIV discusses environmental chemistry and pollution. It introduces the topics of air, water, and soil pollution and the chemical reactions involved in atmospheric pollution like smog formation, acid rain, and ozone depletion. Major pollutants in the air are discussed like sulfur and nitrogen oxides, hydrocarbons, carbon monoxide and dioxide. The greenhouse effect and global warming due to increased carbon dioxide are also summarized. The document provides definitions of environmental chemistry and pollution and classifies pollution sources and their impacts on the environment.
This document provides an overview of Nuclear Magnetic Resonance Spectroscopy (NMR). NMR is a powerful tool for determining organic structures. It measures the absorption of radiofrequency photons by atomic nuclei with spin in an applied magnetic field. The frequency of absorption depends on the magnetic field strength and chemical environment of the nucleus. Analysis of NMR spectra provides information on a molecule's structure, including the number and type of protons and their connectivity.
This document discusses industrial chemistry and the chemical industry. It defines industrial chemistry as applying chemical processes to natural resources to create products that benefit humanity. It notes that the chemical industry can be divided into commodity chemicals, specialty chemicals, and fine chemicals. Commodity chemicals make up 80% of the market and include basic inorganic and organic chemicals. The chemical industry obtains raw materials from the atmosphere, hydrosphere, lithosphere and biosphere. The document outlines safety considerations for process industries, including process safety management guidelines and elements of a process safety management program.
Sodium hydroxide, also known as lye or caustic soda, is a highly caustic metallic base. It is a white crystalline solid that is odorless, highly soluble in water, and very corrosive. The three main industrial processes for manufacturing sodium hydroxide are the mercury cell process, Nelson diaphragm cell process, and membrane cell process, all of which involve the electrolysis of brine solutions. Sodium hydroxide has a wide variety of industrial uses including in soap making, as a cleaning agent, in aluminum production, and in the paper pulp industry. It can cause severe burns upon contact with skin or tissues due to its highly exothermic and caustic reactions.
Environmental pollution occurs when materials or energy are discharged into the environment in a way that causes harm. It can have both direct and indirect negative impacts on ecosystems. Tropospheric pollution exists in the air in both gaseous and particulate forms from sources like vehicle emissions, industrial pollution, and natural events. Common gaseous pollutants are oxides of sulfur, nitrogen, and carbon which can cause respiratory issues. Particulate matter includes dust, smoke, and liquid droplets. Global warming is caused by the greenhouse effect trapping heat from carbon dioxide and methane in the atmosphere. Acid rain occurs when rainwater falls and reacts with air pollutants like sulfur and nitrogen oxides, lowering its pH and damaging
The document discusses the manufacturing process of cement. It begins with crushing and mixing of raw materials such as limestone, clay, and iron ore. The raw materials are then heated in a kiln to form clinker. Clinker is ground into a fine powder to produce cement. When mixed with water, cement undergoes chemical reactions that result in hardening over time as it hydrates. The hydration process involves calcium silicates and aluminates reacting with water to form compounds like calcium silicate hydrate and calcium aluminate hydrates.
Cement is a binding material made by burning limestone and clay at high temperatures. It is composed mainly of calcium oxides, silica, aluminum, and iron. There are different types of cement used for various purposes based on setting time and chemical resistance. Cement undergoes hydration when mixed with water, resulting in a chemical reaction that causes it to harden. The setting and hardening process allows cement to be used to bind aggregates like sand and gravel into concrete. Cement is tested for consistency, strength development over time, and other characteristics to ensure it meets specifications.
Cement is produced through a process involving mixing and crushing raw materials like limestone and clay, burning the materials in a kiln, and grinding the resulting clinker. The main raw materials are limestone, silica, alumina, and iron oxide. The wet process involves grinding materials into a slurry while the dry process uses powdered materials. The slurry or powder is burned at high temperatures to produce clinker, which is then ground into cement powder. Different types of cement include ordinary Portland cement, sulfate resisting cement, and rapid hardening cement. Cement quality is tested through fineness, setting time, and compressive strength tests.
This document discusses Portland cement and the cement manufacturing process. It begins with an overview of what cement is and how it is used to make concrete. It then describes the industrial process for manufacturing cement, involving grinding raw materials like limestone and clay at high temperatures in a kiln to form clinker, which is then pulverized with gypsum to become Portland cement powder. The document also provides a brief history of cement development and explains how cement kilns can beneficially reuse solid and hazardous wastes as a source of energy and raw material replacement due to the kilns' high temperatures and long retention times.
In this slide Structure of Skin and Hair, Hair Growth Cycle were described followed by skin related diseases such as Acne, dry skin, pigmentation, wrinkles etc.
This document summarizes the biological aspects of cosmetics. It discusses the structure of skin including the epidermis, dermis and hypodermis layers. Common skin problems like dry skin, acne, pigmentation and wrinkles are described along with treatment options. The structure of hair, hair growth cycle involving the anagen, catagen and telogen phases is also outlined. Key functions of skin and hair are protection, regulation and sensory reception. The document provides an overview of basic skin and hair biology relevant to cosmetics.
Formulation, Development and Evaluation of Herbal Antiaging Creamijtsrd
In this study creams were formulated based on the anti aging properties of herbal extracts and its evaluation. Ocimum tenuiflorum used as an active ingredients and extract as a Antibacterial property in these study cream are formulated by oil in water emulsion method. The cream were formulated with Aloeveragel, stearic acid, honey, Glycerin, olive oil, rose oil. The Stability for cream was performed at accelerated condition i.e. 40°C ± 2°C.If can be concluded that herbal creams without side effects having anti bacterial property can be used as provision of a barrier to protect the skin and avoid aging of the skin. Suchita Ghokhale | Dr. Smita T | Roshani Nimgire | Kashi S Ojha | Ujwala Namsale | Anam Mulla "Formulation, Development and Evaluation of Herbal Antiaging Cream" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-6 | Issue-5 , August 2022, URL: https://www.ijtsrd.com/papers/ijtsrd50672.pdf Paper URL: https://www.ijtsrd.com/pharmacy/other/50672/formulation-development-and-evaluation-of-herbal-antiaging-cream/suchita-ghokhale
The document describes the integumentary system and skin anatomy. It discusses the layers of the skin (epidermis, dermis, subcutaneous), glands (sweat and sebaceous), nerves, and functions. The integumentary system protects the body and helps regulate temperature through sweating. Sun exposure is the main factor affecting skin aging, so protection with sunscreen is important.
The document provides an overview of the structure and functions of the integumentary system. It describes the layers of the skin, including the epidermis and dermis. It outlines the principal cells of the epidermis and layers of the epidermis. It also discusses the structure and regions of the dermis, skin pigmentation, accessory structures like hair and glands, and the functions of the skin like protection and thermoregulation. Finally, it covers wound healing, scar formation, and age-related changes to the skin.
The skin is the largest organ of the body and has three main layers - the epidermis, dermis and hypodermis. The epidermis provides the skin's barrier function through its outermost layer, the stratum corneum. The stratum corneum is made up of flattened, anucleate corneocytes surrounded by lipid lamellae of ceramides, cholesterol and fatty acids, which form a protective barrier and prevent water loss. Over 90% of the skin's barrier function resides in the epidermis and stratum corneum. This barrier protects the body by maintaining water levels and preventing microbes and foreign substances from entering.
Semisolids like ointments, creams, gels and pastes are topically applied dosage forms used for therapeutic or cosmetic purposes. They are designed to cling to the skin for prolonged periods. The skin consists of epidermis, dermis and hypodermis layers, and has structures like hair follicles and sweat glands. Drugs can be delivered through the skin via these structures or transcellularly. Factors influencing percutaneous absorption include skin conditions, drug properties, vehicle used, and techniques like penetration enhancers, iontophoresis and sonophoresis. Careful selection of drugs, vehicles and enhancement methods can maximize transdermal drug delivery.
This document provides an overview of the integumentary system, also known as the skin. It discusses the main layers of the skin - the epidermis, dermis and hypodermis - and describes the cells and tissues found in each layer. The epidermis is the outermost layer and contains keratinocytes, melanocytes and other cells. Its five sublayers provide protection and regulate hydration. The dermis below contains collagen, blood vessels and glands. The deepest layer, the hypodermis, comprises fat tissue that insulates the body. Important appendages like hair and nails are also introduced.
Dermatology, Lecture Notes on some Common & Serious Skin & Venereal Diseases.pdfMohammad455814
This document provides an overview of dermatology and common skin diseases. It begins with an introduction to dermatology and the anatomy and physiology of the skin. It then discusses common dermatological lesions and classifications of skin diseases. Specific conditions covered include ichthyosis, naevi, bacterial infections, viral infections, fungal infections, scabies, tuberculosis of the skin, leprosy, seborrheic dermatitis, acne, urticaria, eczema, psoriasis, and various forms of cancerous and precancerous skin lesions. Treatment approaches are also summarized.
Integumentary system
-The organs of the integumentary system include the skin and its accessory structures including hair, nails, and glands, as well as blood vessels, muscles and nerves.
-Dermatology is the medical specialty for the diagnosis and treatment of disorders of the integumentary system.
Structure Of The Skin
The skin (cutaneous membrane) covers the body and is the largest organ of the body by surface area and weight.
Its area is about 2 square meters (22 square feet) and weighs 4.5-5kg (10-11 lb), about 7% of body weight.
It is 0.5 – 4 mm thick, thinnest on the eyelids, thickest on the heels, the average thickness is 1 – 2 mm.
It consists of two major layers:
Outer, thinner layer called the epidermis, consists of epithelial tissue. Inner, thicker layer called the dermis.
Beneath the dermis is a subcutaneous layer (also called hypodermis) which attaches the skin to the underlying tissues and organs.
1. EPIDERMIS
-Covers, protects and waterproofs.
Contains five main layers:
- Stratum Basale
- Stratum Spinosum
- Stratum Granulosum
- Stratum lucidum
- Stratum corneum
The epidermis has a number of important characteristics:
The epidermis is composed of keratinized stratified squamous epithelium.
-It contains four major types of cells:
Keratinocytes (90% of the cells): It produce keratin which is a tough fibrous protein that provides protection.
-Melanocytes: which produce the pigment melanin that protects against damage by ultraviolet radiation.
-Langerhans cells: involved in immune responses, arise from red bone marrow.
-Merkel cells: which function in the sensation of touch along with the adjacent tactile discs.
2. DERMIS
-It is a deeper layer of skin, composed of connective tissue containing collagen and elastic fibers.
-It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands.
-The epidermis is avascular and cells of this layer get their oxygen and nutrients from capillaries in the dermis.
-The dermis can be divided into papillary layer and reticular layer.
Hypodermis :
- The hypodermis (also called the subcutaneous layer) is a layer directly below the dermis and serves to connect the skin to the underlying fascia (fibrous tissue) of the bones and muscles.
--Two types of glands are present in the skin over most of the body
These are sweat glands and sebaceous glands.
--Function Of Skin
Protection:
Sensation:
Heat regulation:
Storage and synthesis:
Synthesis of vitamin D:
Excretion and homeostasis:
Secretion:
Absorption:
Water resistance:
Colour :
Healing of wounds:
Aids in the diagnosis:
Unit XIV discusses environmental chemistry and pollution. It introduces the topics of air, water, and soil pollution and the chemical reactions involved in atmospheric pollution like smog formation, acid rain, and ozone depletion. Major pollutants in the air are discussed like sulfur and nitrogen oxides, hydrocarbons, carbon monoxide and dioxide. The greenhouse effect and global warming due to increased carbon dioxide are also summarized. The document provides definitions of environmental chemistry and pollution and classifies pollution sources and their impacts on the environment.
This document provides an overview of Nuclear Magnetic Resonance Spectroscopy (NMR). NMR is a powerful tool for determining organic structures. It measures the absorption of radiofrequency photons by atomic nuclei with spin in an applied magnetic field. The frequency of absorption depends on the magnetic field strength and chemical environment of the nucleus. Analysis of NMR spectra provides information on a molecule's structure, including the number and type of protons and their connectivity.
This document discusses industrial chemistry and the chemical industry. It defines industrial chemistry as applying chemical processes to natural resources to create products that benefit humanity. It notes that the chemical industry can be divided into commodity chemicals, specialty chemicals, and fine chemicals. Commodity chemicals make up 80% of the market and include basic inorganic and organic chemicals. The chemical industry obtains raw materials from the atmosphere, hydrosphere, lithosphere and biosphere. The document outlines safety considerations for process industries, including process safety management guidelines and elements of a process safety management program.
Sodium hydroxide, also known as lye or caustic soda, is a highly caustic metallic base. It is a white crystalline solid that is odorless, highly soluble in water, and very corrosive. The three main industrial processes for manufacturing sodium hydroxide are the mercury cell process, Nelson diaphragm cell process, and membrane cell process, all of which involve the electrolysis of brine solutions. Sodium hydroxide has a wide variety of industrial uses including in soap making, as a cleaning agent, in aluminum production, and in the paper pulp industry. It can cause severe burns upon contact with skin or tissues due to its highly exothermic and caustic reactions.
Environmental pollution occurs when materials or energy are discharged into the environment in a way that causes harm. It can have both direct and indirect negative impacts on ecosystems. Tropospheric pollution exists in the air in both gaseous and particulate forms from sources like vehicle emissions, industrial pollution, and natural events. Common gaseous pollutants are oxides of sulfur, nitrogen, and carbon which can cause respiratory issues. Particulate matter includes dust, smoke, and liquid droplets. Global warming is caused by the greenhouse effect trapping heat from carbon dioxide and methane in the atmosphere. Acid rain occurs when rainwater falls and reacts with air pollutants like sulfur and nitrogen oxides, lowering its pH and damaging
The document discusses the manufacturing process of cement. It begins with crushing and mixing of raw materials such as limestone, clay, and iron ore. The raw materials are then heated in a kiln to form clinker. Clinker is ground into a fine powder to produce cement. When mixed with water, cement undergoes chemical reactions that result in hardening over time as it hydrates. The hydration process involves calcium silicates and aluminates reacting with water to form compounds like calcium silicate hydrate and calcium aluminate hydrates.
Cement is a binding material made by burning limestone and clay at high temperatures. It is composed mainly of calcium oxides, silica, aluminum, and iron. There are different types of cement used for various purposes based on setting time and chemical resistance. Cement undergoes hydration when mixed with water, resulting in a chemical reaction that causes it to harden. The setting and hardening process allows cement to be used to bind aggregates like sand and gravel into concrete. Cement is tested for consistency, strength development over time, and other characteristics to ensure it meets specifications.
Cement is produced through a process involving mixing and crushing raw materials like limestone and clay, burning the materials in a kiln, and grinding the resulting clinker. The main raw materials are limestone, silica, alumina, and iron oxide. The wet process involves grinding materials into a slurry while the dry process uses powdered materials. The slurry or powder is burned at high temperatures to produce clinker, which is then ground into cement powder. Different types of cement include ordinary Portland cement, sulfate resisting cement, and rapid hardening cement. Cement quality is tested through fineness, setting time, and compressive strength tests.
This document discusses Portland cement and the cement manufacturing process. It begins with an overview of what cement is and how it is used to make concrete. It then describes the industrial process for manufacturing cement, involving grinding raw materials like limestone and clay at high temperatures in a kiln to form clinker, which is then pulverized with gypsum to become Portland cement powder. The document also provides a brief history of cement development and explains how cement kilns can beneficially reuse solid and hazardous wastes as a source of energy and raw material replacement due to the kilns' high temperatures and long retention times.
In this slide Structure of Skin and Hair, Hair Growth Cycle were described followed by skin related diseases such as Acne, dry skin, pigmentation, wrinkles etc.
This document summarizes the biological aspects of cosmetics. It discusses the structure of skin including the epidermis, dermis and hypodermis layers. Common skin problems like dry skin, acne, pigmentation and wrinkles are described along with treatment options. The structure of hair, hair growth cycle involving the anagen, catagen and telogen phases is also outlined. Key functions of skin and hair are protection, regulation and sensory reception. The document provides an overview of basic skin and hair biology relevant to cosmetics.
Formulation, Development and Evaluation of Herbal Antiaging Creamijtsrd
In this study creams were formulated based on the anti aging properties of herbal extracts and its evaluation. Ocimum tenuiflorum used as an active ingredients and extract as a Antibacterial property in these study cream are formulated by oil in water emulsion method. The cream were formulated with Aloeveragel, stearic acid, honey, Glycerin, olive oil, rose oil. The Stability for cream was performed at accelerated condition i.e. 40°C ± 2°C.If can be concluded that herbal creams without side effects having anti bacterial property can be used as provision of a barrier to protect the skin and avoid aging of the skin. Suchita Ghokhale | Dr. Smita T | Roshani Nimgire | Kashi S Ojha | Ujwala Namsale | Anam Mulla "Formulation, Development and Evaluation of Herbal Antiaging Cream" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-6 | Issue-5 , August 2022, URL: https://www.ijtsrd.com/papers/ijtsrd50672.pdf Paper URL: https://www.ijtsrd.com/pharmacy/other/50672/formulation-development-and-evaluation-of-herbal-antiaging-cream/suchita-ghokhale
The document describes the integumentary system and skin anatomy. It discusses the layers of the skin (epidermis, dermis, subcutaneous), glands (sweat and sebaceous), nerves, and functions. The integumentary system protects the body and helps regulate temperature through sweating. Sun exposure is the main factor affecting skin aging, so protection with sunscreen is important.
The document provides an overview of the structure and functions of the integumentary system. It describes the layers of the skin, including the epidermis and dermis. It outlines the principal cells of the epidermis and layers of the epidermis. It also discusses the structure and regions of the dermis, skin pigmentation, accessory structures like hair and glands, and the functions of the skin like protection and thermoregulation. Finally, it covers wound healing, scar formation, and age-related changes to the skin.
The skin is the largest organ of the body and has three main layers - the epidermis, dermis and hypodermis. The epidermis provides the skin's barrier function through its outermost layer, the stratum corneum. The stratum corneum is made up of flattened, anucleate corneocytes surrounded by lipid lamellae of ceramides, cholesterol and fatty acids, which form a protective barrier and prevent water loss. Over 90% of the skin's barrier function resides in the epidermis and stratum corneum. This barrier protects the body by maintaining water levels and preventing microbes and foreign substances from entering.
Semisolids like ointments, creams, gels and pastes are topically applied dosage forms used for therapeutic or cosmetic purposes. They are designed to cling to the skin for prolonged periods. The skin consists of epidermis, dermis and hypodermis layers, and has structures like hair follicles and sweat glands. Drugs can be delivered through the skin via these structures or transcellularly. Factors influencing percutaneous absorption include skin conditions, drug properties, vehicle used, and techniques like penetration enhancers, iontophoresis and sonophoresis. Careful selection of drugs, vehicles and enhancement methods can maximize transdermal drug delivery.
This document provides an overview of the integumentary system, also known as the skin. It discusses the main layers of the skin - the epidermis, dermis and hypodermis - and describes the cells and tissues found in each layer. The epidermis is the outermost layer and contains keratinocytes, melanocytes and other cells. Its five sublayers provide protection and regulate hydration. The dermis below contains collagen, blood vessels and glands. The deepest layer, the hypodermis, comprises fat tissue that insulates the body. Important appendages like hair and nails are also introduced.
Dermatology, Lecture Notes on some Common & Serious Skin & Venereal Diseases.pdfMohammad455814
This document provides an overview of dermatology and common skin diseases. It begins with an introduction to dermatology and the anatomy and physiology of the skin. It then discusses common dermatological lesions and classifications of skin diseases. Specific conditions covered include ichthyosis, naevi, bacterial infections, viral infections, fungal infections, scabies, tuberculosis of the skin, leprosy, seborrheic dermatitis, acne, urticaria, eczema, psoriasis, and various forms of cancerous and precancerous skin lesions. Treatment approaches are also summarized.
Integumentary system
-The organs of the integumentary system include the skin and its accessory structures including hair, nails, and glands, as well as blood vessels, muscles and nerves.
-Dermatology is the medical specialty for the diagnosis and treatment of disorders of the integumentary system.
Structure Of The Skin
The skin (cutaneous membrane) covers the body and is the largest organ of the body by surface area and weight.
Its area is about 2 square meters (22 square feet) and weighs 4.5-5kg (10-11 lb), about 7% of body weight.
It is 0.5 – 4 mm thick, thinnest on the eyelids, thickest on the heels, the average thickness is 1 – 2 mm.
It consists of two major layers:
Outer, thinner layer called the epidermis, consists of epithelial tissue. Inner, thicker layer called the dermis.
Beneath the dermis is a subcutaneous layer (also called hypodermis) which attaches the skin to the underlying tissues and organs.
1. EPIDERMIS
-Covers, protects and waterproofs.
Contains five main layers:
- Stratum Basale
- Stratum Spinosum
- Stratum Granulosum
- Stratum lucidum
- Stratum corneum
The epidermis has a number of important characteristics:
The epidermis is composed of keratinized stratified squamous epithelium.
-It contains four major types of cells:
Keratinocytes (90% of the cells): It produce keratin which is a tough fibrous protein that provides protection.
-Melanocytes: which produce the pigment melanin that protects against damage by ultraviolet radiation.
-Langerhans cells: involved in immune responses, arise from red bone marrow.
-Merkel cells: which function in the sensation of touch along with the adjacent tactile discs.
2. DERMIS
-It is a deeper layer of skin, composed of connective tissue containing collagen and elastic fibers.
-It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands.
-The epidermis is avascular and cells of this layer get their oxygen and nutrients from capillaries in the dermis.
-The dermis can be divided into papillary layer and reticular layer.
Hypodermis :
- The hypodermis (also called the subcutaneous layer) is a layer directly below the dermis and serves to connect the skin to the underlying fascia (fibrous tissue) of the bones and muscles.
--Two types of glands are present in the skin over most of the body
These are sweat glands and sebaceous glands.
--Function Of Skin
Protection:
Sensation:
Heat regulation:
Storage and synthesis:
Synthesis of vitamin D:
Excretion and homeostasis:
Secretion:
Absorption:
Water resistance:
Colour :
Healing of wounds:
Aids in the diagnosis:
The skin has three main layers - the epidermis, dermis and hypodermis. The epidermis is the outermost layer and provides a protective barrier. It has five sublayers including the stratum corneum. The dermis lies beneath the epidermis and contains hair follicles, sweat glands, vessels and nerves. The hypodermis is made of adipose and connective tissue and contains larger blood vessels and nerves. The skin functions to protect the body, regulate temperature, produce vitamin D, detect sensations and store fat.
This document provides an overview of the structure and functions of the skin and its appendages. It notes that the skin is the largest organ and is composed of three main layers - the epidermis, dermis and hypodermis. The epidermis provides protection and waterproofing and has several layers including the stratum basale, stratum spinosum, stratum granulosum and stratum corneum. The dermis lies underneath and contains blood vessels, nerves and connective tissue. The deepest layer, the hypodermis, stores fat and anchors the skin. The document also describes skin appendages like hair, sebaceous glands, sweat glands and nails, and their structure and functions.
This document provides an introduction to solid and semisolid drug preparations. It defines semisolids as products that cling to the skin or mucous membranes for therapeutic, cosmetic, or protective purposes. Semisolids can be applied topically to various areas and exert effects through occlusion and protection. Common semisolid dosage forms include ointments, creams, gels, and pastes. Ointments are oil-based while creams are water-based emulsions. The document outlines factors that influence drug absorption through the skin including skin conditions, physicochemical drug properties, vehicles, and other miscellaneous factors.
The document summarizes key points from Chapter 6 of Hole's Human Anatomy and Physiology textbook regarding the integumentary system. It describes the three main layers of the skin - the epidermis, dermis and subcutaneous layer - and explains the structures and functions of each layer. It also discusses accessory structures of the skin including hair, nails and glands, and how the skin helps regulate body temperature and heals wounds.
Burns are injuries to the skin or other tissues caused by heat, electricity, chemicals, friction or radiation. They are classified by depth and percentage of total body surface area affected. First degree burns only affect the outer layer of skin and cause pain, redness and swelling. Second degree burns are deeper and cause blistering in addition to pain and redness. Third degree burns extend through all layers of skin and can be painless. The risk of infection, fluid loss, and mortality increases with higher percentage of total body surface area burned and deeper burn depth. Proper fluid resuscitation is crucial for large burns to prevent shock from fluid loss.
Science 6_Q2_L2_Parts and Functions of the Integumentary System.pptxkambal1234567890
The integumentary system consists of the skin, hair, nails, and exocrine glands. It functions to protect the body from damage, regulate temperature and water balance, and produce vitamin D. The skin is composed of three layers - the epidermis, dermis, and hypodermis. Hair grows from follicles in the dermis and nails cover the tips of fingers and toes. Sweat and sebaceous glands in the dermis release sweat and oils to regulate temperature and moisture.
The document provides information about the structure and functions of the skin and its role in temperature regulation. It discusses the three main layers of the skin - epidermis, dermis and hypodermis. The epidermis contains keratinocytes, melanocytes and other cell types arranged in multiple layers. The dermis lies below and contains collagen, nerves and blood vessels. Skin appendages like hair follicles, sebaceous and sweat glands are also described. Temperature regulation involves balancing heat production and loss through mechanisms like sweating, vasodilation and shivering controlled by the hypothalamus. Fever is discussed as a regulated increase in set-point temperature in response to infection.
Skin = integument
Skin+ accessory organs = integumentary system.
The integumentary system comprises the skin and its appendages acting to protect the body from various kinds of damage, such as loss of water or damages from outside.
It includes hair, glands and nails.
It has a variety of additional functions; it may serve to waterproof, and protect the deeper tissues, excrete wastes, and regulate body temperature, and is the attachment site for sensory receptors to detect pain, sensation, pressure, and temperature,vitamin D synthesis.
skin and its layuer
Epidermis
Dermis
Hypodermis ( subcutaneous layer)
Epidermis
Most superficial layer of the skin
Approx 10 to 30 cells thick ( epithelial)
Cell types
Keratinocytes -90%
Melanocytes
Merkel cells 10%
Langerhens
stratum basale
Stratum germinativum
Deepest epidermal layer
Attaches to basal lamina
Cells bond to dermis via collagen fibres
Finger like projection called dermal papillae in dermis
Helps in stronger connection
Cells- cuboidal shaped keratinocytes
Grows constantly ,mitosis
Pushed up old cells
Applied aspects
Cells – merkel cell – function as receptor- stimulating sensory nerve fibres
Found in hairless skin.
Abundant on surface of hand and feet.
Melanocytes- produces pigment melanin
- gives hair and skin its color
-protect from u rays
Note: skin color influenced by ,melanin and carotene – carrot, oxygenated haemoglobin
Fingerprints-epidermal ridges
Stratum spinosum
Spiny in appearance
Desmosomsis protruding cell
Interlock between cells
Composed of 8to 10 layers of keratinocytes
Applied aspects
Langerhans cell –as a macrophage by engulfing bacteria and foreign body and damaged cell.
Keratinocytes synthesise keratin and prevent water loss
Stratum granulosam
Has a grainy appearance
Cells become flattened,and cell membrane thicken, and generate large amount of protein keratin and keratohyalin
After cell dies , keratin ,keratohyalin and cell membrane forms stratum lucidum
And accessory structures of hair and nail
Stratum lucidum
Smooth translucent layer
It is found only in thick skin of palms ,soles,digits
Cells are densely packed with eleidin , a clear protein rich in lipids,
Transparent appearance
Stratum corneam
Most superficial layer of epidermis
The increased keratinization of cell
It has 15 to 30 layers of cells
Water is lost from skin in 2 ways
Insensible perspiration
water diffuses from stratum corneum and evaporates from skin
-500 ml per day
Sensible perspiration
Water excreted by sweat glands.
clinical application
Some medications are toxic if swallowed, but safe if used topically (applied to surface of skin)
• Certain topical antibiotics are fairly toxic if taken by mouth, butcan be applied to skin with minimal risk of systemic absorption;they are polar molecules that cannot pass through epidermis toreach blood vessels in dermis; allows for local effect only
• Nonpolar substances cross epidermis much more easily;provides a c
Strategies for Effective Upskilling is a presentation by Chinwendu Peace in a Your Skill Boost Masterclass organisation by the Excellence Foundation for South Sudan on 08th and 09th June 2024 from 1 PM to 3 PM on each day.
Thinking of getting a dog? Be aware that breeds like Pit Bulls, Rottweilers, and German Shepherds can be loyal and dangerous. Proper training and socialization are crucial to preventing aggressive behaviors. Ensure safety by understanding their needs and always supervising interactions. Stay safe, and enjoy your furry friends!
How to Add Chatter in the odoo 17 ERP ModuleCeline George
In Odoo, the chatter is like a chat tool that helps you work together on records. You can leave notes and track things, making it easier to talk with your team and partners. Inside chatter, all communication history, activity, and changes will be displayed.
Executive Directors Chat Leveraging AI for Diversity, Equity, and InclusionTechSoup
Let’s explore the intersection of technology and equity in the final session of our DEI series. Discover how AI tools, like ChatGPT, can be used to support and enhance your nonprofit's DEI initiatives. Participants will gain insights into practical AI applications and get tips for leveraging technology to advance their DEI goals.
Physiology and chemistry of skin and pigmentation, hairs, scalp, lips and nail, Cleansing cream, Lotions, Face powders, Face packs, Lipsticks, Bath products, soaps and baby product,
Preparation and standardization of the following : Tonic, Bleaches, Dentifrices and Mouth washes & Tooth Pastes, Cosmetics for Nails.
This slide is special for master students (MIBS & MIFB) in UUM. Also useful for readers who are interested in the topic of contemporary Islamic banking.
This presentation includes basic of PCOS their pathology and treatment and also Ayurveda correlation of PCOS and Ayurvedic line of treatment mentioned in classics.
Main Java[All of the Base Concepts}.docxadhitya5119
This is part 1 of my Java Learning Journey. This Contains Custom methods, classes, constructors, packages, multithreading , try- catch block, finally block and more.
2. Introduction
What is Industrial Chemistry?
The development, optimization and monitoring
of fundamental chemical processes used in
industry.
It Deals with transforming raw materials and
precursors into useful commercial products for
society
3. Introduction
Industrial Chemists study and apply the
physical and chemical properties of
substances to determine their composition.
They use this information to develop new
substances, processes and products and to
increase scientific knowledge.
4. Characteristics of the Chemical
Industry
1) Basic objective - make a profit
2) Very competitive
3) Highly dependent on science and technology
4) Spends large amounts of its money on R&D
5) Large capital requirements - to construct,
expand and maintain production facilities
6) Low labor requirements - BUT needs highly
qualified personnel
7) Industry Growth - generally through
integration rather than diversification
5. The Chemical Sector at a Glance
Chemicals and chemical products:
• account for ~10% of total world trade in all
commodities
• are the 2nd largest single item of global trade (road
vehicles being the 1st).
World Chemicals Output (2002): $1.6 Trillion USD
• Europe 31% USA 28% Asia/Pacific 27%
Other*14%.
North American Chemicals Output (2002): $505
Billion USD
• USA 92% ($467 Billion
USD)
• Canada 5% ($23 Billion USD)
• Mexico 3% ($15 Billion USD)
6. Laboratory Chemistry vs.
Industrial Chemistry
There are fundamental differences between the design
of a chemical synthesis for industry and that for a
research laboratory.
Students should be able to
1)explain how industrial synthetic approaches differ
from laboratory synthesis methods.
2) evaluate possible reaction schemes based on
thermodynamic, economic, and other
considerations.
7. .g., formation of ethyl alcohol by hydration
of ethylene
Laboratory Scale
• bubble ethylene into 98% H2SO4
• dilute and warm the reaction mixture to hydrolyze
the resultant sulfate ester
8. Laboratory Objectives
• synthesize the product in the most
convenient manner considering:
1) chemist’s time
2) equipment available (usually must use
glassware)
3) conditions achievable
9. Industrial Scale
A stream of ethylene is mixed with steam at
325°C and 1000 psi and passed over a solid
catalyst consisting of phosphoric acid
Unreacted ethylene is recovered and recycled
to the feed stream.
10. Industrial Objectives
• produce the product at minimum total cost
on a scale that will generate the maximum
economic return.
may use:
1) large range of temperatures and pressures
2) batch process or continuous
operation
3) reactants in vapor phase
or liquid phase
11. 1)Evaluation of the reaction
2) Economic feasibility
3) Technical feasibility
4)Other considerations: environmental issues,
Evaluation of a Reaction (process)
12. Evaluation of a Reaction
The chemist must consider not only the well-known,
obvious approaches, but also unknown or untested
approaches. e.g., the manufacture of ethylamine
13. Economic Feasibility
Estimate the difference between the market value
of the products and the reactants.
First approximation, assume:
1) 100% yield
2) no costs of solvents or catalysts
3) no value for co-products
These assumptions must be reassessed further on
in the development stage.
14. There are two basic questions that a chemist or
chemical engineer must ask concerning a given
chemical reaction:
(1) How far does it go, if it is allowed to proceed to
equilibrium? (Does it go in the direction of interest at
all?)
(2) How fast does it progress?
Technical feasibility
16. Unit operation
In transforming matter from inexpensive raw
materials to highly desired products, chemical
engineers became very familiar with the physical
and chemical operations necessary in this
transformation. Examples of this include:
Filtration,
Drying
distillation,
Crystallization
Grinding,
Sedimentation
Combustion,
Catalysis, heat exchange,
Coating, and so on.
18. About the skin
Human skin is a highly complex, highly
important organ, serving many different
functions within the body and being absolutely
essential for human.
Largest organ of the body
There are about 2 m2 of skin covering the
average human body. (2.7 kilograms).
Nearly 15% of total body weight
19. Controls body temperature
Allows us to have the sense of touch through
nerve endings
Skin can become infected with bacteria,
viruses and fungi
Mends itself when damaged
Covers and protects everything inside the
body
About the skin
20. Layers of Skin
The skin is made up of three layers
Epidermis
Dermis
Hypodermis (Subcutaneous fat)
22. What skin looks like
Skin layers may look perfectly smooth
State of the very top layer (epidermis)
Amount of pigment in the layers beneath
State of the tissues
Blood vessels in the deeper skin layers
23. Epidermis
The top layer of the skin, The epidermis is the part of
your skin you can see
The epidermis does not contain any blood vessels
but gets its oxygen and nutrients from the deeper
layers of the skin.
Epidermis is hard at work. At the bottom of the epidermis
new skin cells are forming.
When the cells are ready, they start moving toward the
top of your epidermis. This trip takes about 2 weeks to
a month. As newer cells continue to move up, older cells
near the top die and rise to the surface of your skin.
What you see on your hands are really dead skin cells
24. These old cells are tough and strong, just right for covering
your body and protecting it. But they only stick around for
a little while. Soon, they'll flake off. Though you can't see
it happening, every minute of the day we lose about
30,000 to 40,000 dead skin cells off the surface of our skin.
You've probably lost about 40,000 cells. That's almost
4 kilograms of cells every year! But don't think your
skin might wear out someday. Your epidermis is
always
making new skin cells that rise to the top to replace the
old ones. Most of the cells in your epidermis (95%)
work to make new skin cells
The other 5% tissues make a substance called melanin
25. At the bottom of the epidermis is a very thin membrane
, called the basement membrane.
Function of the basement membrane
1)Attaches the epidermis firmly, though not rigidly, to the
layer below (dermis layer)
2) The second function of the basement membrane is
that of a protective barrier against foreign objects
26. Dermis
The second
layer of the skin
is called Dermis
Dermis contains
blood vessels,
nerves, hair roots
and sweat
glands.
Connective tissue Binds structure of skin
Elastic fibres Makes the skin flexible
Capillaries Tiny blood vessels
Muscle fibres Move the hairs
Sensory cells Touch, pressure, heat,
cold, pain
Nerve fibres Activate muscles and
glands, send messages
to brain
Sweat gland Goes up to the surface
Hair follicles Hair grows through to
the epidermis
Sebaceous gland Produce oil to keep skin
waterproof
27. Dermis
This part of the skin is sandwiched on top of the
Hypodermis (subcutaneous fat) and the epidermis
Dermis is a vitally important area of the skin since it is
here where the fibroblast cells form the network of fibers
of the skin. it is also referred to as the connective tissue.
The connective tissue is mainly made-up of Collagen and
to a far lesser degree Elastin.
C and E are complex proteins responsible for the support
and elasticity of the skin and enables the skin to
regain its shape after being pulled, stretched or pushed.
28. Dermis is fed by blood circulating through tiny arteries,
veins and capillaries to bring nutrition and oxygen to the
Cells whilst removing waste products.
The dermis also contains the sensitive nerve endings,
sweat glands, hair follicles and sebaceous glands (oil
glands
The connective tissue of the dermis is made up of Collagen
and Elastin fibers immersed in glycosaminoglycans.
29. What is collagen?
Collagen is a protein and is found in all body parts,
including the largest organ of the body - the skin.
Collagen accounts for up to 75% of the weight of the
dermis, and is responsible for the resilience and
elasticity of the skin
It is made up of three strands of repeating amino
acids coils coiling into the unique collagen triple helix.
30. The collagen and elastin are responsible for the
strength and elasticity of the skin – and degradation of
the collagen leads to aging and accompanying
wrinkles
Collagen has an amino acid composition, which
differentiates it from other natural proteins.
It contains around 25% glycine, 10% alanine, 12%
proline and 10% hydroxyproline, which is the amino
acids that characterizes collagen
31. What damages collagen ?
1) Sun exposure: free radicals (normal body
functions (oxidation). & Tempreature
2) Inflammation
3) fat filled diet
4)Smoking: kills off ascorbic acid molecule
5)Pollution and toxins in your environment
Vitamin A, Vitamin E , Green Tea , Centella
Hyaluronic Acid , Aldenine®
, Antarcticine®
Serilesine®
32. This is the deepest layer of the skin and is manufactured
by specialist cells.
It is composed mainly of fat (adipose tissue).
The thickness of this layer varies from person to person
and also from one body area to the next.
The hypodermis in women is thicker than in men, which
helps to form the rounded curves in women.
Hypodermis (subcutaneous fat)
33. This layer acts as insulation and protects the internal
organs from temperature variations.
acts as an energy reserve from which the body can draw
as required.
Function of Hypodermis
The sebaceous glands
These glands produce oil, or sebum, which is a mixture
of waxes and fats. The glands empty through minute tubes
called ducts. Sebaceous glands occur in the skin of every
part of the body except on the palms and soles.
35. 1. Normal Skin
In skin that belongs to a normal type, the tissue will not
reveal any traces of oil.
feels neither tight nor greasy
Normal skin should feel vibrant, elastic, and supple.
It looks clean and smooth and has a good circulation and
healthy complexion
with a minimum care, it will look good well into your
advanced age.
Normal skin is the least problematic type.
36. Feels tight and irritable
often looks flaky
often develops fine lines around the eyes
Tightens after washing with soaps or detergents
or prolonged exposure to low humidity
Can easily develop a sallow tone, wrinkles, and fine pores,
and it is very prone to aging and irritating.
It might still great on a young person, but, to keep it health,
you should apply thorough care and use regular skin
natural masks and moisturizers.
2. Dry Skin
37. 3. Oily Skin (seborrhoeic skin)
Oily skin is problematic – it usually looks greasy, thick,
coarse, and shiny, has enlarged pores, and tends to break
into acne.
Oily skin is not prone much to aging and wrinkling
This type of skin is particularly common in adolescents
and young adults.
At this age there is in both sexes a dramatic increase in
sebum production under the influence of sex hormones
The epidermis tends to thicken, due to increased keratin
production, and the pores dilate. As a result the skin
feels rough and irregular.
38. Has patches of both dry and oily skin.
Traces of oil coming from nose and forehead, but will be
clean in the areas that touched cheeks.
Response to many external stimuli by becoming red and
blotchy .
Feel very tight after washing, be prone to developing dry
flaky patches
4. Combination Skin
39. Usually very dry, tends to feel tight, and becomes
inflamed and irritated easily.
5. Sensitive Skin
Develops reddish and scaly areas, can be itchy,
and is prone to breaking into spots.
It is the most problematic and fragile type of skin,
which needs a very special type of care.