This document discusses the importance of biochemistry knowledge for nurses. It notes that biochemistry is relevant from intra-cellular to extra-cellular processes and major diseases. Nurses play an important role in patient care by supporting clinicians, understanding disease conditions, and properly collecting, transporting, and ensuring the reliability of biochemical test samples and results. A sound knowledge of biochemistry pathways and how they can alter in disease is the backbone of biological science and critical for nurses to fulfill their duties and responsibilities in quality patient care.