This study investigated the effects of injection pressure on the performance of a diesel engine using blends of biodiesel produced from Calophyllum oil. Biodiesel was produced through transesterification of the oil with methanol. The biodiesel was blended with diesel at ratios of B10, B20 and B30. Tests were conducted at injection pressures of 120, 150 and 180 bars. Results showed that brake specific fuel consumption decreased with increasing load and was lowest for B20 at 150 bars. Brake thermal efficiency increased with load and was highest for B20 at 150 bars. The optimum injection pressure was determined to be 150 bars when using B20 blend.