This document discusses various ways in which human populations vary and adapt both physically and culturally to different environmental conditions. It covers topics like acclimation, adaptation, albinism, physical variations between populations, Allen's rule, Bergmann's rule, founder effect, genetic drift, impacts of high altitude and agriculture, lactose tolerance, natural selection, responses to heat and cold, skin color variations, vitamin D production, and diseases like smallpox and syphilis. The document is a compilation of definitions and explanations of these biological and anthropological concepts by Obaje Godwin Sunday from the Anatomy Department of Alex Ekwueme Federal University.