This document discusses principles for achieving high availability in Drupal applications. It recommends using version control for all code and configuration, deploying artifacts rather than code directly, and configuring infrastructure and monitoring automation through tools like Chef and Puppet. It also stresses the importance of redundancy across multiple availability zones for critical services and caching, dealing with issues like unique IDs, replication conflicts, and cache flushing across nodes. The document advocates measuring systems thoroughly with logging, metrics and alerts, and contributing optimization work back to the open source community.