Blood coagulation, also known as hemostasis, is the process by which blood changes from a liquid to a solid gel-like substance. It involves three stages: vasoconstriction, formation of a platelet plug, and coagulation of blood. When a blood vessel is injured, a series of reactions are initiated through the intrinsic and extrinsic pathways, ultimately resulting in a cross-linked fibrin mesh that traps blood cells to form a clot. Coagulation is tightly regulated by several mechanisms to prevent excessive clotting. Deficiencies or defects in the coagulation cascade can result in bleeding disorders.