Herpes zoster, also known as shingles, is caused by the reactivation of the varicella zoster virus which causes chickenpox. It results in a painful skin rash with blisters in a limited area, usually on the torso, that is supplied by a single nerve. After a person has chickenpox, the virus remains inactive in the nervous system. Herpes zoster occurs when the virus becomes reactivated, often many years later. Risk factors include older age, immunosuppression, cancer, and HIV infection. The rash usually heals within 2-4 weeks but pain may persist longer.