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Non-Mendelian Genetics
Inheritance Concepts Mendel
Never Imagined!
Non-Mendelian Genetics
 But, not all inheritance is based on the
rules of Complete Dominance!!
Incomplete Inheritance
 The hybrid (heterozygous) offspring
displays a THIRD Phenotype!! Neither trait
is completely dominant, as a result, there
appears to be a blending phenotype.
Red Flower X White Flower = Pink
(RR) (WW) (RW)
Incomplete Inheritance Problem
 What is the probability of pink flowers if
pink flowers are bred with red flowers?
50%
chance
of Pink
Flowers
Incomplete Inheritance Problem
 What is the probability of white flowers if
pink flowers are bred with pink flowers?
CoDominance
 Both traits are dominant, and show up in
the phenotype together. Co means
“together”
 Black Cow X White Cow = Spotted Cow
(BB) (WW) (BW)
CoDominance Problem
 What are all the possible phenotypes
when two spotted cows are bred?
Possible
phenotypes
are a black
cow, 2
spotted
cows, and a
white cow
Blood Type Inheritance Rules:
1. A person with the IA allele
will have A carbohydrates.
2. A person with the IB allele
will have B carbohydrates.
3. A person with the recessive
i allele will have no
carbohydrates.
4. Or a person with both IA and
IB alleles will have both A
and B carbohydrates on
their cells.
Cells Genotypes Blood types
IAi, IAIA Type A
blood
IBi, IBIB Type B
blood
IAIB Type AB
blood
ii Type O
blood
Blood Type Problems
If a woman with AB blood
has children with a man
who has type O, what will
be the possible genotypes
of their children? What will
be their blood types?
IA IB
i
i
IA i
IA i
IB i
IB i
Blood Type Problems
Blood Type Problem 2: A
woman with type B blood
has a child with type O
blood. How is this possible
if her husband has type A
blood?
Multiple Alleles
 When more than 2 varieties exist in a trait.
Many animals have a variety of coat
colors.
Polygenic Traits
Require more than one gene (allele) to
determine trait.
Skin tone is determined by 4-6 genes—that
means that there may be six different
chromosomes involved!
Sex-linked Inheritance
 Genes for some traits are found on the sex
chromosomes (X or y)
 Most of these traits are recessive the normal
gene is dominant
 Heterozygous Females (XXc) are carriers. They
do not show the trait, but carry a gene for the
trait.
 Homozygous Females (XcXc) have the trait
 Males with the gene (XcY) have the trait.—They
do not have another X to counterbalance the
affected gene
Color blindness is a sex-linked
recessive trait. The gene for this trait is
inherited through the X chromosome.
If a woman with normal vision
has children with a man
who is colorblind,
what are the chances
that their children will be
colorblind?
Will any children be carriers
of the trait?
Xc Y
X
X
XXc
XXc
XY
XY
Non-Mendelian Genetics
What are the similarities and differences
between each of these forms of inheritance?
How will you remember? What are
examples of each type?
 Incomplete inheritance
 CoDominance
 Multiple Alleles
 Polygenic Traits
 Sex-linked inheritance

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Heredity: inheritance and variation LESSON IN SCIENCE 9

  • 2. Non-Mendelian Genetics  But, not all inheritance is based on the rules of Complete Dominance!!
  • 3. Incomplete Inheritance  The hybrid (heterozygous) offspring displays a THIRD Phenotype!! Neither trait is completely dominant, as a result, there appears to be a blending phenotype. Red Flower X White Flower = Pink (RR) (WW) (RW)
  • 4. Incomplete Inheritance Problem  What is the probability of pink flowers if pink flowers are bred with red flowers? 50% chance of Pink Flowers
  • 5. Incomplete Inheritance Problem  What is the probability of white flowers if pink flowers are bred with pink flowers?
  • 6. CoDominance  Both traits are dominant, and show up in the phenotype together. Co means “together”  Black Cow X White Cow = Spotted Cow (BB) (WW) (BW)
  • 7. CoDominance Problem  What are all the possible phenotypes when two spotted cows are bred? Possible phenotypes are a black cow, 2 spotted cows, and a white cow
  • 8. Blood Type Inheritance Rules: 1. A person with the IA allele will have A carbohydrates. 2. A person with the IB allele will have B carbohydrates. 3. A person with the recessive i allele will have no carbohydrates. 4. Or a person with both IA and IB alleles will have both A and B carbohydrates on their cells. Cells Genotypes Blood types IAi, IAIA Type A blood IBi, IBIB Type B blood IAIB Type AB blood ii Type O blood
  • 9. Blood Type Problems If a woman with AB blood has children with a man who has type O, what will be the possible genotypes of their children? What will be their blood types? IA IB i i IA i IA i IB i IB i
  • 10. Blood Type Problems Blood Type Problem 2: A woman with type B blood has a child with type O blood. How is this possible if her husband has type A blood?
  • 11. Multiple Alleles  When more than 2 varieties exist in a trait. Many animals have a variety of coat colors.
  • 12. Polygenic Traits Require more than one gene (allele) to determine trait. Skin tone is determined by 4-6 genes—that means that there may be six different chromosomes involved!
  • 13. Sex-linked Inheritance  Genes for some traits are found on the sex chromosomes (X or y)  Most of these traits are recessive the normal gene is dominant  Heterozygous Females (XXc) are carriers. They do not show the trait, but carry a gene for the trait.  Homozygous Females (XcXc) have the trait  Males with the gene (XcY) have the trait.—They do not have another X to counterbalance the affected gene
  • 14. Color blindness is a sex-linked recessive trait. The gene for this trait is inherited through the X chromosome. If a woman with normal vision has children with a man who is colorblind, what are the chances that their children will be colorblind? Will any children be carriers of the trait? Xc Y X X XXc XXc XY XY
  • 15. Non-Mendelian Genetics What are the similarities and differences between each of these forms of inheritance? How will you remember? What are examples of each type?  Incomplete inheritance  CoDominance  Multiple Alleles  Polygenic Traits  Sex-linked inheritance