This document provides an overview of hepatitis B, including its prevalence, screening, diagnosis, and management. Some key points are: - Hepatitis B affects an estimated 350 million people globally and 0.8-1.4 million in the US. Vaccination programs have reduced new infections in the US. - Screening involves testing for hepatitis B surface antigen and other serologic markers. - Acute hepatitis B resolves in 95% of cases, while 5% develop chronic infection. Treatment aims to reduce liver inflammation and prevent cirrhosis or cancer. - Approved treatments include pegylated interferon and oral antiviral agents like entecavir. Monitoring includes liver enzymes and HBV DNA levels. Comp