Petroleum is formed from organic materials that are deposited in sedimentary basins over millions of years. The key steps in petroleum formation include: (1) deposition and burial of organic-rich source rocks; (2) generation of hydrocarbons from the buried organic matter through thermal maturation; (3) migration of hydrocarbons from the source rock into reservoir rocks; and (4) accumulation of hydrocarbons in structural or stratigraphic traps in reservoir rocks where they are preserved. Successful petroleum exploration requires identification of source, reservoir, and seal rocks in areas with suitable burial and thermal histories to generate and trap commercial quantities of oil and gas.
This presentation is all about Petroleum Engineering, Prospecting oil and gas, drilling and various drilling methods, logs and its types, different Drive Mechanisms, etc......
The process of transportation of petroleum from its place of origin, the source rock, to its place of accumulation into the reservoir up to the trap is termed as Migration.
This presentation is all about Petroleum Engineering, Prospecting oil and gas, drilling and various drilling methods, logs and its types, different Drive Mechanisms, etc......
The process of transportation of petroleum from its place of origin, the source rock, to its place of accumulation into the reservoir up to the trap is termed as Migration.
Contains a short description of source rock and it is classified whilst making due diligence to relate it to its importance to geologist (or economic importance in general)
This document provides a basic overview of the fundamental rock properties. It delivers a detailed analysis of the basic reservoir rock properties like porosity, permeability, Fluid saturation , wettability, etc.
Contains a short description of source rock and it is classified whilst making due diligence to relate it to its importance to geologist (or economic importance in general)
This document provides a basic overview of the fundamental rock properties. It delivers a detailed analysis of the basic reservoir rock properties like porosity, permeability, Fluid saturation , wettability, etc.
Oil shale resource is called unconventional oil resources to distinguish them from oil which can be extracted using traditional oil well methods (e.g., conventional oil resources). Most of the world's oil reserves are recorded as unconventional crude oil. Oil shale deposits represent staggering resource figures. Estimates by the U.S. Geological Survey suggest a global resource of 3 trillion (1012) barrels of oil, but reasonable estimates as high as 12 trillion barrels have been made. About half of the resource is located in the western United States. This articles aims to sight some light on the oil shale as the important types of unconventional oil deposits in the earth as well as how much can be economically recovered from oil shale.
Petroleum Principles: definitions, chemistry, how oil & gas formed throughout history, formation, accumulation, traps, reservoir types, petroleum industry, Total E & P in two words
Seminar of U.V. Spectroscopy by SAMIR PANDASAMIR PANDA
Spectroscopy is a branch of science dealing the study of interaction of electromagnetic radiation with matter.
Ultraviolet-visible spectroscopy refers to absorption spectroscopy or reflect spectroscopy in the UV-VIS spectral region.
Ultraviolet-visible spectroscopy is an analytical method that can measure the amount of light received by the analyte.
Richard's entangled aventures in wonderlandRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Introduction:
RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is an important biological process for modulating eukaryotic gene expression.
It is highly conserved process of posttranscriptional gene silencing by which double stranded RNA (dsRNA) causes sequence-specific degradation of mRNA sequences.
dsRNA-induced gene silencing (RNAi) is reported in a wide range of eukaryotes ranging from worms, insects, mammals and plants.
This process mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes.
What are small ncRNAs?
micro RNA (miRNA)
short interfering RNA (siRNA)
Properties of small non-coding RNA:
Involved in silencing mRNA transcripts.
Called “small” because they are usually only about 21-24 nucleotides long.
Synthesized by first cutting up longer precursor sequences (like the 61nt one that Lee discovered).
Silence an mRNA by base pairing with some sequence on the mRNA.
Discovery of siRNA?
The first small RNA:
In 1993 Rosalind Lee (Victor Ambros lab) was studying a non- coding gene in C. elegans, lin-4, that was involved in silencing of another gene, lin-14, at the appropriate time in the
development of the worm C. elegans.
Two small transcripts of lin-4 (22nt and 61nt) were found to be complementary to a sequence in the 3' UTR of lin-14.
Because lin-4 encoded no protein, she deduced that it must be these transcripts that are causing the silencing by RNA-RNA interactions.
Types of RNAi ( non coding RNA)
MiRNA
Length (23-25 nt)
Trans acting
Binds with target MRNA in mismatch
Translation inhibition
Si RNA
Length 21 nt.
Cis acting
Bind with target Mrna in perfect complementary sequence
Piwi-RNA
Length ; 25 to 36 nt.
Expressed in Germ Cells
Regulates trnasposomes activity
MECHANISM OF RNAI:
First the double-stranded RNA teams up with a protein complex named Dicer, which cuts the long RNA into short pieces.
Then another protein complex called RISC (RNA-induced silencing complex) discards one of the two RNA strands.
The RISC-docked, single-stranded RNA then pairs with the homologous mRNA and destroys it.
THE RISC COMPLEX:
RISC is large(>500kD) RNA multi- protein Binding complex which triggers MRNA degradation in response to MRNA
Unwinding of double stranded Si RNA by ATP independent Helicase
Active component of RISC is Ago proteins( ENDONUCLEASE) which cleave target MRNA.
DICER: endonuclease (RNase Family III)
Argonaute: Central Component of the RNA-Induced Silencing Complex (RISC)
One strand of the dsRNA produced by Dicer is retained in the RISC complex in association with Argonaute
ARGONAUTE PROTEIN :
1.PAZ(PIWI/Argonaute/ Zwille)- Recognition of target MRNA
2.PIWI (p-element induced wimpy Testis)- breaks Phosphodiester bond of mRNA.)RNAse H activity.
MiRNA:
The Double-stranded RNAs are naturally produced in eukaryotic cells during development, and they have a key role in regulating gene expression .
The increased availability of biomedical data, particularly in the public domain, offers the opportunity to better understand human health and to develop effective therapeutics for a wide range of unmet medical needs. However, data scientists remain stymied by the fact that data remain hard to find and to productively reuse because data and their metadata i) are wholly inaccessible, ii) are in non-standard or incompatible representations, iii) do not conform to community standards, and iv) have unclear or highly restricted terms and conditions that preclude legitimate reuse. These limitations require a rethink on data can be made machine and AI-ready - the key motivation behind the FAIR Guiding Principles. Concurrently, while recent efforts have explored the use of deep learning to fuse disparate data into predictive models for a wide range of biomedical applications, these models often fail even when the correct answer is already known, and fail to explain individual predictions in terms that data scientists can appreciate. These limitations suggest that new methods to produce practical artificial intelligence are still needed.
In this talk, I will discuss our work in (1) building an integrative knowledge infrastructure to prepare FAIR and "AI-ready" data and services along with (2) neurosymbolic AI methods to improve the quality of predictions and to generate plausible explanations. Attention is given to standards, platforms, and methods to wrangle knowledge into simple, but effective semantic and latent representations, and to make these available into standards-compliant and discoverable interfaces that can be used in model building, validation, and explanation. Our work, and those of others in the field, creates a baseline for building trustworthy and easy to deploy AI models in biomedicine.
Bio
Dr. Michel Dumontier is the Distinguished Professor of Data Science at Maastricht University, founder and executive director of the Institute of Data Science, and co-founder of the FAIR (Findable, Accessible, Interoperable and Reusable) data principles. His research explores socio-technological approaches for responsible discovery science, which includes collaborative multi-modal knowledge graphs, privacy-preserving distributed data mining, and AI methods for drug discovery and personalized medicine. His work is supported through the Dutch National Research Agenda, the Netherlands Organisation for Scientific Research, Horizon Europe, the European Open Science Cloud, the US National Institutes of Health, and a Marie-Curie Innovative Training Network. He is the editor-in-chief for the journal Data Science and is internationally recognized for his contributions in bioinformatics, biomedical informatics, and semantic technologies including ontologies and linked data.
(May 29th, 2024) Advancements in Intravital Microscopy- Insights for Preclini...Scintica Instrumentation
Intravital microscopy (IVM) is a powerful tool utilized to study cellular behavior over time and space in vivo. Much of our understanding of cell biology has been accomplished using various in vitro and ex vivo methods; however, these studies do not necessarily reflect the natural dynamics of biological processes. Unlike traditional cell culture or fixed tissue imaging, IVM allows for the ultra-fast high-resolution imaging of cellular processes over time and space and were studied in its natural environment. Real-time visualization of biological processes in the context of an intact organism helps maintain physiological relevance and provide insights into the progression of disease, response to treatments or developmental processes.
In this webinar we give an overview of advanced applications of the IVM system in preclinical research. IVIM technology is a provider of all-in-one intravital microscopy systems and solutions optimized for in vivo imaging of live animal models at sub-micron resolution. The system’s unique features and user-friendly software enables researchers to probe fast dynamic biological processes such as immune cell tracking, cell-cell interaction as well as vascularization and tumor metastasis with exceptional detail. This webinar will also give an overview of IVM being utilized in drug development, offering a view into the intricate interaction between drugs/nanoparticles and tissues in vivo and allows for the evaluation of therapeutic intervention in a variety of tissues and organs. This interdisciplinary collaboration continues to drive the advancements of novel therapeutic strategies.
Observation of Io’s Resurfacing via Plume Deposition Using Ground-based Adapt...Sérgio Sacani
Since volcanic activity was first discovered on Io from Voyager images in 1979, changes
on Io’s surface have been monitored from both spacecraft and ground-based telescopes.
Here, we present the highest spatial resolution images of Io ever obtained from a groundbased telescope. These images, acquired by the SHARK-VIS instrument on the Large
Binocular Telescope, show evidence of a major resurfacing event on Io’s trailing hemisphere. When compared to the most recent spacecraft images, the SHARK-VIS images
show that a plume deposit from a powerful eruption at Pillan Patera has covered part
of the long-lived Pele plume deposit. Although this type of resurfacing event may be common on Io, few have been detected due to the rarity of spacecraft visits and the previously low spatial resolution available from Earth-based telescopes. The SHARK-VIS instrument ushers in a new era of high resolution imaging of Io’s surface using adaptive
optics at visible wavelengths.
3. What is Petroleum?
• A naturally occurring flammable liquid that is found in geologic formation below
Earth’s surface and consists of a mixture of hydrocarbons and/or non
hydrocarbons. (Petroleum deposits are epigenetic).
Solid hydrocarbons : Asphalt
Liquid hydrocarbons : Crude oil
Gas hydrocarbons : Methane, Butane, Propane etc.
3
Introduction
4. 4
Formation of Petroleum
Two basic parameters of the Process of Petroleum Formation
• Elements
• Processes
Elements
Source rock
Reservoir rock
TOC value
Seal rock(Trap)
Processes
Generation
Migration
Accumulation
Preservation
Figure 02 : Formation of petroleum
5. 5
Source rock
Naturally occurring fine-grained sediments that has generated and released enough
hydrocarbons to form commercial accumulation of oil and/or gas.
Organic matter in source rock is determined by,
• The amount of light
• Water depth
• Latitude
• Water temperature
• Water turbidity
• The abundance of nutrient preferred by plants
(Ex: phosphates and nitrates)
Source Rock
Effective Possible Potential
Already generated and
expelled hydrocarbons
Source potential has
not yet been evaluated
Immature type, need more
thermal maturity to generate
and expel hydrocarbons
6. 6
Reservoir Rock
• Oil and gas are accumulated in reservoir rocks.
• A reservoir rock must be;
Permeable
Porous
• Common reservoir rocks are sandstones and carbonates.
Figure 03: Reservoir rock
7. 7
TOC and Rock Eval - Pyrolysis
• TOC (Total Organic Carbon): a measurement of the organic richness of
sedimentary rocks
• S1 : the amount of free hydrocarbon
• S2 : the amount of the remaining hydrocarbon potential
• S3 : the amount of carbon dioxide released during pyrolysis
• Hydrogen Index (HI) : the hydrogen richness = (S2/TOC)×100%
• Oxygen Index (OI) : the oxygen richness = (S3/TOC)×100%
8. 8
Rock Eval - Pyrolysis
• It is used to identify the type and maturity of organic matter and to detect
petroleum potential in sediments.
• Tmax
represents the temperature at which the maximum amount of
hydrocarbons degraded from kerogen are generated
• The Production Index (PI)
is also in part indicative of the degree of thermal maturity
PI = S1/(S1+S2)
PI < 0.4 = immature
PI : between 0.4 and 1.0 = mature
PI > 1.0 are indicative of over mature
9. 9
Seal (Trap) Rock
An impermeable rock that act as a barrier to further migration of hydrocarbon liquids.
• Shale, Mudstone
• Anhydrite
• Salt
Traps can be described as,
• Stratigraphic traps (Due to depositional characteristics)
• Structural traps ( Due to Tectonic Events – Anticlines, Fault traps, Salt domes)
• Combined traps (Both Structural and Stratigraphic)
Figure 04: Common types of hydrocarbon traps
10. 10
Generation
• Maturity
• Age of source rock
• Maximum temperature, Vitrinite Reflectance Value and Biomarkers
R𝑜 > 0.55 - Mature – can produce oil
R𝑜 < 0.55 – Immature – can not produce oil
• Fine-grained sediments
• Total Organic Carbon > 1wt%
Figure 05: Three
stages undergone by
organic matter rich
sediments
11. 11
Table 01: Types of Kerogen associated with the formation of Petroleum
12. 12
Migration
• Two types,
Primary migration :
Generated oil migrate within the source rock
Secondary migration :
Generated oil migrate beyond the source rock
Accumulation
• For accumulation there should be:
Source rocks
Migration
Reservoir rock
Trap
Figure 06: Migration and
Accumulation of Petroleum
13. 13
Oil and Gas
generation windows
• Oil window : Temperature range in which
oil forms relative to depth
• Gas window : Temperature range in
which gas forms relative to
depth
Figure 07: Generation of Petroleum
with geothermal gradient.
14. 14
Preservation potential
Most important conditions
• Anaerobic conditions(Low oxygen content)
• Rapid sedimentation by fine-grained material
Figure 08: Oxic and
anoxic conditions of
depositional
environments
15. 15
Age of Formation and Timing
Found to be formed about ~113 Ma in the Albian-Aptian age of the lower Cretaceous
period belonging to Mesozoic era in the Phanerozoic eonothem.
The amount of time it takes to create petroleum is not precisely known.
This is a slow process which takes millions of years (~20 million years).
17. 17
• Chemistry
Geochemistry is a major component of petroleum geology
• Detailed knowledge of mineralogical composition of rocks –
reservoir quality.
• Pore-fluid chemistry.
• Physics
Geophysics contributes to:
• Understand the structures involved in trapping : folds , faults
• Understanding the wells : wireline logs, lithology, porosity
• Biology
• Biochemistry : transformation of plant and animal tissues into
kerogen and through to oil and gas.
• Study of fossils life : paleontology
18. 18
OPEC – Organization of Petroleum Exporting
Countries
• Major organization out of OPEC, OEDC and Countries in former Soviet Union.
• Group of 13 countries
• Saudi Arabia, Kuwait, Mexico, Iraq, Iran, Alaska, Texas, Venezuela,
Some leading petroleum companies in the world
• Sinopec-China Petroleum
• China National Petroleum
• Royal Dutch Shell
• Exxon Mobil
• British Petroleum
• Total
• Chevron
• Gazprom
• Petrobras
• Lukoil
Figure 09: Petroleum exporting countries
19. 19
• The petroleum geology lies within
a continuum of disciplines,
beginning with geophysics and
ending with petroleum
engineering, but overlapping both
in time and subject matter.
• The flowchart showing how
petroleum geology is only one
aspect of petroleum exploration
and production, and how these
enterprises themselves are part of
a continuum of events.
20. 20
• Transportation
Ex: Petrol, Diesel
• Industrial Powers
Ex: Diesel, Gasoline
• Heating and Lighting
Ex: Kerosene
• Lubricants
• Petro chemical industry
Ex: Chemical fertilizers, Synthetic fiber, Synthetic rubber, Nylon,
Plastics, Pesticides and insecticides, Perfumes, Dyes, Paints,
Carbon black and Sulphur, etc.
• Use of by-products
Ex: Petrol, Paraffin, Diesel, Gas oil, Plastic, Detergents, Aviation
gasoline, Naphtha, Vaseline, Wax, Butadiene, Asphalt
Figure 10 : Uses of Petroleum
Uses of Petroleum