Gangrene occurs when tissues die due to lack of blood flow and oxygen. There are three main types: dry gangrene caused by lack of oxygen, wet gangrene caused by bacterial infection which is more dangerous, and gas gangrene caused by Clostridia bacteria. Symptoms include pain, swelling, discoloration and odor. Treatments depend on the type but may include antibiotics, surgery to improve blood flow, hyperbaric oxygen therapy, debriding dead tissue, and amputation of severely affected body parts.