The document discusses the integrative functions of the diencephalon and subcortical ganglia. It describes the nuclei and functions of the thalamus and hypothalamus. The thalamus is divided into specific relay nuclei, motor nuclei, and associative nuclei that integrate sensory information and regulate movements and behaviors. The hypothalamus receives internal and external signals to regulate homeostasis, emotions, and motivations through connections with the limbic system, somatic and vegetative nervous systems, and endocrine system. The basal ganglia, consisting of the striatum and globus pallidus, integrate motor and associative cortical functions and facilitate complex movements through connections with the motor thalamus and brainstem. Dys
The document summarizes key information about the structure and function of the human cerebral cortex. It discusses the layers of the cortex, methods used to study cortical functions including stimulation and electrophysiological procedures like EEG. Specific topics covered include sensory and motor areas of the cortex, sleep centers and stages of sleep, and the influence of the reticular formation on cortical activity.
This document discusses the physiology of higher nervous activity. It describes behavior as interactions with the external environment accompanied by vegetative reactions. Higher nervous activity involves human adjustment to changing external conditions and involves cortical and sub-cortical structures. Behavior can be inborn, involving unconditioned reflexes, or acquired through conditioned reflexes. Conditioned reflexes are individually acquired and adjusted to changing external environments. The document also examines the formation of conditioned reflexes and different types of inhibition.
Hind Brain in regulation of Motor functionsEneutron
1. The hind brain regulates motor functions through reflexes mediated by the medulla oblongata and midbrain.
2. The medulla oblongata contains structures that mediate vital reflexes like respiration as well as protective reflexes like coughing and sneezing.
3. The midbrain contains structures that produce tonic and orientation reflexes regulating posture and equilibrium.
This document discusses speech physiology and the centers involved in speech production and comprehension. It covers topics like:
- The dominant and non-dominant hemispheres and their roles
- Brain areas involved in speech like Wernicke's area, Broca's area, and their functions
- Types of aphasia that can result from lesions to different speech areas
- The mechanism of speech production and comprehension involving various brain areas
- Other topics on neglect, dysarthria, and the lateralization of brain functions are also summarized.
A reflex arc is a neural pathway that controls a reflex response. It consists of a receptor that detects a stimulus, a sensory neuron that conveys this information to the spinal cord, an interneuron that relays the signal to a motor neuron, which then activates an effector such as a muscle or gland. This allows reflex actions to occur quickly through the spinal cord without involving the brain. Common spinal reflexes include the stretch reflex, Golgi tendon reflex, crossed extensor reflex, and withdrawal reflex.
The document discusses the types of nervous systems classified by Pavlov and their characteristics. Pavlov classified nervous systems according to their levels of excitation and inhibition. The four main types are: 1) strong unbalanced with predominance of excitation, 2) strong well-balanced active with high mobility, 3) strong well-balanced passive with low mobility, and 4) weak with extremely weak excitation and inhibition leading to fatigue. Different nervous system types determine the rate of forming new conditioned reflexes and their strength and stability.
This document outlines a plan for a presentation on inhibition in the central nervous system. It will define inhibition, describe the roles of inhibition in protection and coordination. It will explain excitatory and inhibitory postsynaptic potentials and the major inhibitory neurotransmitters like GABA. It will classify inhibition by location, mechanism, and nature. It will cover topics like lateral, reciprocal, and Renshaw inhibition. It will also discuss Sechenov's pioneering experiment demonstrating central inhibition in the brain. References will be included.
The document discusses the autonomic nervous system (ANS), which controls internal organs and glands. It describes the ANS as having two divisions - the sympathetic and parasympathetic systems. The sympathetic system activates the body's fight or flight response through secretion of epinephrine and norepinephrine from the adrenal medulla. The parasympathetic system acts to slow functions down and return the body to homeostasis. The document provides details on the pathways, targets, and functions of both divisions of the ANS.
The document summarizes key information about the structure and function of the human cerebral cortex. It discusses the layers of the cortex, methods used to study cortical functions including stimulation and electrophysiological procedures like EEG. Specific topics covered include sensory and motor areas of the cortex, sleep centers and stages of sleep, and the influence of the reticular formation on cortical activity.
This document discusses the physiology of higher nervous activity. It describes behavior as interactions with the external environment accompanied by vegetative reactions. Higher nervous activity involves human adjustment to changing external conditions and involves cortical and sub-cortical structures. Behavior can be inborn, involving unconditioned reflexes, or acquired through conditioned reflexes. Conditioned reflexes are individually acquired and adjusted to changing external environments. The document also examines the formation of conditioned reflexes and different types of inhibition.
Hind Brain in regulation of Motor functionsEneutron
1. The hind brain regulates motor functions through reflexes mediated by the medulla oblongata and midbrain.
2. The medulla oblongata contains structures that mediate vital reflexes like respiration as well as protective reflexes like coughing and sneezing.
3. The midbrain contains structures that produce tonic and orientation reflexes regulating posture and equilibrium.
This document discusses speech physiology and the centers involved in speech production and comprehension. It covers topics like:
- The dominant and non-dominant hemispheres and their roles
- Brain areas involved in speech like Wernicke's area, Broca's area, and their functions
- Types of aphasia that can result from lesions to different speech areas
- The mechanism of speech production and comprehension involving various brain areas
- Other topics on neglect, dysarthria, and the lateralization of brain functions are also summarized.
A reflex arc is a neural pathway that controls a reflex response. It consists of a receptor that detects a stimulus, a sensory neuron that conveys this information to the spinal cord, an interneuron that relays the signal to a motor neuron, which then activates an effector such as a muscle or gland. This allows reflex actions to occur quickly through the spinal cord without involving the brain. Common spinal reflexes include the stretch reflex, Golgi tendon reflex, crossed extensor reflex, and withdrawal reflex.
The document discusses the types of nervous systems classified by Pavlov and their characteristics. Pavlov classified nervous systems according to their levels of excitation and inhibition. The four main types are: 1) strong unbalanced with predominance of excitation, 2) strong well-balanced active with high mobility, 3) strong well-balanced passive with low mobility, and 4) weak with extremely weak excitation and inhibition leading to fatigue. Different nervous system types determine the rate of forming new conditioned reflexes and their strength and stability.
This document outlines a plan for a presentation on inhibition in the central nervous system. It will define inhibition, describe the roles of inhibition in protection and coordination. It will explain excitatory and inhibitory postsynaptic potentials and the major inhibitory neurotransmitters like GABA. It will classify inhibition by location, mechanism, and nature. It will cover topics like lateral, reciprocal, and Renshaw inhibition. It will also discuss Sechenov's pioneering experiment demonstrating central inhibition in the brain. References will be included.
The document discusses the autonomic nervous system (ANS), which controls internal organs and glands. It describes the ANS as having two divisions - the sympathetic and parasympathetic systems. The sympathetic system activates the body's fight or flight response through secretion of epinephrine and norepinephrine from the adrenal medulla. The parasympathetic system acts to slow functions down and return the body to homeostasis. The document provides details on the pathways, targets, and functions of both divisions of the ANS.
NERVOUS REGULATION OF FUNCTIONS . EXCITATION AND INHIBITION IN CNSDeep Patel
This document provides an overview of nervous regulation of functions, including central nervous system excitation and inhibition. It discusses regulatory systems and feedback mechanisms that maintain homeostasis. The key points are:
- The nervous system provides rapid control of body functions through the central nervous system and peripheral nervous system.
- Neurons are the basic structural and functional units, receiving and integrating sensory information and generating motor responses.
- Reflexes are basic response circuits involving afferent neurons, central processing, and efferent motor output. Reflexes coordinate to regulate functions.
- The central nervous system exhibits properties like summation and transformation that allow complex processing and integration of sensory information to coordinate motor functions.
Reflex action provides a rapid, involuntary response to stimuli. A reflex arc consists of a sensory organ, sensory nerve, spinal cord, motor nerve, and effector organ. Reflexes can be classified as clinical, anatomical, based on number of synapses, or functional. Clinical reflexes include superficial, deep, visceral, and pathological reflexes. Anatomical reflexes are segmental, intersegmental, or suprasegmental. Reflexes also differ based on having one, two, or multiple synapses. Functional reflexes include flexor/withdrawal and extensor reflexes. Reflexes can also be unconditional or conditional.
- Animals generate circadian and circannual rhythms that regulate sleep/wake cycles, eating/drinking patterns, temperature, hormone secretion and other functions on 24-hour and yearly cycles respectively.
- Humans have a circadian rhythm slightly longer than 24 hours that is reset by light/dark cues. Disruption of circadian rhythms can cause jet lag. The suprachiasmatic nucleus regulates circadian rhythms.
- Sleep stages include NREM (stages 1-4) and REM sleep. REM is characterized by dreaming and paralysis while NREM deepens across stages 1-4. Sleep aids restoration, energy conservation, memory consolidation and more.
The document discusses the neural challenges associated with occlusion effects when wearing hearing aids. It defines non-acoustic/neural occlusion as sensations in the body from hearing aids whether they are on or off. This is believed to be caused by pressure on the nerves of the outer ear. It involves four cranial nerves and two cervical nerves that innervate the outer ear and may cause symptoms away from the ears like headaches or neck tension. Individual variability in nerve pathways means occlusion effects will vary between people.
The neurophysiology of posture and movement. Its postural framework and CNS structures involved in the control of postural movement and postural reflexes. The influence of muscle tone on posture.
1) The cerebellum is vital for controlling rapid movements and coordinating muscle activity. Damage impairs smooth, coordinated movements rather than causing paralysis.
2) The cerebellum is divided into three main phylogenetic subdivisions - spinocerebellum, pontocerebellum, and vestibulocerebellum - each with different anatomical parts and roles.
3) The cerebellum receives input from various sources and outputs to deep cerebellar nuclei that project to motor areas, regulating movement. Damage results in ipsilateral movement deficits.
The document discusses the organization and components of the human nervous system. It describes the central nervous system, peripheral nervous system, and autonomic nervous system. It also discusses the classification and structure of neurons and nerve fibers, as well as the roles of neuroglia and synapses. Key topics covered include the histology of nervous tissue, types of neurotransmitters and receptors, and the functions of structures like the myelin sheath.
Spinal cord reflexes involve a reflex arc with an afferent limb, efferent limb, and central nervous system center. Reflexes can be classified as clinical (based on stimulus location), anatomical (based on spinal cord location), physiological (based on muscle response), or based on innate versus learned response. Examples of reflexes include the stretch reflex, withdrawal reflex, and crossed extensor reflex. Spinal reflexes integrate afferent and efferent signaling without brain involvement.
This document provides an overview of sleep, its stages, circadian rhythms, and relationship to anesthesia. It defines sleep and describes its typical stages: non-rapid eye movement (NREM) sleep including stages 1-3, and rapid eye movement (REM) sleep. NREM sleep involves slow brain waves and restoration, while REM involves dreaming and autonomic instability. Circadian rhythms regulate daily cycles of activity and rest and are generated by biological clocks in cells. Perioperative sleep deprivation and sleep disorders like sleep apnea can impact patient outcomes, making sleep important for anesthesia.
The document discusses different types of reflexes in the human body, including inborn/intrinsic reflexes which are involuntary responses to stimuli and help maintain basic functions, and learned/acquired reflexes which develop over time through repetition. It describes the components of the reflex arc, including receptors, sensory and motor neurons, integration centers, and effectors. Specific reflexes are discussed in detail such as the stretch reflex, knee jerk reflex, reciprocal inhibition, and plantar reflex. The roles of muscle spindles, gamma motor neurons, and Golgi tendon organs in reflexes are also explained.
The reticular formation is a network of neurons located in the brainstem that serves several important functions:
1. It helps regulate arousal and consciousness through the reticular activating system. This system projects to the thalamus and maintains an alert cerebral cortex. Damage can result in coma.
2. It modulates muscle tone through facilitatory and inhibitory projections to the spinal cord. The pontine reticular formation facilitates antigravity muscles while the medullary region inhibits them.
3. In addition to arousal and motor control, the reticular formation is involved in other autonomic functions like respiration, cardiovascular regulation, vomiting, coughing, and processing pain signals.
Neuroplasticity refers to the brain's ability to change and reorganize itself in response to experience. The brain forms new connections and pathways when we learn new skills or have new experiences. Neuroplasticity allows the brain to compensate for injury and disease and is responsible for development throughout childhood. Promising therapies that may enhance neuroplasticity include brain stimulation, cognitive training, and certain drugs. Assessing neuroplasticity in humans through biomarkers can help predict treatment response and monitor recovery. Harnessing neuroplasticity is key for rehabilitation from brain injuries and disorders.
The document discusses the reticular activating system (RAS), which is a network of neurons in the brainstem that regulates states of consciousness and sleep-wake cycles. Stimulation of different areas of the reticular formation can increase or decrease spinal reflexes. The RAS includes noradrenergic, dopaminergic, serotonergic, and cholinergic neurons that project ascending signals to the thalamus and cortex. Damage to parts of the RAS can impair consciousness. Sleep involves circadian rhythms and cycles through non-REM and REM sleep stages, each with different patterns of neuronal activity and physiological changes.
The brainstem controls movement through three motor pathways - the medial, lateral, and corticospinal pathways. The medial pathway controls posture and arises from the reticular formation, vestibular nuclei and tectum. The lateral pathway controls limb movements and arises from the red nucleus. The corticospinal pathway provides precise control of individual muscles and arises from the motor cortex. Damage to upper motor neurons can cause either negative signs like weakness or positive signs like increased muscle tone.
Postural reflexes help maintain an upright and balanced body position during both static and dynamic activities. They involve reflex arcs with receptors in the eyes, vestibular system and proprioceptors, integrating centers in the brainstem and spinal cord, and motor neurons activating skeletal muscles. There are two types of postural reflexes - static reflexes which adjust for gravitational displacements, and statokinetic reflexes which aid balance during voluntary movement. Important static reflexes include the stretch reflex, tonic labyrinthine reflex and tonic neck reflex.
This document discusses reflexes and the reflex arc. It defines a reflex arc as the anatomical nervous pathway of a reflex, consisting of 5 components: receptor, sensory neuron, integration center, motor neuron, and effector. It describes stretch reflexes, including the dynamic stretch reflex activated by changes in muscle length and the static stretch reflex maintaining constant muscle tone. Various types of reflexes are classified, including superficial, deep, and visceral reflexes. Clinical uses of assessing reflexes are also discussed.
The Reticular Activating System (RAS) is a network of neurons that extends from the brainstem to different parts of the brain and spinal cord. It functions to regulate arousal, alertness, and selective attention by increasing or decreasing activity and directing cortical areas to focus on relevant information. Destroying the RAS causes a coma similar to sleep, while stimulating it instantly awakens sleeping animals. The Thalamus filters and relays incoming sensory information, with the exception of smell, to cortical areas. It plays a role in attention by emphasizing certain information and regulates arousal through its connection to the RAS.
The document summarizes research on the thalamic connections of the primary motor cortex in owl monkeys. Three key findings are:
1) The strongest connections are between M1 and subdivisions of the ventral lateral thalamus, particularly the principal, medial, and anterior subdivisions.
2) The connections are topographically organized such that different body part representations in M1 connect to distinct bands within the thalamus.
3) While caudal M1 connects strongly with the principal subdivision, rostral M1 connects more with the anterior subdivision.
The document discusses physiological mechanisms and behavior from the perspective of the nervous system and hormones. It provides details on the evolution of the nervous system across organisms from unicellular to multicellular to vertebrates. Key points made include the increasing differentiation and centralization of the nervous system correlating with increased behavioral complexity. Examples are given comparing nervous system anatomy and organization between invertebrate and vertebrate species in relation to different lifestyles and behaviors.
The document discusses the structure and function of the human neural and sensory systems. It describes the central nervous system including the brain, spinal cord, and peripheral nervous system. It explains the divisions of the brain including the forebrain, midbrain, and hindbrain. It also discusses the autonomic nervous system and its sympathetic and parasympathetic divisions. Additionally, it summarizes the structure and function of the eye and ear as sensory organs.
NERVOUS REGULATION OF FUNCTIONS . EXCITATION AND INHIBITION IN CNSDeep Patel
This document provides an overview of nervous regulation of functions, including central nervous system excitation and inhibition. It discusses regulatory systems and feedback mechanisms that maintain homeostasis. The key points are:
- The nervous system provides rapid control of body functions through the central nervous system and peripheral nervous system.
- Neurons are the basic structural and functional units, receiving and integrating sensory information and generating motor responses.
- Reflexes are basic response circuits involving afferent neurons, central processing, and efferent motor output. Reflexes coordinate to regulate functions.
- The central nervous system exhibits properties like summation and transformation that allow complex processing and integration of sensory information to coordinate motor functions.
Reflex action provides a rapid, involuntary response to stimuli. A reflex arc consists of a sensory organ, sensory nerve, spinal cord, motor nerve, and effector organ. Reflexes can be classified as clinical, anatomical, based on number of synapses, or functional. Clinical reflexes include superficial, deep, visceral, and pathological reflexes. Anatomical reflexes are segmental, intersegmental, or suprasegmental. Reflexes also differ based on having one, two, or multiple synapses. Functional reflexes include flexor/withdrawal and extensor reflexes. Reflexes can also be unconditional or conditional.
- Animals generate circadian and circannual rhythms that regulate sleep/wake cycles, eating/drinking patterns, temperature, hormone secretion and other functions on 24-hour and yearly cycles respectively.
- Humans have a circadian rhythm slightly longer than 24 hours that is reset by light/dark cues. Disruption of circadian rhythms can cause jet lag. The suprachiasmatic nucleus regulates circadian rhythms.
- Sleep stages include NREM (stages 1-4) and REM sleep. REM is characterized by dreaming and paralysis while NREM deepens across stages 1-4. Sleep aids restoration, energy conservation, memory consolidation and more.
The document discusses the neural challenges associated with occlusion effects when wearing hearing aids. It defines non-acoustic/neural occlusion as sensations in the body from hearing aids whether they are on or off. This is believed to be caused by pressure on the nerves of the outer ear. It involves four cranial nerves and two cervical nerves that innervate the outer ear and may cause symptoms away from the ears like headaches or neck tension. Individual variability in nerve pathways means occlusion effects will vary between people.
The neurophysiology of posture and movement. Its postural framework and CNS structures involved in the control of postural movement and postural reflexes. The influence of muscle tone on posture.
1) The cerebellum is vital for controlling rapid movements and coordinating muscle activity. Damage impairs smooth, coordinated movements rather than causing paralysis.
2) The cerebellum is divided into three main phylogenetic subdivisions - spinocerebellum, pontocerebellum, and vestibulocerebellum - each with different anatomical parts and roles.
3) The cerebellum receives input from various sources and outputs to deep cerebellar nuclei that project to motor areas, regulating movement. Damage results in ipsilateral movement deficits.
The document discusses the organization and components of the human nervous system. It describes the central nervous system, peripheral nervous system, and autonomic nervous system. It also discusses the classification and structure of neurons and nerve fibers, as well as the roles of neuroglia and synapses. Key topics covered include the histology of nervous tissue, types of neurotransmitters and receptors, and the functions of structures like the myelin sheath.
Spinal cord reflexes involve a reflex arc with an afferent limb, efferent limb, and central nervous system center. Reflexes can be classified as clinical (based on stimulus location), anatomical (based on spinal cord location), physiological (based on muscle response), or based on innate versus learned response. Examples of reflexes include the stretch reflex, withdrawal reflex, and crossed extensor reflex. Spinal reflexes integrate afferent and efferent signaling without brain involvement.
This document provides an overview of sleep, its stages, circadian rhythms, and relationship to anesthesia. It defines sleep and describes its typical stages: non-rapid eye movement (NREM) sleep including stages 1-3, and rapid eye movement (REM) sleep. NREM sleep involves slow brain waves and restoration, while REM involves dreaming and autonomic instability. Circadian rhythms regulate daily cycles of activity and rest and are generated by biological clocks in cells. Perioperative sleep deprivation and sleep disorders like sleep apnea can impact patient outcomes, making sleep important for anesthesia.
The document discusses different types of reflexes in the human body, including inborn/intrinsic reflexes which are involuntary responses to stimuli and help maintain basic functions, and learned/acquired reflexes which develop over time through repetition. It describes the components of the reflex arc, including receptors, sensory and motor neurons, integration centers, and effectors. Specific reflexes are discussed in detail such as the stretch reflex, knee jerk reflex, reciprocal inhibition, and plantar reflex. The roles of muscle spindles, gamma motor neurons, and Golgi tendon organs in reflexes are also explained.
The reticular formation is a network of neurons located in the brainstem that serves several important functions:
1. It helps regulate arousal and consciousness through the reticular activating system. This system projects to the thalamus and maintains an alert cerebral cortex. Damage can result in coma.
2. It modulates muscle tone through facilitatory and inhibitory projections to the spinal cord. The pontine reticular formation facilitates antigravity muscles while the medullary region inhibits them.
3. In addition to arousal and motor control, the reticular formation is involved in other autonomic functions like respiration, cardiovascular regulation, vomiting, coughing, and processing pain signals.
Neuroplasticity refers to the brain's ability to change and reorganize itself in response to experience. The brain forms new connections and pathways when we learn new skills or have new experiences. Neuroplasticity allows the brain to compensate for injury and disease and is responsible for development throughout childhood. Promising therapies that may enhance neuroplasticity include brain stimulation, cognitive training, and certain drugs. Assessing neuroplasticity in humans through biomarkers can help predict treatment response and monitor recovery. Harnessing neuroplasticity is key for rehabilitation from brain injuries and disorders.
The document discusses the reticular activating system (RAS), which is a network of neurons in the brainstem that regulates states of consciousness and sleep-wake cycles. Stimulation of different areas of the reticular formation can increase or decrease spinal reflexes. The RAS includes noradrenergic, dopaminergic, serotonergic, and cholinergic neurons that project ascending signals to the thalamus and cortex. Damage to parts of the RAS can impair consciousness. Sleep involves circadian rhythms and cycles through non-REM and REM sleep stages, each with different patterns of neuronal activity and physiological changes.
The brainstem controls movement through three motor pathways - the medial, lateral, and corticospinal pathways. The medial pathway controls posture and arises from the reticular formation, vestibular nuclei and tectum. The lateral pathway controls limb movements and arises from the red nucleus. The corticospinal pathway provides precise control of individual muscles and arises from the motor cortex. Damage to upper motor neurons can cause either negative signs like weakness or positive signs like increased muscle tone.
Postural reflexes help maintain an upright and balanced body position during both static and dynamic activities. They involve reflex arcs with receptors in the eyes, vestibular system and proprioceptors, integrating centers in the brainstem and spinal cord, and motor neurons activating skeletal muscles. There are two types of postural reflexes - static reflexes which adjust for gravitational displacements, and statokinetic reflexes which aid balance during voluntary movement. Important static reflexes include the stretch reflex, tonic labyrinthine reflex and tonic neck reflex.
This document discusses reflexes and the reflex arc. It defines a reflex arc as the anatomical nervous pathway of a reflex, consisting of 5 components: receptor, sensory neuron, integration center, motor neuron, and effector. It describes stretch reflexes, including the dynamic stretch reflex activated by changes in muscle length and the static stretch reflex maintaining constant muscle tone. Various types of reflexes are classified, including superficial, deep, and visceral reflexes. Clinical uses of assessing reflexes are also discussed.
The Reticular Activating System (RAS) is a network of neurons that extends from the brainstem to different parts of the brain and spinal cord. It functions to regulate arousal, alertness, and selective attention by increasing or decreasing activity and directing cortical areas to focus on relevant information. Destroying the RAS causes a coma similar to sleep, while stimulating it instantly awakens sleeping animals. The Thalamus filters and relays incoming sensory information, with the exception of smell, to cortical areas. It plays a role in attention by emphasizing certain information and regulates arousal through its connection to the RAS.
The document summarizes research on the thalamic connections of the primary motor cortex in owl monkeys. Three key findings are:
1) The strongest connections are between M1 and subdivisions of the ventral lateral thalamus, particularly the principal, medial, and anterior subdivisions.
2) The connections are topographically organized such that different body part representations in M1 connect to distinct bands within the thalamus.
3) While caudal M1 connects strongly with the principal subdivision, rostral M1 connects more with the anterior subdivision.
The document discusses physiological mechanisms and behavior from the perspective of the nervous system and hormones. It provides details on the evolution of the nervous system across organisms from unicellular to multicellular to vertebrates. Key points made include the increasing differentiation and centralization of the nervous system correlating with increased behavioral complexity. Examples are given comparing nervous system anatomy and organization between invertebrate and vertebrate species in relation to different lifestyles and behaviors.
The document discusses the structure and function of the human neural and sensory systems. It describes the central nervous system including the brain, spinal cord, and peripheral nervous system. It explains the divisions of the brain including the forebrain, midbrain, and hindbrain. It also discusses the autonomic nervous system and its sympathetic and parasympathetic divisions. Additionally, it summarizes the structure and function of the eye and ear as sensory organs.
The brain is one of the largest and most complex organs in the human body. It is made up of more than 100 billion nerves that communicate in trillions of connections called synapses. The brain is made up of many specialized areas that work together: ... The cortex is the outermost layer of brain cells. the brain is how you think.
The human nervous system develops from the neural tube during early embryogenesis. Neurons differentiate and grow axons that connect with other neurons. The central nervous system develops from the neural tube, with the brain and spinal cord forming. The brain is made up of several specialized regions including the cerebral hemispheres, cerebellum, and brainstem. The cerebral cortex has evolved in humans to have extensive folding and the largest surface area, allowing for more complex functions.
This document provides an overview of the physiology of sleep. It discusses the regulation and definition of sleep, the stages of sleep including REM and NREM sleep, and the electrophysiological criteria for sleep stages. It also summarizes the organization of sleep in adults, the effects of sleep on various body systems like the autonomic nervous system and neuroendocrine system. Finally, it outlines the neurobiology of sleep and wakefulness including the roles of the reticular activating system, hypocretin, VLPO area, and other sleep-promoting substances.
The reticular formation is a network of neurons located in the brainstem that serves important functions. It extends from the spinal cord up through the midbrain. The reticular formation receives input from various areas of the brain and spinal cord and sends output to many regions including the thalamus and cerebral cortex. It is involved in arousal, motor control, sensory processing, sleep-wake cycles and other vital functions through the ascending and descending reticular activating systems. Damage to or disruption of the reticular formation can impact consciousness, muscle tone, learning, and circadian rhythms.
This document provides an outline of topics related to neurons and the nervous system. It begins by discussing the evolution of the nervous system, noting the gradual increase in complexity and that all vertebrates have a well-developed brain. It then covers nervous tissue, the brain and spinal cord, peripheral nervous system, invertebrate and vertebrate nervous organization, and the specific human nervous system including the central and peripheral components.
The limbic system and reticular formation are brain structures involved in emotion, learning, memory, and behavior. The limbic system includes the hippocampus, amygdala, and surrounding cortical areas. It regulates emotions, expression of feelings, fear responses, and memory formation. The reticular formation is a diffuse network in the brainstem that maintains arousal, muscle tone, sleep-wake cycles, and modulates pain perception. Together these structures form circuits that are important for basic functions and are implicated in various psychiatric conditions.
The document discusses the structure and function of the nervous system. It describes how the nervous system is composed of nervous tissue, including neurons and neuroglial cells. Neurons are the conducting cells that send and receive signals, while neuroglial cells provide support and insulation. The document outlines the key cell types, their roles, and organizational structure of the central and peripheral nervous systems.
The document describes the structure and function of the nervous system. It discusses the central nervous system (CNS), which includes the brain and spinal cord, and the peripheral nervous system (PNS), which includes nerves that connect the CNS to the rest of the body. It describes the functions of neurons and neuroglial cells that make up nervous tissue and help transmit signals. Specifically, it discusses the roles of astrocytes, oligodendrocytes, microglia, and Schwann cells. It also explains the functions of the somatic, autonomic, and enteric nervous systems and how they regulate voluntary and involuntary bodily processes.
The basal ganglia function in close association with the cerebral cortex to facilitate motor control and learning. They receive input from widespread areas of the cortex and have direct and indirect pathways that utilize GABA and dopamine to balance movement. Disruption of this balance, as seen in Parkinson's disease due to dopamine deficiency, results in both hypokinetic and hyperkinetic movement abnormalities. The cerebellum integrates sensory information to coordinate proprioception, balance, and fine motor control through connections with deep nuclei and brainstem.
The autonomic nervous system controls internal organs and glands. It has both sympathetic and parasympathetic divisions. The sympathetic division uses norepinephrine and epinephrine to activate the fight or flight response. The parasympathetic uses acetylcholine for rest and digest functions. Both have preganglionic and postganglionic neurons. The autonomic nervous system regulates vital involuntary functions like heart rate, breathing, digestion and pupillary response.
UROTRANSMITTERS-NEUROMODULATORS
More than 50 chemical substances
1.Small molecules with rapid effects
Stored in axonal vesicules
Effect on postsynaptic membrane approx. 1 ms, -opening of ion channels,
Brief inactivation, recycled, fromed in the body of neurons
Class I. ACH
Class II. Amines : NA, A, Dopamin, serotonin, histamin
Class III. Aminoacids: GABA, Glycin, Glutamate, Aspartate
Class IV. NO
2. NEUROPEPTIDES,prolonged effects, are integral part of protein molecules
In neuronal bodies, are fromed in the bodies and compose the vesicules inside of them,
then they are brought to the axonal terminals with longlasting effect (hours -days)
Modulates the expression of genes
A.Hypothalamic releasing hormones
B.Pituitary peptides: beta-endorfin, MSH, Prolactin, GH, vasopresin, oxytocin,
ACTH, LH, TSH
C. Peptides operating in GIT and brain:Leucin, enkefalin, methionin
substance P, gastrin, cholecystokinin, VIP, neurotensin, insulin, glucagon
D. From other tissues: angiotensin II, Bradykinin, Carnosin, calcitonin, sleep peptides Peptides operating in GIT and brain:Leucin, enkefalin, methionin
substance P, gastrin, cholecystokinin, VIP, neurotensin, insulin, glucagon
D. From other tissues: angiotensin II, Bradykinin, Carnosin, calcitonin, sleep peptides you are operating in GIT and brain:Leucin, enkefalin, methionin
substance P, gastrin, cholecystokinin, VIP, neurotensin, insulin, glucagon
D. From other tissues: angiotensin II, Bradykinin, Carnosin, calcitonin, sleep peptides you
The autonomic nervous system regulates involuntary body functions like heart rate, respiration, digestion and more. It has two divisions:
The sympathetic nervous system prepares the body for "fight or flight" through responses like increased heart rate and dilated pupils. It uses norepinephrine as a neurotransmitter.
The parasympathetic nervous system helps the body "rest and digest" with functions like digestion, salivation and pupil constriction. It uses acetylcholine as a neurotransmitter.
Together these two divisions work to maintain homeostasis and control internal organs through a two-neuron pathway, with cell bodies located in the spinal cord or brainstem and ganglia between pre- and postganglionic neurons.
The document discusses the autonomic nervous system, which has two divisions - the sympathetic and parasympathetic systems. The sympathetic system prepares the body for fight or flight by increasing heart rate and blood pressure. The parasympathetic system then takes over once the stressor is gone, calming the body down.
The facial nerve is the seventh cranial nerve. It emerges from the brainstem between the pons and medulla and controls the muscles of facial expression and taste to the front two-thirds of the tongue. The facial nerve has motor, sensory, and parasympathetic components. It innervates the muscles of facial expression and provides parasympathetic fibers to salivary and lacrimal glands.
The lecture discusses the anatomy and functions of the autonomic nervous system, specifically the sympathetic and parasympathetic divisions. It describes the central and peripheral structures of these systems, including sympathetic centers in the brain and spinal cord, and ganglia in the periphery. The sympathetic system activates the fight or flight response and increases heart rate and respiration. It diverts blood flow away from the digestive system. The parasympathetic system stimulates rest and digestion functions like salivation and digestion.
The lecture discusses the anatomy and functions of the autonomic nervous system, specifically the sympathetic and parasympathetic divisions. It describes the central and peripheral structures of these systems, including sympathetic centers in the brain and spinal cord, and ganglia in the periphery. The sympathetic system activates the fight or flight response and increases heart rate and respiration. It diverts blood flow away from the digestive system. The parasympathetic system stimulates rest and digestion functions like salivation and digestion.
The document provides an overview of the nervous system, including its organization and major components. It discusses the central nervous system (CNS), which includes the brain and spinal cord, and the peripheral nervous system (PNS). Key topics covered include the structure and function of neurons, types of neurons, nerve impulses, and synaptic transmission. The major divisions and structures of the brain are outlined. The role of the spinal cord and reflex arcs are also summarized.
Similar to Functions of Diencephalon & Subcortical Ganglia (20)
The document discusses the benefits of exercise for mental health. Regular physical activity can help reduce anxiety and depression and improve mood and cognitive functioning. Exercise causes chemical changes in the brain that may help protect against mental illness and improve symptoms.
The document discusses the benefits of exercise for mental health. Regular physical activity can help reduce anxiety and depression and improve mood and cognitive function. Exercise causes chemical changes in the brain that may help protect against mental illness and improve symptoms for those who already suffer from conditions like anxiety and depression.
The document discusses the benefits of exercise for mental health. Regular physical activity can help reduce anxiety and depression and improve mood and cognitive functioning. Exercise boosts blood flow, releases endorphins, and promotes changes in the brain which help enhance one's emotional well-being and mental clarity.
The document discusses the benefits of exercise for mental health. Regular physical activity can help reduce anxiety and depression and improve mood and cognitive functioning. Exercise causes chemical changes in the brain that may help boost feelings of calmness, happiness and focus.
The document discusses the benefits of exercise for mental health. Regular physical activity can help reduce anxiety and depression and improve mood and cognitive function. Exercise causes chemical changes in the brain that may help protect against mental illness and improve symptoms for those who already suffer from conditions like anxiety and depression.
The document discusses the benefits of exercise for mental health. Regular physical activity can help reduce anxiety and depression and improve mood and cognitive function. Exercise causes chemical changes in the brain that may help protect against mental illness and improve symptoms for those who already suffer from conditions like anxiety and depression.
The document discusses the benefits of exercise for mental health. Regular physical activity can help reduce anxiety and depression and improve mood and cognitive functioning. Exercise causes chemical changes in the brain that may help protect against mental illness and improve symptoms.
The document provides information about the Post Graduate Common Entrance Test to be held on July 1st, 2017 from 2:30 pm to 4:30 pm for various Masters programs. It lists instructions for candidates regarding filling the answer sheet correctly and details about the structure of the test, which will consist of 75 multiple choice questions worth 100 marks to be completed within 120 minutes. Candidates are advised to carefully read and follow the guidelines for appearing in the exam.
Civil Service 2019 Prelims Previous Question Paper - 2Eneutron
The document discusses the benefits of exercise for mental health. Regular physical activity can help reduce anxiety and depression and improve mood and cognitive function. Exercise causes chemical changes in the brain that may help protect against mental illness and improve symptoms.
Civil Service 2019 Prelims Previous Question Paper - 1Eneutron
The document discusses the benefits of exercise for mental health. Regular physical activity can help reduce anxiety and depression and improve mood and cognitive function. Exercise causes chemical changes in the brain that may help protect against mental illness and improve symptoms.
Civil Service 2018 Prelims Previous Question Paper - 2Eneutron
The document discusses the benefits of exercise for mental health. Regular physical activity can help reduce anxiety and depression and improve mood and cognitive functioning. Exercise causes chemical changes in the brain that may help protect against mental illness and improve symptoms.
Civil Service 2018 Prelims Previous Question Paper - 1Eneutron
The document discusses the benefits of exercise for mental health. Regular physical activity can help reduce anxiety and depression and improve mood and cognitive functioning. Exercise causes chemical changes in the brain that may help protect against mental illness and improve symptoms.
Civil Service 2017 Prelims Previous Question Paper - 2Eneutron
The document discusses the benefits of exercise for mental health. Regular physical activity can help reduce anxiety and depression and improve mood and cognitive function. Exercise causes chemical changes in the brain that may help protect against mental illness and improve symptoms for those who already suffer from conditions like depression and anxiety.
Civil Service 2017 Prelims Previous Question Paper - 1Eneutron
The document discusses the benefits of exercise for mental health. Regular physical activity can help reduce anxiety and depression and improve mood and cognitive function. Exercise stimulates the production of endorphins in the brain which elevate mood and reduce stress levels.
This document contains the question paper for SNAP 2013 along with the answers to the 150 multiple choice questions. It directs test takers to an online site to attempt previous SNAP papers and provides information about exam preparation resources available on the site such as daily practice questions, preparation strategies, coaching classes, and current affairs.
This document contains the question paper for SNAP 2014 along with the answers to the 150 multiple choice questions. It provides a link to attempt similar past year papers online and lists exam preparation resources for SNAP like daily practice questions, preparation strategies, coaching class recommendations, and current affairs.
Basavarajeeyam is an important text for ayurvedic physician belonging to andhra pradehs. It is a popular compendium in various parts of our country as well as in andhra pradesh. The content of the text was presented in sanskrit and telugu language (Bilingual). One of the most famous book in ayurvedic pharmaceutics and therapeutics. This book contains 25 chapters called as prakaranas. Many rasaoushadis were explained, pioneer of dhatu druti, nadi pareeksha, mutra pareeksha etc. Belongs to the period of 15-16 century. New diseases like upadamsha, phiranga rogas are explained.
Histololgy of Female Reproductive System.pptxAyeshaZaid1
Dive into an in-depth exploration of the histological structure of female reproductive system with this comprehensive lecture. Presented by Dr. Ayesha Irfan, Assistant Professor of Anatomy, this presentation covers the Gross anatomy and functional histology of the female reproductive organs. Ideal for students, educators, and anyone interested in medical science, this lecture provides clear explanations, detailed diagrams, and valuable insights into female reproductive system. Enhance your knowledge and understanding of this essential aspect of human biology.
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Rasamanikya is a excellent preparation in the field of Rasashastra, it is used in various Kushtha Roga, Shwasa, Vicharchika, Bhagandara, Vatarakta, and Phiranga Roga. In this article Preparation& Comparative analytical profile for both Formulationon i.e Rasamanikya prepared by Kushmanda swarasa & Churnodhaka Shodita Haratala. The study aims to provide insights into the comparative efficacy and analytical aspects of these formulations for enhanced therapeutic outcomes.
Does Over-Masturbation Contribute to Chronic Prostatitis.pptxwalterHu5
In some case, your chronic prostatitis may be related to over-masturbation. Generally, natural medicine Diuretic and Anti-inflammatory Pill can help mee get a cure.
2. THALAMUSTHALAMUS
Consists of about 40 nuclei which areConsists of about 40 nuclei which are
divided functionally into groupsdivided functionally into groups
3. I.I. SPECIFIC OR RELAYSPECIFIC OR RELAY
NUCLEINUCLEI
Lateral geniculate body (LGB) –Lateral geniculate body (LGB) –
visual modalityvisual modality
Medial geniculate body (MGB)Medial geniculate body (MGB)––
auditory modalityauditory modality
Ventro-basilar complex (VP) –Ventro-basilar complex (VP) –
somato-sensory modalitysomato-sensory modality
7. Specific nucleiSpecific nuclei
Function – get sensory information fromFunction – get sensory information from
specific pathways & send it to specificspecific pathways & send it to specific
sensory zones of cortex.sensory zones of cortex.
Topical organization – each neuron isTopical organization – each neuron is
connected with specific receptive fieldconnected with specific receptive field
8. Lateral inhibition in thalamus helpsLateral inhibition in thalamus helps
to cut off aberration & defineto cut off aberration & define
important sensory signal –important sensory signal –
information
Goldgi neurons
Afferent
neurons
9. IIII MOTOR NUCLEUSMOTOR NUCLEUS
ventrolateral (VL)ventrolateral (VL)
Is included in the system of movemntIs included in the system of movemnt
regulation.regulation.
Gets impulses from cerebellum & basalGets impulses from cerebellum & basal
ganglia.ganglia.
Sends information to motor cortex (pre-Sends information to motor cortex (pre-
central gyrus).central gyrus).
11. IIIIII ASSOCIATIVE NUCLEIASSOCIATIVE NUCLEI
Pulvinar -Pulvinar - is connected with temporal &is connected with temporal &
parietal associative cortexparietal associative cortex
Posterio-lateral nucleus (LP) –Posterio-lateral nucleus (LP) – isis
connected with temporal cortexconnected with temporal cortex
Medio-dorsal nucleus (MP) –Medio-dorsal nucleus (MP) – is connectedis connected
with frontal cortexwith frontal cortex
Anterior nucleus –Anterior nucleus – is connected with limbicis connected with limbic
cortexcortex
12. All associative nuclei are gettingAll associative nuclei are getting
poly-modal signals from:poly-modal signals from:
Specific relay nucleiSpecific relay nuclei
Specific afferent pathwaysSpecific afferent pathways
They are included into the associativeThey are included into the associative
systems of the brain & take part in thesystems of the brain & take part in the
integrative processes forming behaviourintegrative processes forming behaviour
and memory.and memory.
13. IVIV NON-SPRCIFIC NUCLEINON-SPRCIFIC NUCLEI
INTRALAMINAR & MEDIUM GROUP OFINTRALAMINAR & MEDIUM GROUP OF
NUCLEINUCLEI , they are continuation of reticular, they are continuation of reticular
formation of the brain stem and are poly-formation of the brain stem and are poly-
modal because they get information frommodal because they get information from ::
RF of brain stemRF of brain stem
Specific afferent pathwaysSpecific afferent pathways
SpecificSpecific thalamus nucleithalamus nuclei
Send impulses diffusively to all the cortexSend impulses diffusively to all the cortex
zoneszones
14. THALAMUS IS THE HIGHESTTHALAMUS IS THE HIGHEST
CENTER OF PAINCENTER OF PAIN
16. Sensor zones
of cortex
Associative zones
of cortex
Motor zones
of cortex
Sensor information
from receptors
Sensor specific
nuclei
Non-specific nuclei
Associative
nuclei
Cerebellum &
basal ganglia
Motor
nuclei
19. ANATOMICAL PECULIARITIESANATOMICAL PECULIARITIES
GROUS OF NUCLEA ARE NOTGROUS OF NUCLEA ARE NOT
STRICTLY LOCALISEDSTRICTLY LOCALISED
NO BLOOD-BRAIN BARRIERNO BLOOD-BRAIN BARRIER
MULTIPLY CONNECTIONS WITHMULTIPLY CONNECTIONS WITH
OTHER СNS STRUCTURESOTHER СNS STRUCTURES
22. GETTING INFORMATIONGETTING INFORMATION
ABOUT EXTERNAL ENVIRONMENTABOUT EXTERNAL ENVIRONMENT – via– via
nervous connections from thalamus, RF, cortexnervous connections from thalamus, RF, cortex
ABOUT INTERNAL ENVIRONMENTABOUT INTERNAL ENVIRONMENT - from- from
blood & liquor (HEB is very low)blood & liquor (HEB is very low)
Information is received by sensory neuronsInformation is received by sensory neurons
(osmoreceptors, volumoreceptors,(osmoreceptors, volumoreceptors,
glucoreceptors & others),glucoreceptors & others), which process thiswhich process this
info & form sensations.info & form sensations.
23. CENTERS OF SENSATION INCENTERS OF SENSATION IN
HYPOTHALAMUSHYPOTHALAMUS
hunger –hunger – satietysatiety
thirst –thirst – thirst satisfactionthirst satisfaction
sleep-sleep- awakenessawakeness
warmth –warmth – coldcold
aggression –aggression – calmnesscalmness
24. EFFECTOR FUNCTIONSEFFECTOR FUNCTIONS
Formation of emotions & motivation ofFormation of emotions & motivation of
behaviorbehavior due to the connections with limbicdue to the connections with limbic
systemsystem
Give rise to behavioral programsGive rise to behavioral programs
(instincts)(instincts) with the involvement of somatic &with the involvement of somatic &
vegetative NSvegetative NS
Performed by neurons effectorsPerformed by neurons effectors
27. Basal gangliaBasal ganglia
(striopallidum system(striopallidum system))
Are paired structures, grey matter located inAre paired structures, grey matter located in
the white matter of hemispheres between thethe white matter of hemispheres between the
frontal lobes & diencephalonfrontal lobes & diencephalon
28. Striopallidum integrates the functions ofStriopallidum integrates the functions of
associative &motor cortexassociative &motor cortex
Motor cortexAssociative cortex
Striopallidar
system
29. Cortex zones
SENSORY ASSOCIATIVE MOTOR
n. caudatus
putamen
Gl.Pal.
Motor nn.
of thalam.
Brain stem
Subthalamic nucleus
Subst. Nigrum
dopamine
dopamine
30. As it is clear from the scheme the afferentAs it is clear from the scheme the afferent
input gets into striatum, аnd the efferentinput gets into striatum, аnd the efferent
influences are performed by globusinfluences are performed by globus
pallidum alone.pallidum alone.
Due to the connections with motor cortexDue to the connections with motor cortex
via thalamusvia thalamus BG take part in realization ofBG take part in realization of
movement programme.movement programme.
31. Mediators:Mediators:
Substantia nigrum neurons secreteSubstantia nigrum neurons secrete
dopaminedopamine
N.caudatum & claustrum neurons – areN.caudatum & claustrum neurons – are
connected with pallidus, they secreteconnected with pallidus, they secrete
GABAGABA
Cortex neurons send impulses to striatumCortex neurons send impulses to striatum
& secrete& secrete acetylcholineacetylcholine
32.
33. Striopallidum effects:Striopallidum effects:
Activates motor neurons ofActivates motor neurons of flexorsflexors viavia
pyramidal tractspyramidal tracts
Multiply influences on flexors & extensors toneMultiply influences on flexors & extensors tone
via motor neurons of brain stemvia motor neurons of brain stem
Inhibits stretching reflexes влияя на альфа иInhibits stretching reflexes влияя на альфа и
гамма мотонейроны вместе с чернойгамма мотонейроны вместе с черной
субстанцией через двигательные ядрасубстанцией через двигательные ядра
ствола мозгаствола мозга
So striopallidum facilitates the performance ofSo striopallidum facilitates the performance of
such complex movement programs as writing,such complex movement programs as writing,
musical instruments playing,musical instruments playing,
34. Striopallidum effects:Striopallidum effects:
Control of some involuntarily movementsControl of some involuntarily movements
in emotional statesin emotional states
Together with cerebellum helps to keepTogether with cerebellum helps to keep
movement programs & information aboutmovement programs & information about
learnt movementslearnt movements
Regulate the glossary muscles activity toRegulate the glossary muscles activity to
modulate voice & speechmodulate voice & speech
35. STRIOPALLIDAR SYSTEMSTRIOPALLIDAR SYSTEM
FUNCTIONSFUNCTIONS
1.1. Regulation of acurate hand movementsRegulation of acurate hand movements
2.2. Keeping movement programsKeeping movement programs
3.3. Regulation of vegetative functionsRegulation of vegetative functions
4.4. Switches on programs of instinct behaviourSwitches on programs of instinct behaviour
(orientation, defense reflexes).(orientation, defense reflexes).
36. Pathological states at strio-pallidumPathological states at strio-pallidum
affectionaffection
When Substantia Nigrum connections withWhen Substantia Nigrum connections with
subcortical ganglia are affected or at the lacksubcortical ganglia are affected or at the lack
of dopamineof dopamine tremor at resttremor at rest developsdevelops, as well, as well
as other symptoms of Parkinsonismas other symptoms of Parkinsonism
When striatum is affected tremor developsWhen striatum is affected tremor develops
both at rest & during movement (chorea), plusboth at rest & during movement (chorea), plus
hyperkinesiahyperkinesia
37. Pathological signs at strio-Pathological signs at strio-
pallidum affectionpallidum affection
When globus pallidum is affected hypokinesiaWhen globus pallidum is affected hypokinesia
developsdevelops
In rheumatic chorea both hypo -&In rheumatic chorea both hypo -&
hyperkinesias develop, mimic muscles arehyperkinesias develop, mimic muscles are
affected, handwriting is changedaffected, handwriting is changed