Influenza, commonly known as the flu, is a highly contagious respiratory illness caused by influenza viruses. The flu virus spreads through droplets when infected people cough, sneeze or talk. Symptoms include fever, body aches, fatigue and gastrointestinal issues. While the flu can be uncomfortable, it is rarely life-threatening. The best prevention is an annual flu vaccine. Treatment focuses on relieving symptoms with antivirals, pain medications and rest.