Managing Flink operations at GO-JEK involves resource provisioning, isolation, data quality, monitoring, and failovers across multiple clusters and data centers. GO-JEK uses Flink for use cases like surge pricing, API health monitoring, and fraud detection. They developed tools to automate cluster provisioning reducing time by 90%, isolate resources for security and performance, manage data quality with schema changes, monitor multiple clusters, and enable kafka input stream and cluster failovers for resiliency. Chaos engineering experiments also help test systems through disaster simulations and load testing.