The document summarizes developments in Northern Europe during the 16th century, including the Protestant Reformation led by Martin Luther, the impact on art with an increased focus on portraits and genre scenes over religious images, and the work of major artists like Bosch, Bruegel, and Dürer. Key events were Luther nailing his 95 theses in 1517, sparking reforms like salvation through faith alone and translating the Bible into local languages. Artists explored new subjects and styles within the technical developments of printmaking and responded to religious and social changes in Northern Europe during this period.