Extinction refers to the end of a species or group of organisms. A species goes extinct when no living individuals remain. Extinction can occur through natural causes like climate change or competition, or through human activities like habitat destruction and overhunting. Mass extinctions where many species die out simultaneously have occurred throughout history, including five major events in Earth's past. Scientists estimate that human activities are currently driving extinction rates 100 to 1000 times higher than the natural background rate, and up to half of all species could be extinct by 2100 if trends continue.