EBD is sequential, systematic process of addressing a clinical or community relevant problems.
EBD components are;
Clinical expertise
Patient’s preferences & values
Highest level of evidence
This document provides an overview of evidence-based practice (EBP) including its definition, importance, evolution, decision-making process, benefits, and misconceptions. It outlines a 5-step approach to EBP: formulating a question, finding evidence, appraising evidence, applying to practice while considering patient values, and evaluating effectiveness. Various resources and levels of evidence are also defined to help practitioners implement EBP and provide the highest quality, cost-effective care.
This document discusses evidence-based medicine (EBM). EBM aims to integrate clinical expertise with the best available research evidence in clinical decision making. It involves 5 steps: formulating a question, finding evidence, critically appraising the evidence, applying to a patient, and evaluating outcomes. EBM categorizes evidence from randomized controlled trials as the highest level and expert opinion as the lowest level. Recommendations are made based on whether benefits outweigh risks. EBM helps improve quality of care, patient satisfaction, and outcomes.
This document discusses the importance of keeping up to date with medical literature for physicians. It notes that over 10,000 new articles are published per week, making it impossible for doctors to read everything. The document then provides guidance on critically evaluating medical literature, including understanding study designs and assessing validity, results, and applicability. It emphasizes applying a systematic approach to identify relevant information and avoid bias. Specific guidance is provided on appraising different study types, such as randomized trials, diagnostic tests, systematic reviews, cohort studies, and case-control studies.
An introduction to conducting a systematic literature review for social scien...rosie.dunne
An introduction to conducting a systematic literature review for social scientists and health researchers presented by Luke van Rhoon Health Behaviour Change Research Group, School of Psychology, NUI Galway November 2020
The document discusses evidence-based orthodontics. It begins with definitions of evidence and evidence-based dentistry. It then discusses the history and evolution of evidence-based practice from the 19th century to present day. The need for evidence-based orthodontics is described as providing patients with the currently best available care. Clinical scenarios are presented and critically appraised based on evidence from the literature. Different study designs and hierarchies of evidence are reviewed. The importance of evidence-based decision making in orthodontics is emphasized.
This document provides an overview of evidence-based practice (EBP) including its definition, importance, evolution, decision-making process, benefits, and misconceptions. It outlines a 5-step approach to EBP: formulating a question, finding evidence, appraising evidence, applying to practice while considering patient values, and evaluating effectiveness. Various resources and levels of evidence are also defined to help practitioners implement EBP and provide the highest quality, cost-effective care.
This document discusses evidence-based medicine (EBM). EBM aims to integrate clinical expertise with the best available research evidence in clinical decision making. It involves 5 steps: formulating a question, finding evidence, critically appraising the evidence, applying to a patient, and evaluating outcomes. EBM categorizes evidence from randomized controlled trials as the highest level and expert opinion as the lowest level. Recommendations are made based on whether benefits outweigh risks. EBM helps improve quality of care, patient satisfaction, and outcomes.
This document discusses the importance of keeping up to date with medical literature for physicians. It notes that over 10,000 new articles are published per week, making it impossible for doctors to read everything. The document then provides guidance on critically evaluating medical literature, including understanding study designs and assessing validity, results, and applicability. It emphasizes applying a systematic approach to identify relevant information and avoid bias. Specific guidance is provided on appraising different study types, such as randomized trials, diagnostic tests, systematic reviews, cohort studies, and case-control studies.
An introduction to conducting a systematic literature review for social scien...rosie.dunne
An introduction to conducting a systematic literature review for social scientists and health researchers presented by Luke van Rhoon Health Behaviour Change Research Group, School of Psychology, NUI Galway November 2020
The document discusses evidence-based orthodontics. It begins with definitions of evidence and evidence-based dentistry. It then discusses the history and evolution of evidence-based practice from the 19th century to present day. The need for evidence-based orthodontics is described as providing patients with the currently best available care. Clinical scenarios are presented and critically appraised based on evidence from the literature. Different study designs and hierarchies of evidence are reviewed. The importance of evidence-based decision making in orthodontics is emphasized.
This document provides an overview of evidence-based orthodontics. It defines evidence-based orthodontics as integrating the best available research evidence with clinical expertise and patient values. The need for evidence-based orthodontics is that it allows practitioners to provide the currently best care available to patients. Evidence-based orthodontic practice differs from traditional practice by regularly accessing new evidence, identifying risk factors, and providing continuous, patient-centered, and efficient care. Systematic reviews are used to summarize research evidence in an unbiased manner to inform clinical decision making.
Clinical Questions types .
A Hierarchy of Preprocessed Evidence.
EBM definition and value.
Knowledge and Skills Necessary for Optimal Evidence-Based Practice.
Basic computer and internet knowledge for electronic searching of the literature
This document provides guidance on critically analyzing research articles. It begins with background on the rapidly expanding medical literature and challenges of keeping up. It then discusses the different types of studies and offers "cheat sheets" to systematically review articles. For cohort studies, it suggests assessing validity, results and applicability. Key points include checking for objective exposure determination and covariate balance. It provides similar guides for diagnostic tests, prognosis, treatment and meta-analyses. The overall goal is to review articles systematically and focus on methodological validity, clinically meaningful results and applicability to one's practice.
The critical appraisal process examines research to judge its validity and relevance. It involves summarizing key aspects of research articles like the introduction, methods, results and discussion sections. Important tools for appraisal include the PICO method to assess the research question, and CASP checklists tailored to different study designs. Proper appraisal helps identify clinically relevant papers and supports evidence-based decision making.
This document discusses the history and process of scientific peer review. It begins by outlining some of the earliest documented uses of peer review in the 9th century by Ishaq bin Ali Al-Rahawi and in the 18th century by the Royal Society of London. It then describes how peer review evolved in the early 1900s in scientific journals and was facilitated by the introduction of photocopiers. The document outlines different peer review systems and their advantages and disadvantages. It also discusses ways to improve peer review, including the roles of authors, editors, reviewers, and publishers. Overall, the document provides a high-level overview of the development and current state of scientific peer review.
This document provides an overview of quality in scientific research. It defines quality as meeting standards of scientific rigor, such as having a well-defined research question, transparent and reproducible methodology, and unbiased reporting of results. The document discusses research quality standards, validity, quantitative and qualitative research methods, and checklists for standardized research reporting. It also addresses challenges in promoting quality and characteristics of high-quality research.
This document summarizes the key aspects of evaluating clinical trials. In 3 sentences:
Clinical trials aim to determine if new treatments are safe and effective by testing them on people after promising laboratory and animal studies. Different types of clinical trials exist, from uncontrolled to randomized controlled trials, with RCTs being the gold standard as they randomly assign participants to interventions to reduce bias. Properly evaluating trials involves assessing their design, limitations, and results to determine the risk of bias and whether the trial's conclusions are valid and applicable to a specific patient.
The document discusses evidence based medicine (EBM), which uses clinical research and other evidence to guide medical decisions. It defines EBM and outlines its key principles, objectives, and steps. EBM aims to minimize errors and optimize care quality by integrating the best research evidence with clinical expertise and patient values and preferences. The document reviews the contents of EBM, the four steps to applying it including formulating questions and searching evidence, and the merits of EBM in improving patient care and reducing costs. Factors influencing the practice of EBM are also discussed.
Chapter 2
Study Designs
Learning Objectives
• List and define the components of a good
study design
• Compare and contrast observational and
experimental study designs
• Summarize the advantages and disadvantages
of alternative study designs
Learning Objectives
• Describe the key features of a randomized
controlled trial
• Identify the study designs used in public health
and medical studies
Study Designs
• Observational Studies
– Case-series study
– Cross-sectional (prevalence) survey
– Case-control study
– Cohort study
• Experimental Studies
– Randomized Controlled (Clinical) Trial
Inferences
• Observational studies – inferences limited to descriptions
and associations; with carefully designed analysis can
make stronger inferences (statistical adjustment)
• Experimental studies – cause and effect
In ALL studies – need careful definition of disease
(outcome) and exposure (risk factor)
Which Design is Best
• Depends on the study question
• What is current knowledge on topic
• How common is disease (and risk factors)
• How long would study take, what are costs
• Ethical issues
Case Report/Case Series
• Observational study
• Case report: Detailed report of specific
features of case
• Case series: Systematic review of common
features of a small number of cases
• Advantage: Cost-efficient
• Disadvantages: No comparison group, no
specific research question
Case-Series
• Simplest design – description of interesting
observations in a small number of individuals
• Usually case-series do not involve control patients
(i.e., patients free of disease)
• Usually lead to generation of hypotheses for more
formal testing
• Criticisms: not planned – no research hypotheses
Case-Series
• Gottleib (1981) studied 5 young homosexual
men with rare form of pneumonia and other
unusual infections
• Initial report was followed by more series (26
cases in NY and CA; “cluster” in southern CA;
34 cases among Haitians, etc.)
• Condition termed AIDS in 1982
Cross-Sectional Survey
• Observational study conducted at a point in
time
• Advantages: Cost-efficient, easy to implement,
ethical
• Disadvantages: No temporal information, non-
response bias
Cross-Sectional Survey
• Is there an association between diabetes and
cardiovascular disease (CVD)?
Patients
with
Diabetes
Patients without
Diabetes
Patients with
CVD
Prospective Cohort Study
• Observational study involving a group (cohort)
of individuals who meet inclusion criteria
followed prospectively in time for risk factor
and outcome information
• Advantages: Can assess temporal relationships
• Disadvantages: Need large numbers for rare
outcomes, confounding
Cohort Study
• Is there an association between hypertension and
cardiovascular disease?
CVD
Hypertension
No CVD
Cohort
CVD
No Hypertension
No CVD
Study Start Time
Cohort Studies
• Identify a group of individuals that meet
inclusion crit ...
Critical appraisal of a journal articleDrSahilKumar
This document provides guidance on critically appraising journal articles. It defines critical appraisal as systematically identifying the strengths and weaknesses of research to assess validity and usefulness. Key aspects to evaluate include relevance of the research question, appropriateness of study design, addressing biases, adherence to original protocol, statistical analyses, and conflicts of interest. Checklists like CASP, CONSORT, and STROBE provide frameworks to appraise study methodologies like randomized trials, systematic reviews, and observational studies. The goal of critical appraisal is for clinicians to identify high-quality evidence to inform clinical practice.
1) The document summarizes key aspects of evaluating clinical trials, including types of trials and potential biases.
2) Clinical trials aim to test interventions in a controlled manner to determine safety and effectiveness. Randomized controlled trials (RCTs) are considered the gold standard for limiting biases.
3) However, biases can still influence trials in many ways, such as through selection of participants, administration of interventions, measurement of outcomes, and reporting/publication of results. It is important to critically appraise trials to assess risk of biases.
Workshop Part 2: Publication Ethics for Biomedical Researchers (BioMed Centra...balaram_biomedcentral
The second presentation in the 2015 BioMed Central author workshop presented at institutions in Brazil.
In this segment, Dr. Maria Kowalczuk, Biology Editor, shares information on research ethics and publication ethics, drawing from her experience as a member of the BioMed Central Research Integrity Group.
This document outlines an agenda for a class on critically appraising medical literature. It begins with reviewing the health science research process and types of research studies. It then discusses what a critical appraisal is and how to appraise a research paper. Key questions to ask when appraising medical literature are presented. The document reviews levels of evidence and study types like randomized controlled trials, cohort studies, and case-control studies. It provides guidance on critically appraising diagnostic studies, intervention studies, and calculating p-values. An in-class appraisal activity is planned to conclude the session.
Interested in a tool to appraise all types of public health evidence?
Do you appraise public health evidence? Are you interested in a single tool that can appraise many different types of evidence and study designs? Join us for a webinar to learn about the MetaQAT.
This tool was developed by Public Health Ontario.
How can the MetaQAT help you?
Many different types of evidence and study designs may be used to answer a single public health question. The MetaQAT provides a single process that can be used to appraise these different types of evidence. This supports the use of evidence to formulate recommendations and develop public health actions.
The MetaQAT consists of a four domain appraisal framework that includes relevance, reliability, validity, and applicability. A suite of design-specific companion tools are included to provide further guidance to assess validity of common designs.
This webinar includes an overview of the MetaQAT by its developer, Dr. Laura Rosella, followed by a presentation from Dr. Catherine Bornbaum, who used the MetaQAT in conducting a systematic review.
To see the summary statement of this tool developed by NCCMT, click here: http://www.nccmt.ca/resources/search/243
The National Collaborating Centre for Methods and Tools is funded by the Public Health Agency of Canada and affiliated with McMaster University. The views expressed herein do not necessarily represent the views of the Public Health Agency of Canada.
NCCMT is one of six National Collaborating Centres (NCCs) for Public Health. The Centres promote and improve the use of scientific research and other knowledge to strengthen public health practices and policies in Canada.
This document outlines the key principles of evidence-based medicine (EBM). EBM uses clinical expertise and the best available research evidence to make decisions about patient care. It involves four main steps: formulating a clinical question based on a patient's situation, searching for the best evidence to answer the question, critically appraising the evidence for validity and usefulness, and applying the results to the patient. EBM aims to minimize errors and optimize quality in patient care by providing a rigorous framework for clinical decision making based on available research evidence. Factors that influence the practice of EBM include the large volume of available literature, difficulties synthesizing evidence and translating it to specific patients, and the increasing number of randomized controlled trials.
Sources of medical knowledge (1 october 2012)jgdaams
This document discusses various resources for finding scientific medical information, including their strengths and limitations. It covers searching the internet, peer-reviewed journals and articles, books, catalogs, bibliographic databases, and clinical practice guidelines. For journals and articles, it discusses assessing quality through metrics like the Journal Impact Factor as well as open access. When searching bibliographic databases, it notes that PubMed contains more records than MEDLINE alone. Overall, the document provides an overview of key sources for medical evidence and factors to consider when evaluating them.
This document discusses evidence-based medicine (EBM). It defines EBM as integrating the best available clinical research with individual expertise and patient values. EBM involves using a hierarchy of evidence, with randomized controlled trials considered the gold standard, to make informed healthcare decisions. Systematic reviews and meta-analyses also provide high-level evidence by comprehensively analyzing available studies. The key aspects of EBM are asking questions, acquiring evidence, appraising studies, applying evidence to individual cases, and assessing outcomes. EBM aims to optimize patient care through minimizing errors and reducing costs by ensuring treatment is based on the most valid and applicable research available.
The document discusses identifying bias in scientific studies. It states that good science minimizes bias through random sampling, minimizing measurement bias, and accounting for multiple factors. Bias can come from the language used, data reported, and source of the data. The scientific community engages in quality control like independent duplication of results and peer review to eliminate bias.
The document discusses identifying bias in scientific studies. It states that good science minimizes bias through random sampling, minimizing measurement bias, and having a large enough sample size. Bias can influence results and different scientists may find different solutions to the same problem. The scientific community engages in quality control like independent duplication of studies and peer review to eliminate bias. Results are more reliable if verified through these methods.
The procedure followed in drawing conclusion from the sample values are known as statistic inference or inferential statistics.
Consist of 2 aspects;
ESTIMATION OF PARAMETERS
HYPOTHESIS TESTING
A confidence interval gives an estimated range of values which is likely to include an unknown population parameter, the estimated range being calculated from a given set of sample data.
This document provides an overview of evidence-based orthodontics. It defines evidence-based orthodontics as integrating the best available research evidence with clinical expertise and patient values. The need for evidence-based orthodontics is that it allows practitioners to provide the currently best care available to patients. Evidence-based orthodontic practice differs from traditional practice by regularly accessing new evidence, identifying risk factors, and providing continuous, patient-centered, and efficient care. Systematic reviews are used to summarize research evidence in an unbiased manner to inform clinical decision making.
Clinical Questions types .
A Hierarchy of Preprocessed Evidence.
EBM definition and value.
Knowledge and Skills Necessary for Optimal Evidence-Based Practice.
Basic computer and internet knowledge for electronic searching of the literature
This document provides guidance on critically analyzing research articles. It begins with background on the rapidly expanding medical literature and challenges of keeping up. It then discusses the different types of studies and offers "cheat sheets" to systematically review articles. For cohort studies, it suggests assessing validity, results and applicability. Key points include checking for objective exposure determination and covariate balance. It provides similar guides for diagnostic tests, prognosis, treatment and meta-analyses. The overall goal is to review articles systematically and focus on methodological validity, clinically meaningful results and applicability to one's practice.
The critical appraisal process examines research to judge its validity and relevance. It involves summarizing key aspects of research articles like the introduction, methods, results and discussion sections. Important tools for appraisal include the PICO method to assess the research question, and CASP checklists tailored to different study designs. Proper appraisal helps identify clinically relevant papers and supports evidence-based decision making.
This document discusses the history and process of scientific peer review. It begins by outlining some of the earliest documented uses of peer review in the 9th century by Ishaq bin Ali Al-Rahawi and in the 18th century by the Royal Society of London. It then describes how peer review evolved in the early 1900s in scientific journals and was facilitated by the introduction of photocopiers. The document outlines different peer review systems and their advantages and disadvantages. It also discusses ways to improve peer review, including the roles of authors, editors, reviewers, and publishers. Overall, the document provides a high-level overview of the development and current state of scientific peer review.
This document provides an overview of quality in scientific research. It defines quality as meeting standards of scientific rigor, such as having a well-defined research question, transparent and reproducible methodology, and unbiased reporting of results. The document discusses research quality standards, validity, quantitative and qualitative research methods, and checklists for standardized research reporting. It also addresses challenges in promoting quality and characteristics of high-quality research.
This document summarizes the key aspects of evaluating clinical trials. In 3 sentences:
Clinical trials aim to determine if new treatments are safe and effective by testing them on people after promising laboratory and animal studies. Different types of clinical trials exist, from uncontrolled to randomized controlled trials, with RCTs being the gold standard as they randomly assign participants to interventions to reduce bias. Properly evaluating trials involves assessing their design, limitations, and results to determine the risk of bias and whether the trial's conclusions are valid and applicable to a specific patient.
The document discusses evidence based medicine (EBM), which uses clinical research and other evidence to guide medical decisions. It defines EBM and outlines its key principles, objectives, and steps. EBM aims to minimize errors and optimize care quality by integrating the best research evidence with clinical expertise and patient values and preferences. The document reviews the contents of EBM, the four steps to applying it including formulating questions and searching evidence, and the merits of EBM in improving patient care and reducing costs. Factors influencing the practice of EBM are also discussed.
Chapter 2
Study Designs
Learning Objectives
• List and define the components of a good
study design
• Compare and contrast observational and
experimental study designs
• Summarize the advantages and disadvantages
of alternative study designs
Learning Objectives
• Describe the key features of a randomized
controlled trial
• Identify the study designs used in public health
and medical studies
Study Designs
• Observational Studies
– Case-series study
– Cross-sectional (prevalence) survey
– Case-control study
– Cohort study
• Experimental Studies
– Randomized Controlled (Clinical) Trial
Inferences
• Observational studies – inferences limited to descriptions
and associations; with carefully designed analysis can
make stronger inferences (statistical adjustment)
• Experimental studies – cause and effect
In ALL studies – need careful definition of disease
(outcome) and exposure (risk factor)
Which Design is Best
• Depends on the study question
• What is current knowledge on topic
• How common is disease (and risk factors)
• How long would study take, what are costs
• Ethical issues
Case Report/Case Series
• Observational study
• Case report: Detailed report of specific
features of case
• Case series: Systematic review of common
features of a small number of cases
• Advantage: Cost-efficient
• Disadvantages: No comparison group, no
specific research question
Case-Series
• Simplest design – description of interesting
observations in a small number of individuals
• Usually case-series do not involve control patients
(i.e., patients free of disease)
• Usually lead to generation of hypotheses for more
formal testing
• Criticisms: not planned – no research hypotheses
Case-Series
• Gottleib (1981) studied 5 young homosexual
men with rare form of pneumonia and other
unusual infections
• Initial report was followed by more series (26
cases in NY and CA; “cluster” in southern CA;
34 cases among Haitians, etc.)
• Condition termed AIDS in 1982
Cross-Sectional Survey
• Observational study conducted at a point in
time
• Advantages: Cost-efficient, easy to implement,
ethical
• Disadvantages: No temporal information, non-
response bias
Cross-Sectional Survey
• Is there an association between diabetes and
cardiovascular disease (CVD)?
Patients
with
Diabetes
Patients without
Diabetes
Patients with
CVD
Prospective Cohort Study
• Observational study involving a group (cohort)
of individuals who meet inclusion criteria
followed prospectively in time for risk factor
and outcome information
• Advantages: Can assess temporal relationships
• Disadvantages: Need large numbers for rare
outcomes, confounding
Cohort Study
• Is there an association between hypertension and
cardiovascular disease?
CVD
Hypertension
No CVD
Cohort
CVD
No Hypertension
No CVD
Study Start Time
Cohort Studies
• Identify a group of individuals that meet
inclusion crit ...
Critical appraisal of a journal articleDrSahilKumar
This document provides guidance on critically appraising journal articles. It defines critical appraisal as systematically identifying the strengths and weaknesses of research to assess validity and usefulness. Key aspects to evaluate include relevance of the research question, appropriateness of study design, addressing biases, adherence to original protocol, statistical analyses, and conflicts of interest. Checklists like CASP, CONSORT, and STROBE provide frameworks to appraise study methodologies like randomized trials, systematic reviews, and observational studies. The goal of critical appraisal is for clinicians to identify high-quality evidence to inform clinical practice.
1) The document summarizes key aspects of evaluating clinical trials, including types of trials and potential biases.
2) Clinical trials aim to test interventions in a controlled manner to determine safety and effectiveness. Randomized controlled trials (RCTs) are considered the gold standard for limiting biases.
3) However, biases can still influence trials in many ways, such as through selection of participants, administration of interventions, measurement of outcomes, and reporting/publication of results. It is important to critically appraise trials to assess risk of biases.
Workshop Part 2: Publication Ethics for Biomedical Researchers (BioMed Centra...balaram_biomedcentral
The second presentation in the 2015 BioMed Central author workshop presented at institutions in Brazil.
In this segment, Dr. Maria Kowalczuk, Biology Editor, shares information on research ethics and publication ethics, drawing from her experience as a member of the BioMed Central Research Integrity Group.
This document outlines an agenda for a class on critically appraising medical literature. It begins with reviewing the health science research process and types of research studies. It then discusses what a critical appraisal is and how to appraise a research paper. Key questions to ask when appraising medical literature are presented. The document reviews levels of evidence and study types like randomized controlled trials, cohort studies, and case-control studies. It provides guidance on critically appraising diagnostic studies, intervention studies, and calculating p-values. An in-class appraisal activity is planned to conclude the session.
Interested in a tool to appraise all types of public health evidence?
Do you appraise public health evidence? Are you interested in a single tool that can appraise many different types of evidence and study designs? Join us for a webinar to learn about the MetaQAT.
This tool was developed by Public Health Ontario.
How can the MetaQAT help you?
Many different types of evidence and study designs may be used to answer a single public health question. The MetaQAT provides a single process that can be used to appraise these different types of evidence. This supports the use of evidence to formulate recommendations and develop public health actions.
The MetaQAT consists of a four domain appraisal framework that includes relevance, reliability, validity, and applicability. A suite of design-specific companion tools are included to provide further guidance to assess validity of common designs.
This webinar includes an overview of the MetaQAT by its developer, Dr. Laura Rosella, followed by a presentation from Dr. Catherine Bornbaum, who used the MetaQAT in conducting a systematic review.
To see the summary statement of this tool developed by NCCMT, click here: http://www.nccmt.ca/resources/search/243
The National Collaborating Centre for Methods and Tools is funded by the Public Health Agency of Canada and affiliated with McMaster University. The views expressed herein do not necessarily represent the views of the Public Health Agency of Canada.
NCCMT is one of six National Collaborating Centres (NCCs) for Public Health. The Centres promote and improve the use of scientific research and other knowledge to strengthen public health practices and policies in Canada.
This document outlines the key principles of evidence-based medicine (EBM). EBM uses clinical expertise and the best available research evidence to make decisions about patient care. It involves four main steps: formulating a clinical question based on a patient's situation, searching for the best evidence to answer the question, critically appraising the evidence for validity and usefulness, and applying the results to the patient. EBM aims to minimize errors and optimize quality in patient care by providing a rigorous framework for clinical decision making based on available research evidence. Factors that influence the practice of EBM include the large volume of available literature, difficulties synthesizing evidence and translating it to specific patients, and the increasing number of randomized controlled trials.
Sources of medical knowledge (1 october 2012)jgdaams
This document discusses various resources for finding scientific medical information, including their strengths and limitations. It covers searching the internet, peer-reviewed journals and articles, books, catalogs, bibliographic databases, and clinical practice guidelines. For journals and articles, it discusses assessing quality through metrics like the Journal Impact Factor as well as open access. When searching bibliographic databases, it notes that PubMed contains more records than MEDLINE alone. Overall, the document provides an overview of key sources for medical evidence and factors to consider when evaluating them.
This document discusses evidence-based medicine (EBM). It defines EBM as integrating the best available clinical research with individual expertise and patient values. EBM involves using a hierarchy of evidence, with randomized controlled trials considered the gold standard, to make informed healthcare decisions. Systematic reviews and meta-analyses also provide high-level evidence by comprehensively analyzing available studies. The key aspects of EBM are asking questions, acquiring evidence, appraising studies, applying evidence to individual cases, and assessing outcomes. EBM aims to optimize patient care through minimizing errors and reducing costs by ensuring treatment is based on the most valid and applicable research available.
The document discusses identifying bias in scientific studies. It states that good science minimizes bias through random sampling, minimizing measurement bias, and accounting for multiple factors. Bias can come from the language used, data reported, and source of the data. The scientific community engages in quality control like independent duplication of results and peer review to eliminate bias.
The document discusses identifying bias in scientific studies. It states that good science minimizes bias through random sampling, minimizing measurement bias, and having a large enough sample size. Bias can influence results and different scientists may find different solutions to the same problem. The scientific community engages in quality control like independent duplication of studies and peer review to eliminate bias. Results are more reliable if verified through these methods.
The procedure followed in drawing conclusion from the sample values are known as statistic inference or inferential statistics.
Consist of 2 aspects;
ESTIMATION OF PARAMETERS
HYPOTHESIS TESTING
A confidence interval gives an estimated range of values which is likely to include an unknown population parameter, the estimated range being calculated from a given set of sample data.
learning objectives
Introduction
History Of Water Fluoridation
How Does Fluoride Act In Dental Caries Prevention?
Goals Of F Administration
Fluoride Administration
Appropriate Levels Of Fluoride in Drinking Water
Methods of water fluoridation
--------------------------------------------------------------------
Efficacy Of topical fluorides
Range Of therapeutic fluoride concentrations used to prevent caries
Recommended doses
The document provides an introduction to epidemiology, defining it as the study of health-related states and events in populations and the application of this study to control health problems. It describes the purposes and uses of epidemiology, the 5Ws (who, what, when, where, why), categories of descriptive and analytic epidemiology, and levels of disease occurrence such as endemic, epidemic, sporadic, and pandemic. The document aims to outline key concepts in epidemiology for learning objectives.
This document discusses dental public health. It begins by defining dental public health as the science and art of preventing oral diseases, promoting oral health, and improving quality of life through organized community efforts. It then discusses some of the key tools in dental public health, including epidemiology, biostatistics, social sciences, principles of administration, and preventive dentistry. It also outlines the typical procedural steps in dental public health projects, including surveys, analysis, program planning, implementation, financing, and evaluation. Finally, it notes that criteria are important for defining what constitutes a public health problem to allow for proper management.
This document provides an introduction to epidemiology. It defines epidemiology as the study of health-related states and events in populations and applying this to control health problems. Epidemiology is used to assess community health, identify new diseases, monitor existing diseases, and evaluate control measures. The five Ws of epidemiology are the clinical aspects (what), descriptive epidemiology (who, where, when), and analytic epidemiology (why, how). Descriptive studies overview patterns of occurrence while analytic studies assess disease determinants. Diseases are also classified by their levels of occurrence as endemic, epidemic, sporadic, or pandemic based on how many people are affected and whether the disease is a new outbreak or constant presence.
This document discusses descriptive statistics concepts including range, frequency distribution, normal distribution, and standard deviation. It defines range as the difference between the smallest and largest values. Frequency distribution provides the number of occurrences of values within intervals. The normal distribution is widely used and defined by the mean and standard deviation. Standard deviation measures how far values deviate from the mean on average. It uses examples to illustrate these statistical concepts.
This document discusses key concepts in descriptive statistics including measures of dispersion like range and standard deviation, frequency distributions, the normal distribution, and the empirical rule. It defines range as the difference between the largest and smallest values. Frequency distributions provide the number of occurrences of values using tables or graphs. The normal distribution is widely used and defined by the mean and standard deviation. Standard deviation measures how far values deviate from the mean. The empirical rule states that 68%, 95%, and 99.7% of values in a normal distribution fall within 1, 2, and 3 standard deviations of the mean, respectively.
This document discusses methods for presenting data, including tabulation, charts, diagrams, and graphs. Tabulation involves arranging statistical data systematically into rows and columns. Charts and diagrams are also covered as visual methods for presenting and comparing quantitative data. The document appears to be part of a presentation on biostatistics that covers essential techniques for organizing and displaying different types of data.
This document discusses descriptive statistics. It defines descriptive statistics as summarizing and organizing characteristics of a data set. Descriptive statistics are useful for describing large data sets with measures of central tendency like mean, median, and mode, and measures of dispersion. Inferential statistics makes predictions about a population from a sample. The key difference between descriptive and inferential statistics is that descriptive statistics describes data, while inferential statistics makes generalizations from samples to populations. Measures of central tendency describe the central or typical values in a data set, while measures of dispersion describe how spread out the data values are.
This document discusses the different levels of disease prevention:
1) Primordial prevention aims to prevent risk factors from developing in a population through education and policies around nutrition, smoking, physical activity, and lifestyle changes.
2) Primary prevention removes the possibility of disease through actions like vaccination taken before disease onset, with approaches targeting whole populations or high-risk groups.
3) Secondary prevention stops disease at early stages through early detection (like dental screenings) and treatment to prevent progression and complications.
4) Tertiary prevention focuses on reducing impairments and disabilities in advanced disease through rehabilitation, exercises, reconstructive surgery, and prosthetics to promote adjustment to conditions.
The document discusses research study designs used in epidemiology, including descriptive designs like case reports and cross-sectional studies which observe characteristics at a single point in time, as well as longitudinal studies which observe the same population over multiple time periods; it also covers analytical designs like case-control and cohort studies which analyze determinants of diseases. Research design aims to objectively, precisely, reliably, and validly answer a research question by collecting and analyzing relevant data.
Exercise is a confounding variable in this study. It is associated with both occupation (coal miners exercise less than farm workers) and lung capacity, but it is not on the causal pathway between occupation and lung capacity.
This document provides an overview of biostatistics and different types of variables and data. It defines biostatistics as the application of statistical methods to biological and health data. It discusses qualitative and quantitative variables and different types of each. Qualitative variables are categorical and include binary, nominal, and ordinal variables. Quantitative variables are numerical and include continuous and discrete data. The document also outlines different types of data: nominal data involves names or labels without order; ordinal data adds order; interval data involves equal distances on a scale; and ratio data has a true zero point and ratios can be calculated.
This particular slides consist of- what is Pneumothorax,what are it's causes and it's effect on body, risk factors, symptoms,complications, diagnosis and role of physiotherapy in it.
This slide is very helpful for physiotherapy students and also for other medical and healthcare students.
Here is a summary of Pneumothorax:
Pneumothorax, also known as a collapsed lung, is a condition that occurs when air leaks into the space between the lung and chest wall. This air buildup puts pressure on the lung, preventing it from expanding fully when you breathe. A pneumothorax can cause a complete or partial collapse of the lung.
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Microstomia, characterized by an abnormally small oral aperture, presents significant challenges in prosthodontic treatment, including limited access for examination, difficulties in impression making, and challenges with prosthesis insertion and removal. To manage these issues, customized impression techniques using sectional trays and elastomeric materials are employed. Prostheses may be designed in segments or with flexible materials to facilitate handling. Minimally invasive procedures and the use of digital technologies can enhance patient comfort. Education and training for patients on prosthesis care and maintenance are crucial for compliance. Regular follow-up and a multidisciplinary approach, involving collaboration with other specialists, ensure comprehensive care and improved quality of life for microstomia patients.
CHAPTER 1 SEMESTER V COMMUNICATION TECHNIQUES FOR CHILDREN.pdfSachin Sharma
Here are some key objectives of communication with children:
Build Trust and Security:
Establish a safe and supportive environment where children feel comfortable expressing themselves.
Encourage Expression:
Enable children to articulate their thoughts, feelings, and experiences.
Promote Emotional Understanding:
Help children identify and understand their own emotions and the emotions of others.
Enhance Listening Skills:
Develop children’s ability to listen attentively and respond appropriately.
Foster Positive Relationships:
Strengthen the bond between children and caregivers, peers, and other adults.
Support Learning and Development:
Aid cognitive and language development through engaging and meaningful conversations.
Teach Social Skills:
Encourage polite, respectful, and empathetic interactions with others.
Resolve Conflicts:
Provide tools and guidance for children to handle disagreements constructively.
Encourage Independence:
Support children in making decisions and solving problems on their own.
Provide Reassurance and Comfort:
Offer comfort and understanding during times of distress or uncertainty.
Reinforce Positive Behavior:
Acknowledge and encourage positive actions and behaviors.
Guide and Educate:
Offer clear instructions and explanations to help children understand expectations and learn new concepts.
By focusing on these objectives, communication with children can be both effective and nurturing, supporting their overall growth and well-being.
This particular slides consist of- what is hypotension,what are it's causes and it's effect on body, risk factors, symptoms,complications, diagnosis and role of physiotherapy in it.
This slide is very helpful for physiotherapy students and also for other medical and healthcare students.
Here is the summary of hypotension:
Hypotension, or low blood pressure, is when the pressure of blood circulating in the body is lower than normal or expected. It's only a problem if it negatively impacts the body and causes symptoms. Normal blood pressure is usually between 90/60 mmHg and 120/80 mmHg, but pressures below 90/60 are generally considered hypotensive.
The facial nerve, also known as cranial nerve VII, is one of the 12 cranial nerves originating from the brain. It's a mixed nerve, meaning it contains both sensory and motor fibres, and it plays a crucial role in controlling various facial muscles, as well as conveying sensory information from the taste buds on the anterior two-thirds of the tongue.
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2. • EBD is sequential, systematic process of addressing a
clinical or community relevant problems.
• EBD components are;
–Clinical expertise
–Patient’s preferences & values
–Highest level of evidence
3. 1. Identification of a Clinical Problem
2. Search for Evidence
3. Making Sense of Evidence
4. Act on Evidence
4. Identification of a Clinical Problem
–P = patient/ population/ problem (among_____?)
–I = Intervention / Exposure (does_______?)
–C= Comparison (versus_______?)
–O= Outcome (affect________?)
• Understand 2 Ts; Type of question & Type of
research desighn - PICOTT
5. • Q. Is ischlorhexadine varnish more effective than sodium
fluoride varnish in preventing root caries? (seeks
evidence of effectiveness of treatment) P I C O
• Q. Will chronic smokers experience delayed
osteointegration after implant placement? (seeks
evidence of ascertain causes or risk factors)
6. • Quality of evidence: Systematic review rather than
individual study for any type of question
• hierarchy of of research designs based on quality of
research design - Evidence Pyramid
7.
8. Step 2: Search for Evidence
1. Primary Evidence: Original Articles
2. Secodary Evidence: Studies of studies/ systematic
reviews
WHERE DO WE SEARCH FOR EVIDENCE?
9. WHERE DO WE SEARCH FOR EVIDENCE?
• Search engines: i-e google & google scholar. It search
the WEBSITES
• Meta- search engines: i-e SUM search & BIOME. It
search the SEARCH ENGINE & DATABASES.
• Databases: electronic bibliographic database is an
exhaustive resource of QUALITY RESEARCH, constantly
updated on all aspects of a scientific field.
10. Important general medical databases
1. Cochrane Library of Systematic Reviews ; by cochrane
approved reviewers
2. MEDLINE ;indexes over 5000 journals based on quality
review by US.National Library of Medicine.
• indexed journals are higher scientific quality as compared to non-
indexed journals
11. Important general medical databases
3. PubMed; is a freely available database, which contains
all the journals indexed by MEDLINE.
Developed by US National Library of Medicine &
National Center for Biotechnology Information.
4. EMBASE; important because of update on DRUGS /
PHARMACOLOGY
12. Step 3: Making Sense of Evidence
1. Important component to sense evidence are;
1. study quality( methodological quality including statistics)
2. Bias (systematic errors)
3. Internal Validity (validity)
4. External Validity (generalizability, applicability)
2. Recovered evidence should be appraised/ evaluate
3. Update new evidence & discard poor evidence
13. Step 4: Act On Evidence
• Good quality of evidence gives strength to
recommendation.
• Strength of recommendations due to quality evidence will
do more good than harm.
• EBD demands evidence on treatment plan depends must
have lowest possible risk of bias.
14. • The process of integrating science based intervention
which community preferences to improve the health of
populations.
• Define by
16. • Hence EBPH decision-making will include essentially all
the steps in EBD with emphasis on the public health
resources, the dynamics of the communities and
diversities of the socities on whom the interventions will
apply.
17.
18. • Peer-reviewed or refereed journals have an editorial
board of subject experts who review and evaluate
submitted articles before accepting them for publication.
• A journal may be a scholarly journal but not a peer-
reviewed journal.
19.
20. • When a manuscript is submitted to a journal, it is
assessed to see if it meets the criteria for submission. If it
does, the editorial team will select potential peer
reviewers within the field of research to peer-review the
manuscript and make recommendations.
21.
22. • Single-blind: the reviewers know the names of the
authors
• Double-blind: reviewers & authors both dont know
names of each other
• Open peer: authors know who the reviewers are, and
the reviewers know who the authors are.
23. • Transparent peer: the reviewers know the names of
the authors, but the authors do not know who reviewed
their manuscript unless the reviewer chooses to sign their
report. If the manuscript is accepted, the anonymous
reviewer reports are published alongside the article and
the authors’ response to the reviewer.