This document discusses evidence-based practice (EBP) in healthcare. It provides several definitions of EBP from different sources that emphasize systematically using the most current and valid research findings to inform clinical decisions. EBP integrates the best available research evidence, clinical expertise, and patient values. The document stresses that EBP is important for improving patient care by keeping practitioners up-to-date on the most effective treatments. It also notes that implementing EBP requires profiling research to identify effective treatments while considering clinical judgment in individual cases.