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Evaluation of medical
information quality
Jan Hrabal
Tomáš Pruša
Masaryk University, Brno
Why to evaluate?
Better decisions
Better health
Use of information
Theoretical framework
● Three-dimensional scheme by Anton Vedder
● Reliability ; (Functionality ; Significance)
● Content criteria & Pedigree criteria
What is quality of information?
● Derived from already existing methodics
● (HONcode: Principles, The DISCERN Instrument, MedlinePlus,
SPRY foundation, one review study (Risk & Dzenowagis, 2002),
book (Cullen, 2006)).
● Modified, extended, applicable in the Czech internet
environment
➔ Methodics for laymen
➔ Methodics for experts – modified and extended –
includes evaluation of research papers and reviews
Methodics for other than expert sources in
common online environment
CRITERIA OF FORM
● 1. Origin
– Is the originator of the information expert in the field?
– Is the author an original source of the information or
intermediary?
– Is the originator of the information health
organization?
Methodics for other than expert sources in
common online environment
CRITERIA OF FORM
● 2. Sponsorship
– Is a sponsor, owner or provider of the website
retrievable or deducible?
Methodics for other than expert sources in
common online environment
CRITERIA OF FORM
● 3. Purpose and intent
– Is it retrievable, in what purposes and intents did
the website develop and in what intents runs
now?
– Is the intent of the website to educate and provide
objective facts? (The intent of the website is not
to sell products or to offer services.)
Methodics for other than expert sources in
common online environment
CRITERIA OF FORM
● 4. Currency and date
– < 10 years
Methodics for other than expert sources in
common online environment
CRITERIA OF FORM
● 5. Citation and links
– Are there any citation and links on expert sources
present?
Methodics for other than expert sources in
common online environment
CONTENT CRITERIA
● 6. Accuracy and completeness
– Does the information refer to effect of the product (drug) or
service (medical help)?
– Does the information refer to explanation or description of a
disease or undesirable condition?
– Does the information refer to healthy nutrition or food
ingredient?
– Does the information refer to healthy lifestyle or circumstances
causing health?
Methodics for other than expert sources in
common online environment
CONTENT CRITERIA
● 7. Clarity
– Is the text clear and easily readable?
Methodics for expert sources in online
environment
● Indicators same, little modified, but instead of
indicator of 'clarity' is indicator of 'accuracy and
formulation'
● Includes evaluation of reviews and
experimental parts
Methodics for expert sources in online
environment
IF IT IS LITERATURE REVIEW...IF IT IS LITERATURE REVIEW...
● Collection of information
Is it described how the selection of information sources was
made?
Does it include recent information sources in the subject?
Are the studies that support results of the paper but also
disprove the results taken into account?
Do the stated information sources have a maximum position in
the hierarchy of evidence within the context of use and goals of
the paper?
Methodics for expert sources in online
environment
IF IT IS LITERATURE REVIEW...IF IT IS LITERATURE REVIEW...
● Interpretation
Did the study take into account type of studied subjects, the size
of studied groups and the length of the experiment in the original
publication?
Haven't the interpretation for human health been created on the
basis of animal models?
Was the correlation and causality distinguished?
Have the both positive and negative effects been taken into
account?
Methodics for expert sources in online
environment
IF AN EXPERIMENT IS A PART...IF AN EXPERIMENT IS A PART...
● Groups studied
Are the characteristics of subjects described?
Is it described how the subjects were chosen and how
many were excluded?
Has the randomization been done if the study design
usually requires it?
Has the blinding been done if the study design usually
requires it?
Was the sample large enough in the context of the study?
Was the risk of selection bias reduced?
Methodics for expert sources in online
environment
IF AN EXPERIMENT IS A PART...IF AN EXPERIMENT IS A PART...
● Observation and intervention
Is the methodics of a study described enough?
Are the specifics of exposure described?
Was the observation / intervention carried out systematically in accordance with
the guidelines of the field and according to standard protocols?
In case of instruments and devices use, are they sufficiently described (producer,
type, batch), and is the limit of detection and limit of setting defined?
Were suitable methods for measuring exposure and outcome assessment or
outcome of the intervention chosen?
As part of the assessment pharmacotherapy or impact assessment of nutritional
supplements and lifestyle determinant, was it compared with placebo / standard
established treatment / or otherwise defined control groups?
Were the confounding factors in different groups defined and was the risk of their
occurrence reduced?
Methodics for expert sources in online
environment
IF AN EXPERIMENT IS A PART...IF AN EXPERIMENT IS A PART...
● Results
Are the methods of evaluation described (statistical tests etc.)?
Was the appropriate method for the statistical analysis of data used?
Is the effect size described enough? What is the rate?
– Experimental event rate (EER), control event rate (CER), relative risk
(RR), absolutive reduction risk (ARR), relative reduction risk (RRR),
number needed to treat (NNT).
What is the power of the study? Was the difference between intervention and
control group expressed?
How precise was the effect size? Was the confidence interval (CI)
expressed?
Were the appropriate methods for confounding factors assessment used?
If study design (case-control studies) needs it, was the odds ratio calculated?
Methodics for expert sources in online
environment
IF AN EXPERIMENT IS A PART...IF AN EXPERIMENT IS A PART...
● Data interpretation
Was the correlation and regression distinguished and were the
assumptions about causality expressed?
Was the null and alternative hypothesis for the statistical evaluation
defined?
Were the side effects stated?
Was the study conducted according to original protocol?
– Did the study not end sooner or later than it was originally planned?
– Were the patients who withdraw study or who did not comply the
treatment included into the results? Helpful term could be “intention-to-
treat.” Was the analyze of activity performed? Were the patients
analyzed in groups, in which they were divided?
Was the data interpreted correctly?
Limitations of expert methodics
● Is general, not suitable for specific topics or
health disciplines
● Not for diagnostic or screening tests
● Not for some types of qualitative studies
● Needs modification for evaluating studies of
alternative therapies
Jan Hrabal
Division of Information and Library Studies, Masaryk University
h.hrabal@gmail.com
Tomáš Pruša
Research Centre for Toxis Compounds in the Environment, Masaryk
University

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Jan Hrabal: Evaluation of medical information quality #bcs2015

  • 1. Evaluation of medical information quality Jan Hrabal Tomáš Pruša Masaryk University, Brno
  • 2. Why to evaluate? Better decisions Better health Use of information
  • 3. Theoretical framework ● Three-dimensional scheme by Anton Vedder ● Reliability ; (Functionality ; Significance) ● Content criteria & Pedigree criteria What is quality of information?
  • 4. ● Derived from already existing methodics ● (HONcode: Principles, The DISCERN Instrument, MedlinePlus, SPRY foundation, one review study (Risk & Dzenowagis, 2002), book (Cullen, 2006)). ● Modified, extended, applicable in the Czech internet environment ➔ Methodics for laymen ➔ Methodics for experts – modified and extended – includes evaluation of research papers and reviews
  • 5. Methodics for other than expert sources in common online environment CRITERIA OF FORM ● 1. Origin – Is the originator of the information expert in the field? – Is the author an original source of the information or intermediary? – Is the originator of the information health organization?
  • 6. Methodics for other than expert sources in common online environment CRITERIA OF FORM ● 2. Sponsorship – Is a sponsor, owner or provider of the website retrievable or deducible?
  • 7. Methodics for other than expert sources in common online environment CRITERIA OF FORM ● 3. Purpose and intent – Is it retrievable, in what purposes and intents did the website develop and in what intents runs now? – Is the intent of the website to educate and provide objective facts? (The intent of the website is not to sell products or to offer services.)
  • 8. Methodics for other than expert sources in common online environment CRITERIA OF FORM ● 4. Currency and date – < 10 years
  • 9. Methodics for other than expert sources in common online environment CRITERIA OF FORM ● 5. Citation and links – Are there any citation and links on expert sources present?
  • 10. Methodics for other than expert sources in common online environment CONTENT CRITERIA ● 6. Accuracy and completeness – Does the information refer to effect of the product (drug) or service (medical help)? – Does the information refer to explanation or description of a disease or undesirable condition? – Does the information refer to healthy nutrition or food ingredient? – Does the information refer to healthy lifestyle or circumstances causing health?
  • 11. Methodics for other than expert sources in common online environment CONTENT CRITERIA ● 7. Clarity – Is the text clear and easily readable?
  • 12. Methodics for expert sources in online environment ● Indicators same, little modified, but instead of indicator of 'clarity' is indicator of 'accuracy and formulation' ● Includes evaluation of reviews and experimental parts
  • 13. Methodics for expert sources in online environment IF IT IS LITERATURE REVIEW...IF IT IS LITERATURE REVIEW... ● Collection of information Is it described how the selection of information sources was made? Does it include recent information sources in the subject? Are the studies that support results of the paper but also disprove the results taken into account? Do the stated information sources have a maximum position in the hierarchy of evidence within the context of use and goals of the paper?
  • 14. Methodics for expert sources in online environment IF IT IS LITERATURE REVIEW...IF IT IS LITERATURE REVIEW... ● Interpretation Did the study take into account type of studied subjects, the size of studied groups and the length of the experiment in the original publication? Haven't the interpretation for human health been created on the basis of animal models? Was the correlation and causality distinguished? Have the both positive and negative effects been taken into account?
  • 15. Methodics for expert sources in online environment IF AN EXPERIMENT IS A PART...IF AN EXPERIMENT IS A PART... ● Groups studied Are the characteristics of subjects described? Is it described how the subjects were chosen and how many were excluded? Has the randomization been done if the study design usually requires it? Has the blinding been done if the study design usually requires it? Was the sample large enough in the context of the study? Was the risk of selection bias reduced?
  • 16. Methodics for expert sources in online environment IF AN EXPERIMENT IS A PART...IF AN EXPERIMENT IS A PART... ● Observation and intervention Is the methodics of a study described enough? Are the specifics of exposure described? Was the observation / intervention carried out systematically in accordance with the guidelines of the field and according to standard protocols? In case of instruments and devices use, are they sufficiently described (producer, type, batch), and is the limit of detection and limit of setting defined? Were suitable methods for measuring exposure and outcome assessment or outcome of the intervention chosen? As part of the assessment pharmacotherapy or impact assessment of nutritional supplements and lifestyle determinant, was it compared with placebo / standard established treatment / or otherwise defined control groups? Were the confounding factors in different groups defined and was the risk of their occurrence reduced?
  • 17. Methodics for expert sources in online environment IF AN EXPERIMENT IS A PART...IF AN EXPERIMENT IS A PART... ● Results Are the methods of evaluation described (statistical tests etc.)? Was the appropriate method for the statistical analysis of data used? Is the effect size described enough? What is the rate? – Experimental event rate (EER), control event rate (CER), relative risk (RR), absolutive reduction risk (ARR), relative reduction risk (RRR), number needed to treat (NNT). What is the power of the study? Was the difference between intervention and control group expressed? How precise was the effect size? Was the confidence interval (CI) expressed? Were the appropriate methods for confounding factors assessment used? If study design (case-control studies) needs it, was the odds ratio calculated?
  • 18. Methodics for expert sources in online environment IF AN EXPERIMENT IS A PART...IF AN EXPERIMENT IS A PART... ● Data interpretation Was the correlation and regression distinguished and were the assumptions about causality expressed? Was the null and alternative hypothesis for the statistical evaluation defined? Were the side effects stated? Was the study conducted according to original protocol? – Did the study not end sooner or later than it was originally planned? – Were the patients who withdraw study or who did not comply the treatment included into the results? Helpful term could be “intention-to- treat.” Was the analyze of activity performed? Were the patients analyzed in groups, in which they were divided? Was the data interpreted correctly?
  • 19. Limitations of expert methodics ● Is general, not suitable for specific topics or health disciplines ● Not for diagnostic or screening tests ● Not for some types of qualitative studies ● Needs modification for evaluating studies of alternative therapies
  • 20. Jan Hrabal Division of Information and Library Studies, Masaryk University h.hrabal@gmail.com Tomáš Pruša Research Centre for Toxis Compounds in the Environment, Masaryk University