This document discusses Entamoeba coli, a non-pathogenic intestinal parasite commonly found in humans. It describes E. coli's life cycle between a trophozoite stage inside the intestine and a cyst stage passed in feces. Transmission occurs worldwide via the fecal-oral route through contaminated food or water. While usually harmless, large populations of E. coli can cause minor digestive issues. Diagnosis involves examining stool samples under a microscope for cysts or trophozoites. Treatment is not usually needed, but improved hygiene can reduce transmission.