The document discusses the efficiency of muscle work. It defines efficiency as the ratio of mechanical work output to total metabolic cost, which can be calculated from oxygen consumption. The efficiency of human muscle has been measured at 18-26% for rowing and cycling. The quadriceps muscle, a large thigh muscle, has an efficiency that has also been measured. Maintaining good muscle activity and using electrical muscle stimulators can help target the communication system between the brain and muscles. The quadriceps contributions to energy generation and dissipation at the knee joint were also examined during different phases of running. Maintaining mechanical efficiency is important for exercise and knee rehabilitation.