Alcohol consumption has numerous effects on the body. It is a powerful psychoactive drug that impacts multiple organs and systems. The amount and circumstances of drinking determine the level and duration of intoxication. Heavy drinking over long periods of time can lead to serious liver diseases like cirrhosis in around 20% of heavy drinkers and alcoholic hepatitis in approximately 35% of heavy drinkers, which can cause inflammation and progressive damage to the liver. Alcohol also negatively impacts brain function causing issues like impaired coordination, vision and memory, as well as daily life through potential abuse and unemployment.
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This presentation is all about Alcoholism-sign, effects, symptoms and treatment..
Special thanks to Mayo clinic organization for providing information for this presentation...
thank you.. and enjoy...
"keep moving forward"
Uploader's Note:
The following Text, information and materials used in this presentation do not own by the uploader.
This presentation is all about Alcoholism-sign, effects, symptoms and treatment..
Special thanks to Mayo clinic organization for providing information for this presentation...
thank you.. and enjoy...
"keep moving forward"
This Slide talks about alcohol, the good sides, the bad sides and understanding what the addicts are going through and how they can cure their addiction is a simple and easy to understand format
This Slide talks about alcohol, the good sides, the bad sides and understanding what the addicts are going through and how they can cure their addiction is a simple and easy to understand format
Alcoholism is a hazard to the society and has a number of medico-legal implications. This presentation is shared with the hope to enlighten the educated masses to abstain from alcohol or consume it in moderate amounts. The impact of alcoholism( acute and chronic) on the human body are so tremendous that it should also serve as a warning for the younger generations as well.
Anesthetic consideration in smokers,alcoholics and addictsAftab Hussain
Anaesthetic consideration in smokers alcoholic and drug addicts. As an anaesthesiologist we must be aware with the problems associated with their management and interaction with anaesthetics.
EVERYTHING YOU NEED TO KNOW ABOUT ALCOHOLAKASH GOEL
What exactly is alcohol?
> Alcoholics aren't the only ones who have a drinking issue. Alcohol use problems come in a variety of degrees or levels, ranging from minor to severe. To have a drinking issue, you don't have to drink every day or even on a regular basis.
Alcohol (ethanol, EtOH) has pleiotropic actions and induces a number of acute and long-term effects due to direct actions on alcohol targets, and effects of alcohol metabolites and metabolism
Alcohol is by far the most frequently used and abused addictive drug, and therefore a detailed understanding of the molecular mechanisms of alcohol actions is important to human health and well-being
1. Local actions:-
Ethanol is a mild rubefacient (agent Produces redness of skin)
and counterirritant when rubbed on
the skin. By evaporation it produces cooling.
Applied to delicate skin (scrotum) or mucous membranes it produces irritation and burning sensation.
Concentrated alcohol (spirit) should not be applied in the mouth, nose, etc. Injected s.c. it causes intense pain, inflammation and necrosis.
Applied to the surface, alcohol is an astringent— precipitates surface proteins and hardens the skin, and antiseptic property.
Alcohol does not
kill bacterial spores
Alcohol affects the entire body in an adverse manner, and to keep its functions at optimal health, it must be able to fight off diseases and illnesses of all type. Therefore, it is important to understand the impact of alcohol on the body’s immune system and start to take measures to prevent that. Treating the alcohol dependency or addiction should be the first step for people with this condition so that they are able to live a healthier life.
It is a common knowledge today that alcohol abuse is injurious to health and not just the physical health but the mental health of the person as well. But in this article, the focus is on understanding just how much damage is caused by alcohol addiction to the physical health of the person. To have a broad view of the subject, the effects of alcohol use can be divided into two types, as per Rehab Center in Mumbai.
This slides present to you some facts you must keep to mind about alcohol poisoning. Don't just laugh it off. People have lost loved ones because of not taking appropriate actions. Read this and share it with friends. You might be saving a soul
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
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Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
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2. Effects of alcohol onthebody The effects of alcohol on the body are numerous and diverse. Alcohol, specifically ethanol, is a powerful psychoactive drug with a level of side effects. The amount and circumstances of consumption play an important role in determining the duration of intoxication, for example, consuming alcohol after a big meal is less likely to produce visible signs of intoxication with the stomachvacío.1 Hydration also plays a role, especially in determining the length of hangovers.
3. harmful effects of alcohol on the brain The difficulty in walking, blurred vision, slurred speech, slowed reactions,impaired memory: Clearly, alcohol affects the brain.
4. Alcohol in everydaylife Alcohol damages your body inside, but also interferes with daily life , causing abuse to family, friends, unemployment.
5. Effects of alcohol on the skin Alcoholic beverages dehydrate us and, therefore, undermine the vital nutrients of the skin. Alcohol reduces the level of vitamin A in our body. This vitamin isresponsible for the regeneration of skin cells. Also affects the collagen fibers.
6. ALCoholiccirrhosis More severe liver disease, and certainly better known, alcohol isrelated to alcoholic cirrhosis, which occurs when the normal liver tissue is replaced by scar tissue. Approximately 20% of people who abuse drink suffer from cirrhosis.
7. ALCoholic hepatitis Approximately 35 percent of heavy drinkers suffer from alcoholic hepatitis, or liver inflammation. Moderate alcoholic hepatitis can last years and cause progressive liver damage, while the most severe alcoholic hepatitis may occur suddenly or after a session of heavy use, and possibly lead to complications that threaten the life of the person.
8. Alcohol causes the following symptoms Escuchar. Symptoms of alcoholic hepatitis include nausea, fever, jaundice, loss of appetite and vomiting.Alcohol also conveys to use other drugs.
