Lifestyle Modification For The Prevention of Heart DiseaseAdarsha Neupane
Here's a Presentation made by GROUP C on Lifestyle Modification For The Prevention of Heart Disease. This slide was created for Problem Based Learning (PBL) wrap up session Held At Kathmandu University- Birat Medical College Teaching Hospital (BMCTH).
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Lifestyle Modification For The Prevention of Heart DiseaseAdarsha Neupane
Here's a Presentation made by GROUP C on Lifestyle Modification For The Prevention of Heart Disease. This slide was created for Problem Based Learning (PBL) wrap up session Held At Kathmandu University- Birat Medical College Teaching Hospital (BMCTH).
feel free to Download and share this slide. You can leave comments for further improvement on other presentations. Thankyou. Cheers!
Diabetes is the most common lifestyle disorder in today's time. It need lifestyle modification. As experts suggests there is no cure for diabetes, but balanced diet and regular activity will help in managing the condition.
Diabetes is the most common lifestyle disorder in today's time. It need lifestyle modification. As experts suggests there is no cure for diabetes, but balanced diet and regular activity will help in managing the condition.
Lifestyle Modification For The Prevention of Heart DiseaseAdarsha Neupane
Here's a Presentation made by GROUP C on Lifestyle Modification For The Prevention of Heart Disease. This slide was created for Problem Based Learning (PBL) wrap up session Held At Kathmandu University- Birat Medical College Teaching Hospital (BMCTH).
feel free to Download and share this slide. You can leave comments for further improvement on other presentations. Thankyou. Cheers!
Lifestyle Modification For The Prevention of Heart DiseaseAdarsha Neupane
Here's a Presentation made by GROUP C on Lifestyle Modification For The Prevention of Heart Disease. This slide was created for Problem Based Learning (PBL) wrap up session Held At Kathmandu University- Birat Medical College Teaching Hospital (BMCTH).
feel free to Download and share this slide. You can leave comments for further improvement on other presentations. Thankyou. Cheers!
Diabetes is the most common lifestyle disorder in today's time. It need lifestyle modification. As experts suggests there is no cure for diabetes, but balanced diet and regular activity will help in managing the condition.
Diabetes is the most common lifestyle disorder in today's time. It need lifestyle modification. As experts suggests there is no cure for diabetes, but balanced diet and regular activity will help in managing the condition.
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Factory Supply Best Quality Pmk Oil CAS 28578–16–7 PMK Powder in Stockrebeccabio
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New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
2. Disclaimer
“The information, including but not limited to,
text, graphics, images and other material
contained in this presentation are for
informational purposes only.
Interventions mentioned here are mere adjunct
to the mainline treatment and not to replace it,
without professional medical advice.”
2
3. The Secret Of Good Health (आरोग्य हेतव)
नित्यं नहताहारनवहारसेवी समीक्ष्यकारी
नवषयेष्वसक्त:।
दाता सम: सत्यपर: क्षमावािाप्तोपसेवी च
भवत्यरोग:॥
Ashtanga Hridayam. (Vagbhata, 6th century
AD)
He, who indulges daily in healthy foods and activities,
who discriminates the good and bad of everything and
then acts wisely,
who is not attached too much to the objects of the senses,
Who, develops the habit of charity,
of considering all as equal, of truthfulness, of pardoning and
keeping company of good persons only, becomes free from
all diseases. 3
5. WHYSHOULD WE PREVENTDIABETES?
To reduce human suffering
Improve Quality of Life of
individuals
Reduce the number of
hospitalization
To reduce human suffering
Reduce mortality from diabetes
Prevent Sudden cardiac death 5
7. Urban – Rural Effect
•There is positive association between
Urbanisation & higher prevalence of
Type 2 Diabetes
•Population density and GDP are the
main determinant of diabetes
•Globalisation is playing an important
role in the rise of T2D worldwide
•Epidemiological and nutritional
transition
•Westernisation of the diet
7
8. Diet
Replace refined carbohydrates
with wholegrain foods & nuts
Low Glycemic Index food
Eat less salt
Drink plenty of water
Eat less red and processed
meat
Eat more fruit and veg
Choose healthier fats
Cut down on added sugar
Consume more amount of fiber
Drink alcohol sensibly
Increase intake of vegetables
Other foods high in dietary fiber.
No Junk food
Go Organic: Detoxify, Helps to
shed weight naturally &
Rejuvenate body
8
9. Junk food & Diabetes
•Highly calorific
•Nutritionally poor
•Low in fiber
•High in fat, sugar and salt
•May include additives such as Monosodium Glutamate
(MSG)
•May contain trans fats
•Often contain processed meats
•Can have addictive properties
•Research indicates that fast food promotes Insulin
resistance, which can lead to type 2 diabetes, as well as
weight gain 9
10. Meal Timings
•Regular & Fixed Meal timing helps with blood sugar
regulation
•Meal timings help regulate your internal clock
•Better glycemic control
•Better eating control
•Better energy levels
•Better biological balance for the body
•Have breakfast within an hour and half of waking up.
•Eat a meal every 4 to 5 hours after that.
•Have a snack between meals if you get hungry.
• Dinner ideally before sunset or 2 to 3 hrs before sleep 10
11. Exercise & Diabetes Mellitus
•The best time to exercise is one to
three hours after eating, when your
blood sugar level is likely to be higher
•Activities like brisk walk for 40 min
•Cycling
•Skipping , Dancing, Running ,
Swimming
•Push-ups, Lunges, and Squats
•Aerobic exercises like walking,
running, hiking, swimming, skiing,
and dancing are all
considered isotonic exercise. 11
13. WEIGHT REDUCTION
Weight reduction as little as 5% to
10% of body weight in
overweight people may
fundamentally lower
cardiovascular risk.
For most patients, a normal
weight reduction of 10 kg can
helps in reduction of insulin
requirement, 13
14. YOGA
Enhance the body Immune System
Reduces Stress, reducing Glucagon
Increases Blood flow & slow the heart
rate
Reduces the feeling of Depression, ,
Anxiety, Anger & Confusion
Increases Energy level
Eg. Bhujangasan, Uttanasan,
Trikonasan, Halasan, Salabhasan,
Dhanurasan, Sarvangasan &
Matsyasana 14
18. Pollution
•Air pollution is a novel risk factor
for insulin resistance and
occurrence of type 2 diabetes
•Air pollutants (e.g., PM and
NO2) are associated with higher
odds of diabetes.
•Air pollution is associated with
dysregulation of Glucose
metabolism.
18
19. Stress Management
• Perform yoga/meditation.
• Perform deep breathing exercises
(avoid if hypertensive)
• Listen soothing music
• Visit place of worship.
• Share your problems with your
family members or friends. 19
20. ♪ Listening to music relaxes blood vessels.
♪ In 2008, the journal Circulation reported on subjects who
listened to music that “evoked joy.”
♪ Their upper arm arteries expanded by an average of 26%.
♪ Listening to music reduces levels of stress hormones such as
cortisol.
♪ Music strengthens the immune system.
♪ Music can help improve mental balance.
♪ Sleep and eat better.
♪ Music reduces anxiety.
♪ Atharva - Vedic Richa For Diabetes | Ashwini Bhide Deshpande |
Times Music Spiritual
20
21. Improving Sleep
Some research suggests that
Not getting enough sleep
may impair insulin use and
increase the risk for obesity.
It is always wise to improve
sleep habits
21
22. Family relationships/social pressures.
High levels of family
conflict and family
distress are linked to
higher HbA1c’s in
kids/teens with diabetes.
Contentedness of life
Family support is crucial
Harmonious relationship
22
23. Prevention of Dementia due to Diabetes
•Type 2 diabetes mellitus (DM) has been shown to increase the risk for
•Cognitive decline
•Dementia, Alzheimer disease (AD) and
•Vascular dementia (VaD).
1 Eat a healthy diet rich in vitamin D, folate, and B6 and B12
2 Exercise regularly – both your body and mind,
3 Stay socially active and challenge yourself daily, and
4 Protect your head when playing sports.
•Is Alzheimer’s disease actually “Type 3 diabetes”?
• Increased risk of dementia in T2DM and obesity could be linked to chronic
hyperglycemia, peripheral insulin resistance, oxidative stress, accumulation of
advanced glycation end products, increased production of pro-inflammatory
cytokines, and/or cerebral microvascular disease
23
24. Dr. Dixit Sir Diet Plan
• Based on Known and proven
principle of ‘Intermittent Fasting’
• Fixed Meal timings, reduces
frequency of Insulin secretion
24
25. Socio-cultural Barriers For Diabetes
Control
Obesity is not considered negatively
Fad Food Culture has
caught up
Changing diet is very
difficult
No value given to physical exercise
No time for physical
exercise at work
Fatalism
25
26. ABCDEF of Diabetes Control
A- HbA1c Control to keep it at <7.0%
B- Blood pressure Control (<140/90mm Hg)
C- Cholesterol Control to keep your LDL below 100
mg/dL
D- Diet & Drug.
E- Exercise & Eye check up every 2 years thereafter
F- Foot Care on regular basis.
26
27. T
AKE HOME MESSAGES…
• Type 2 diabetes can be prevented
• Glycemic control
• Low GI diet with lots of GLV
• Blood pressure Control
• Exercise
• Stop Smoking
• Lifestyle interventions are effective in
prevention 27
29. References
• Textbook of Preventive & Social Medicine. K. Park, 23rd edition
• Text-book-of-public-health-and-community-medicine_compress.pdf
• Pollution and Diabetes - Diabetes Self-Management (diabetesselfmanagement.com)
• Air pollution and diabetes: it's time to get active! - The Lancet Planetary Health
• The Role of Exercise in Diabetes - PubMed (nih.gov)
• Effect of 6 Months of Meditation on Blood Sugar, Glycosylated Hemoglobin, and Insulin Levels in
Patients of Coronary Artery Disease
• https://pubmed.ncbi.nlm.nih.gov/31062329/
• https://adoretrust.org/eng/dr-jagannath-dixits-diabetes-reversal-and-effortless-weightloss-programme/
• https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2769828/
• https://www.cdc.gov/diabetes/managing/eat-well/meal-plan-method.html
• https://ayushnext.ayush.gov.in/detail/writeUps/what-is-a-healthy-lifestyle
• https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275761/
• Urbanization and prevalence of type 2 diabetes in Southern Asia: A systematic analysis (nih.gov) 29
What you eat determines how much sugar goes into your bloodstream and how quickly it gets there.
But when you eat is just as important.
If you eat the same amount of food (especially carbs) at the same time every day, that will help your blood sugar stay on an even keel.
When you feel like you’re starving, you may gobble up whatever’s handy, even if it’s not good for you. Or you may eat too much.