The document discusses designing e-learning and outlines six themes for 21st century learning: 1) personalize learning, 2) deliberately diversify, 3) put knowledge to work, 4) rethink roles, 5) continue to learn, and 6) connect with community. It emphasizes using technologies to support these themes, such as giving students personal choice in learning, supporting diversity, making learning authentic, having students and teachers create knowledge together, supporting ongoing learning and inquiry, and connecting with families and experts. The document advocates considering how to apply these themes when designing e-learning.