Cystinuria is an autosomal-recessive disease that affects the absorption of cystine, leading to its crystallization and stone formation in the kidneys. Symptoms include blood in urine, severe side pain, nausea, and recurring episodes when stones develop. Management strategies focus on increasing urine volume and pH, as well as utilizing procedures like lithotripsy.

1. By : AMEER AZEEZ
: ADIL SULAIMAN
Cystinuria
Kutaisi - ATSU
22-10-2015

2. Cystine : an amino acid

5. Cystinuria
Cystinuria is an autosomal-recessive disease. The genetic
defect impairs intestinal absorption and renal reabsorption
of cystine, causing elevated urinary levels of cystine and
subsequent crystallization and stone formation.

7. Pathophysiology

9. blood in the urine
severe pain in the side or the back (almost always o
n one side)
nausea and vomiting
pain near the groin, pelvis, or abdomen
Cystinuria is asymptomatic (causing no symptoms) when there are no stones.
However, the symptoms will recur each time stones form in the kidneys. The s
tones commonly return more than once.
Symptoms

10. Cystinuria : the solution
Increase solubility of cystine in urine
- increase the PH of urine
 decrease the concentration of cystine
- increase the urine volume
 change the cystine into cysteine

11. Extracorporeal shock wave lithotripsy

12. ureterolithotomy

13. Shukren
Thanks
Madloba