The most important application of nanotechnology is cryonics.
Cryonics – derived from the Greek language, kryos meaning icy cold. Cryonics is the low-temperature preservation of living things who/which can no longer be sustained by contemporary medicine, with the hope that healing and resuscitation may be possible in the future. Preserving to the point where molecular physical decay completely stops this state is known as cryonics suspension. The idea of cryonics was proposed by Robert Ettinger a Physics teacher after he read a book The Jameson Satellite by Neil R Jones in the year 1931. Later he published the books so called, The penultimate Triumph and The Prospects of Immortality in the years 1948 and 1962 respectively, which is a modern era of cryonics.
Robert Ettinger - ‘ originator and pioneer of cryonics’.
The word cryonics was proposed by Kerl Werner in 1965.
Later it was developed by CSM, CSC(not in use know),
CI, Alcor. In medicine, cryonics was once considered on the outer edge but is now moving closer to reality which means someone who died and was frozen last week may have a future again. Cryonics and nanotechnology form a useful pair.
Cryonics can transport a terminally ill patient to future medical technology.
this helps to understand the normal techniques related to biotechnology in a simple manner and provides you broad idea about the subject. A brief knowledge about the topic is presented in this presentation.
Tissue engineering and regenerative medicine Suman Nandy
Tissue engineering is the use of a combination of cells, engineering and materials methods, and suitable biochemical and physicochemical factors to improve or replace biological tissues. Tissue engineering involves the use of a scaffold for the formation of new viable tissue for a medical purpose.
Gene Therapy, Somatic cell gene therapy, germ line gene therapy, classical gene therapy, non-classical gene therapy, targets of gene therapy, barriers of gene therapy, ex vivo gene therapy, in vivo gene therapy, vectors for gene delivery, antisense therapy
Gene therapy is an experimental technique that uses genes to treat or prevent disease. The slides explain what is gene tharapy? Types of gene therapy. http://www.wesrch.com/
DNA cloning is a technique for reproducing DNA fragments.
It can be achieved by two different approaches:
▪ cell based
▪ using polymerase chain reaction (PCR).
a vector is required to carry the DNA fragment of interest into the host cell.
Artificial skin is a collagen scaffold that induces regeneration of skin in mammals such as humans. The term was used in the late 1970s and early 1980s to describe a new treatment for massive burns.
cryogenics is the production and behaviour of materials at very low temperatures. It is an effort to save lives by using temperatures so cold that a person beyond help by today's medicine can be preserved for decades or centuries until a future medical technology can restore that person to full health. Cryonics sounds like science fiction, but is based on modern science.
this helps to understand the normal techniques related to biotechnology in a simple manner and provides you broad idea about the subject. A brief knowledge about the topic is presented in this presentation.
Tissue engineering and regenerative medicine Suman Nandy
Tissue engineering is the use of a combination of cells, engineering and materials methods, and suitable biochemical and physicochemical factors to improve or replace biological tissues. Tissue engineering involves the use of a scaffold for the formation of new viable tissue for a medical purpose.
Gene Therapy, Somatic cell gene therapy, germ line gene therapy, classical gene therapy, non-classical gene therapy, targets of gene therapy, barriers of gene therapy, ex vivo gene therapy, in vivo gene therapy, vectors for gene delivery, antisense therapy
Gene therapy is an experimental technique that uses genes to treat or prevent disease. The slides explain what is gene tharapy? Types of gene therapy. http://www.wesrch.com/
DNA cloning is a technique for reproducing DNA fragments.
It can be achieved by two different approaches:
▪ cell based
▪ using polymerase chain reaction (PCR).
a vector is required to carry the DNA fragment of interest into the host cell.
Artificial skin is a collagen scaffold that induces regeneration of skin in mammals such as humans. The term was used in the late 1970s and early 1980s to describe a new treatment for massive burns.
cryogenics is the production and behaviour of materials at very low temperatures. It is an effort to save lives by using temperatures so cold that a person beyond help by today's medicine can be preserved for decades or centuries until a future medical technology can restore that person to full health. Cryonics sounds like science fiction, but is based on modern science.
Osiriscryonics believes that the future is surely going to evolve in the field of nanotechnology to make revival possible someday. With this belief on future, human preservation after death is encouraged by Cryobiologists.
PRINCIPLES OF CRYOSURGERY
Cryosurgery (cryotherapy) is the application of extreme cold to destroy abnormal or diseased tissue.
The term comes from the Greek words cryo ("icy cold") and surgery meaning "hand work" or "handiwork".
Cryosurgery has been historically used to treat several diseases and disorders, especially variety of benign and malignant skin conditions.
Mechanism of cryosurgery
o The destructive effect of freezing tissue has been categorized into two major mechanisms-
Immediate cell destruction.
Delayed cell destruction.
Application techniques
Probe freezing: It is done by direct application of a probe tip to the lesion. The cryogen circulates through the probe tip and super cools it, when allowed to contact the target tissue. Probe freezing can be accomplished by one of the two mechanisms: contact freezing and penetration freezing.
In contact freezing, firm contact is made between the cryoprobe and the target tissue.
While in penetration freezing probe penetrates the target tissue, providing a large area of direct contact.
Spray freezing: It is done by direct application of the liquid nitrogen to the tissue and is the most destructive method. Liquid nitrogen is delivered to the target tissue at such a volume and velocity that it evaporates at the edge of the lesion. The spray orifice allows deeper and faster tissue penetration than the probe tip but the probe method is safer and more precise.
Benefits of Cryosurgery in Veterinary Medicine
Painless.
No Preparation.
No post op care.
No open wounds – No Bleeding.
No suturing.
No general anaesthesia – safe for older animals.
Rapid treatment time – only seconds.
Cost Effective.
Pressure to treat lesion.
Pinpoint Accuracy.
CryoProbe’s different micro applicators tips allow pinpoint accuracy to treat skin lesions from 1mm to 8mm in size.
Blue dot applicator Applications 1-3 mm.
White dot applicator Applications 2-4 mm.
Green dot applicator Applications 3-6 mm.
Yellow dot applicator Applications 4-10 mm.
Lesions
With the CryoProbe you will be able to treat (but not limited) to the following lesions successfully:
Perianal Adenomas.
Epuli.
Papilloma.
Lick Granulomas.
Warts.
Small Sarcoids.
Eye Lid Tumors.
You will be able to quickly and easily treat skin lesions that you could not treat before without undesired side effects.
Disadvantages of Cryosurgery
As with the advantages of cryosurgery, the disadvantages can also be categorized into those for the clinician and those for the patient.
Disadvantages for the clinician include the following:
Liquid nitrogen needs to be delivered and stored. A liquid nitrogen generator may be purchased. If that is not done, nitrous oxide tanks or other supplies will need to be replenished as needed.
Cardiovascular disease is the leading cause of death globally and accounts for nearly 1 trillion dollars in costs annually.
A heart attack strikes 2.8 million Indians and 7,35,000 Americans each year and heart disease is the number one killer world wide.
Heart attacks are a form of ACS- Acute coronary syndrome.
ACS is when the arteries that carry blood, oxygen and nutrients get blocked.
A heart attack also is known as myocardial infarction
Cryotechniques and their methods.
1.cryotomy and What is cryopreservation.
2.cryopreservation of cells, tissue, and organisms.
3.freeze fracture
4.freeze drying.
5.freezable tissues.
6.mechanism of cryopreservation.
7.cryopreservation of embryos.
for more such content reffer to www.faunafondness.com
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Operation “Blue Star” is the only event in the history of Independent India where the state went into war with its own people. Even after about 40 years it is not clear if it was culmination of states anger over people of the region, a political game of power or start of dictatorial chapter in the democratic setup.
The people of Punjab felt alienated from main stream due to denial of their just demands during a long democratic struggle since independence. As it happen all over the word, it led to militant struggle with great loss of lives of military, police and civilian personnel. Killing of Indira Gandhi and massacre of innocent Sikhs in Delhi and other India cities was also associated with this movement.
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3. INTRODUCTION
WHAT IS CRYONICS
GENESIS OF CRYONICS
ACTUAL PROCESS OF PRESERVING
NANOROBOTS
FINANCIAL ISSUES
ADVANTAGES AND DISADVANTAGES
CONCLUSION
4. This technology uses atoms with a view
to creating a desired product.
The term nanotechnology has been a
combination of two terms,”nano”and
“ technology”.
The term nano is derived from a Greek
word “nanos” which means “dwarf”.
Thus nanotechnology is dwarf
technology. A nanometer is one billionth
of a metre.
5. The most important application of nanotechnology is
cryonics.
Cryonics – derived from Greek language, kryos meaning icy
cold.
Cryonics is the low temperature preservation of living things
who/which can no longer be sustained by contemporary
medicine, with the hope that healing and resuscitation may be
possible in future.
Preserving to the point where molecular physical decay
completely stops this state is known as cryonics suspension.
6. The idea of cryonics was proposed by Robert Ettinger a
Physics teacher, after he read a book The Jameson Satellite
by Neil R Jones in the year 1931.
Later he published the books so called , The penultimate
Trumph and The Prospects of Immortality in the years 1948
and 1962 respectively, which is a modern era of cryonics.
Robert Ettinger - ‘originator and pioneer of cryonics’.
The word cryonics was proposed by Kerl Werner in 1965.
Later it was developed by CSM,CSC(not in use know),
CI, Alcor.
Contd.,
7. The first person Dr. James Bedford, a 73 -year-old
Psychology professor, was frozen with the intent of future
resuscitation by CSC on January 12 , 1967.
In CI the first person frozen there was Ettinger’s mother and
later his two wives Elaine and Mae in the year 1977.
Totally 306 bodies are preserved by cryonics in CI, Alcor and
Kriorus (Russia) till the date of 1 May 2011.
8. Dr. James Bedford, a 73
-year-old Psychology
professor.
9. There are mainly five steps in preserving a living thing by using
the present technology:
1.Stabilize, cool, and transport the patient to the Cryonics
Institute.
2. Perfuse the patient with cryoprotective solutions .
10. 3.Lowers the patient temperature by adding the dry ice day to day until
the body reaches -79 degree centigrade.
4.Body is slowly lowered into the liquid nitrogen until it is submerged in
completely, by the completion of process temperature is -196 degree
centigrade.
12. On the way to Alcor, blood circulation is maintained and
patient is injected with medicine to minimize problems with
frozen tissues.
At Alcor the body is cooled to 5 Degrees.
Contd.,
13. Body is replaced with glycerol
to reduce ice formation.
The patient is placed in cold
silicone oil, chilling the body
to -79 degree centigrade.
Then cooled over 5 days in
liquefied nitrogen to -196
degree centigrade .
15. Current medical science does not have the tools to fix damage
that occurs at the cellular and molecular level, and damage to
these systems is the cause of vast majority of fatal illness”.
Cryonics basically deals with cells, these cells are in the order
of nanometers.
At present there is no other technology which deals with such
minute cells.
Only nanotechnology has the ability to deal with cells.
16. Robots are programmed to
deliver drugs to particular cells
that are damaged.
Nanoprobe has the capability of
carrying ligands.
17. The Cryonics Institute in Clinton Township, Michigan,
charges a minimum of $28,000 and rarely more than
US$200,000, depending on the cryonics organization, the type
of cryopreservation neuro/whole body and the procedures
used.
This is due to storing a cryopreserved person is in liquid
nitrogen, fracturing of the brain occurs, to overcome this
cooling from -130 to -196 degree centigrade.
18. It is possible that the frozen people will be repairable and
relabelled as potentially alive.
Life extension.
Super medicine for fatal disease.
Disadvantages:-
Population will be uncontrolled .
Cryonics can’t restore the life to the people whose brain has
been physically destroyed.
Practical implementation is quite difficult & expensive.
19. In medicine, cryonics, was once considered on the outer edge,
but is now moving closer to reality ? which means someone
who died and was frozen last week may have a future again.
Cryonics and nanotechnology form a useful pair.
Cryonics can transport a terminally ill patient to future
medical technology.