Gene therapy is a technique used to substitute defective genes that cause diseases with functional genes. It involves identifying the defective gene, extracting DNA, inserting a functional gene, and reinserting the modified DNA. There are two main types of gene therapy - somatic cell gene therapy, which treats only the individual and is not hereditary, and germline cell gene therapy, which could affect future generations but may be most effective. Gene therapy delivers the new genes via viral or bacterial vectors and holds promise to cure genetic diseases but also poses risks such as immune reactions or unintended effects.
Gene therapy is an experimental technique that uses genes to treat or prevent disease. The slides explain what is gene tharapy? Types of gene therapy. http://www.wesrch.com/
Gene therapy is an experimental technique that uses genes to treat or prevent disease. The slides explain what is gene tharapy? Types of gene therapy. http://www.wesrch.com/
Advances in biochemistry and molecular biology have helped to understand the genetic basis of inherited diseases.
Gene therapy was once considered a fantasy (imaginary).
It was a dream of the researchers to replace the defective genes with good ones and cure the genetic disorders.
GENE THERAPY: TYPES, METHODS, FACTORS AND STANDARDS AND ITS APPLICATION IN HEALTHCARE FIELD
INVIVO THERAPY AND EXVIVO THERAPY
CHEMICAL AND PHYSICAL METHODS TO CARRY ON GENE THERAPY
DEFECTIVE GENE IDENTIFICATION IN GENE THERAPY AND TREATMENT OF GENETICALLY AFFECTED GENE BY GENE THERAPY
Gene Therapy, Somatic cell gene therapy, germ line gene therapy, classical gene therapy, non-classical gene therapy, targets of gene therapy, barriers of gene therapy, ex vivo gene therapy, in vivo gene therapy, vectors for gene delivery, antisense therapy
this helps to understand the normal techniques related to biotechnology in a simple manner and provides you broad idea about the subject. A brief knowledge about the topic is presented in this presentation.
These slide include gene therapy defines with their types like Germ line gene therapy,Somatic gene therapy.
with Need of Gene therapy
strategies of gene therapy
Methods of Gene transfer & with
GENE THERAPY FOR INHERITED DISORDERS
Advances in biochemistry and molecular biology have helped to understand the genetic basis of inherited diseases.
Gene therapy was once considered a fantasy (imaginary).
It was a dream of the researchers to replace the defective genes with good ones and cure the genetic disorders.
GENE THERAPY: TYPES, METHODS, FACTORS AND STANDARDS AND ITS APPLICATION IN HEALTHCARE FIELD
INVIVO THERAPY AND EXVIVO THERAPY
CHEMICAL AND PHYSICAL METHODS TO CARRY ON GENE THERAPY
DEFECTIVE GENE IDENTIFICATION IN GENE THERAPY AND TREATMENT OF GENETICALLY AFFECTED GENE BY GENE THERAPY
Gene Therapy, Somatic cell gene therapy, germ line gene therapy, classical gene therapy, non-classical gene therapy, targets of gene therapy, barriers of gene therapy, ex vivo gene therapy, in vivo gene therapy, vectors for gene delivery, antisense therapy
this helps to understand the normal techniques related to biotechnology in a simple manner and provides you broad idea about the subject. A brief knowledge about the topic is presented in this presentation.
These slide include gene therapy defines with their types like Germ line gene therapy,Somatic gene therapy.
with Need of Gene therapy
strategies of gene therapy
Methods of Gene transfer & with
GENE THERAPY FOR INHERITED DISORDERS
This is a lecture I put together as part of a Medical Ethics course that I am teaching at Bowling Green State University this summer. It is about ethical issues related to genetic screening and counseling, and prenatal genetic diagnosis.
Ethical and Legal Issues Related to Medical Genetics Rayhan Shahrear
Define ethics and bioethics.
State the major ethical issues related to medical genetics.
Outline the uniqueness of medical genetics.
Outline the relevant ethical principles in medicine.
Discuss some ethical dilemmas that arise in the genetic clinic.
Explain the ethical dilemmas and public interest.
Dr. Najnin Akhter
Phase-A, Year-2, Block-6
Guided by Prof. K M Shamim
Gene therapy is an experimental technique that uses genes to treat or prevent disease which allow doctors to treat a disorder by inserting a gene into a patient’s cells instead of using drugs or surgery.
Gene therapy is an experimental treatment that involves introducing genetic material into a person’s cells to fight or prevent disease. Researchers are studying gene therapy for a number of diseases, such as severe combined immuno-deficiencies, hemophilia, Parkinson's disease, cancer and even HIV, through a number of different approaches (see video: 'Gene Therapy a new tool to cure human diseases'). A gene can be delivered to a cell using a carrier known as a “vector.” The most common types of vectors used in gene therapy are viruses. The viruses used in gene therapy are altered to make them safe, although some risks still exist with gene therapy. The technology is still in its infancy, but it has been used with some success.
In this slide, You will get to learn abut Gene Therapy and different types of gene therapy. Various method of Gene Therapy and Advantage & Disadvantage and Recent advances in Gene Therapy.
presentation on battles over human embryos and stem cell research ......For any doubts in presentation contact
Gandhi Manikandan
https://www.facebook.com/gandhi.manikandan.39
or email gk.manikandan1996313@gmail.com
My first ppt with so much effort - hope u like it n many are pictures without explanation u can use the link in few slides for additional information
Thank you.
Generating a custom Ruby SDK for your web service or Rails API using Smithyg2nightmarescribd
Have you ever wanted a Ruby client API to communicate with your web service? Smithy is a protocol-agnostic language for defining services and SDKs. Smithy Ruby is an implementation of Smithy that generates a Ruby SDK using a Smithy model. In this talk, we will explore Smithy and Smithy Ruby to learn how to generate custom feature-rich SDKs that can communicate with any web service, such as a Rails JSON API.
Epistemic Interaction - tuning interfaces to provide information for AI supportAlan Dix
Paper presented at SYNERGY workshop at AVI 2024, Genoa, Italy. 3rd June 2024
https://alandix.com/academic/papers/synergy2024-epistemic/
As machine learning integrates deeper into human-computer interactions, the concept of epistemic interaction emerges, aiming to refine these interactions to enhance system adaptability. This approach encourages minor, intentional adjustments in user behaviour to enrich the data available for system learning. This paper introduces epistemic interaction within the context of human-system communication, illustrating how deliberate interaction design can improve system understanding and adaptation. Through concrete examples, we demonstrate the potential of epistemic interaction to significantly advance human-computer interaction by leveraging intuitive human communication strategies to inform system design and functionality, offering a novel pathway for enriching user-system engagements.
Transcript: Selling digital books in 2024: Insights from industry leaders - T...BookNet Canada
The publishing industry has been selling digital audiobooks and ebooks for over a decade and has found its groove. What’s changed? What has stayed the same? Where do we go from here? Join a group of leading sales peers from across the industry for a conversation about the lessons learned since the popularization of digital books, best practices, digital book supply chain management, and more.
Link to video recording: https://bnctechforum.ca/sessions/selling-digital-books-in-2024-insights-from-industry-leaders/
Presented by BookNet Canada on May 28, 2024, with support from the Department of Canadian Heritage.
Smart TV Buyer Insights Survey 2024 by 91mobiles.pdf91mobiles
91mobiles recently conducted a Smart TV Buyer Insights Survey in which we asked over 3,000 respondents about the TV they own, aspects they look at on a new TV, and their TV buying preferences.
DevOps and Testing slides at DASA ConnectKari Kakkonen
My and Rik Marselis slides at 30.5.2024 DASA Connect conference. We discuss about what is testing, then what is agile testing and finally what is Testing in DevOps. Finally we had lovely workshop with the participants trying to find out different ways to think about quality and testing in different parts of the DevOps infinity loop.
UiPath Test Automation using UiPath Test Suite series, part 3DianaGray10
Welcome to UiPath Test Automation using UiPath Test Suite series part 3. In this session, we will cover desktop automation along with UI automation.
Topics covered:
UI automation Introduction,
UI automation Sample
Desktop automation flow
Pradeep Chinnala, Senior Consultant Automation Developer @WonderBotz and UiPath MVP
Deepak Rai, Automation Practice Lead, Boundaryless Group and UiPath MVP
LF Energy Webinar: Electrical Grid Modelling and Simulation Through PowSyBl -...DanBrown980551
Do you want to learn how to model and simulate an electrical network from scratch in under an hour?
Then welcome to this PowSyBl workshop, hosted by Rte, the French Transmission System Operator (TSO)!
During the webinar, you will discover the PowSyBl ecosystem as well as handle and study an electrical network through an interactive Python notebook.
PowSyBl is an open source project hosted by LF Energy, which offers a comprehensive set of features for electrical grid modelling and simulation. Among other advanced features, PowSyBl provides:
- A fully editable and extendable library for grid component modelling;
- Visualization tools to display your network;
- Grid simulation tools, such as power flows, security analyses (with or without remedial actions) and sensitivity analyses;
The framework is mostly written in Java, with a Python binding so that Python developers can access PowSyBl functionalities as well.
What you will learn during the webinar:
- For beginners: discover PowSyBl's functionalities through a quick general presentation and the notebook, without needing any expert coding skills;
- For advanced developers: master the skills to efficiently apply PowSyBl functionalities to your real-world scenarios.
Connector Corner: Automate dynamic content and events by pushing a buttonDianaGray10
Here is something new! In our next Connector Corner webinar, we will demonstrate how you can use a single workflow to:
Create a campaign using Mailchimp with merge tags/fields
Send an interactive Slack channel message (using buttons)
Have the message received by managers and peers along with a test email for review
But there’s more:
In a second workflow supporting the same use case, you’ll see:
Your campaign sent to target colleagues for approval
If the “Approve” button is clicked, a Jira/Zendesk ticket is created for the marketing design team
But—if the “Reject” button is pushed, colleagues will be alerted via Slack message
Join us to learn more about this new, human-in-the-loop capability, brought to you by Integration Service connectors.
And...
Speakers:
Akshay Agnihotri, Product Manager
Charlie Greenberg, Host
Essentials of Automations: Optimizing FME Workflows with ParametersSafe Software
Are you looking to streamline your workflows and boost your projects’ efficiency? Do you find yourself searching for ways to add flexibility and control over your FME workflows? If so, you’re in the right place.
Join us for an insightful dive into the world of FME parameters, a critical element in optimizing workflow efficiency. This webinar marks the beginning of our three-part “Essentials of Automation” series. This first webinar is designed to equip you with the knowledge and skills to utilize parameters effectively: enhancing the flexibility, maintainability, and user control of your FME projects.
Here’s what you’ll gain:
- Essentials of FME Parameters: Understand the pivotal role of parameters, including Reader/Writer, Transformer, User, and FME Flow categories. Discover how they are the key to unlocking automation and optimization within your workflows.
- Practical Applications in FME Form: Delve into key user parameter types including choice, connections, and file URLs. Allow users to control how a workflow runs, making your workflows more reusable. Learn to import values and deliver the best user experience for your workflows while enhancing accuracy.
- Optimization Strategies in FME Flow: Explore the creation and strategic deployment of parameters in FME Flow, including the use of deployment and geometry parameters, to maximize workflow efficiency.
- Pro Tips for Success: Gain insights on parameterizing connections and leveraging new features like Conditional Visibility for clarity and simplicity.
We’ll wrap up with a glimpse into future webinars, followed by a Q&A session to address your specific questions surrounding this topic.
Don’t miss this opportunity to elevate your FME expertise and drive your projects to new heights of efficiency.
Key Trends Shaping the Future of Infrastructure.pdfCheryl Hung
Keynote at DIGIT West Expo, Glasgow on 29 May 2024.
Cheryl Hung, ochery.com
Sr Director, Infrastructure Ecosystem, Arm.
The key trends across hardware, cloud and open-source; exploring how these areas are likely to mature and develop over the short and long-term, and then considering how organisations can position themselves to adapt and thrive.
2. WHAT GENE THERAPY?
• A technique used to substitute defective
genes in an individual with genes that do
work.
• These defects cause diseases and illnesses.
• The scientific world is trying to understand the
way our body reacts without these genes and
why our genes sometimes aren’t “on.”
3. When did it Start?
• James Watson and Francis Crick learned about the double helix of DNA in 1953.
• Gene therapy evolved in the Recombinant DNA Era, in the 1980s.
4. What Happens?
1. Cut a piece of DNA with restriction
enzymes
2. Insert the pieces into a plasmid
3. Analyze gene
4. Define defect or disease
5. Make a plan for treatment (example in
steps 6 and 7)
6. Replace defective cells with “normal”
cells
7. Insert new cells into patient through
vectors
5. Types of Gene Therapy
• Somatic Cells: • Germline Cells:
1. Majority of cells in the 1. Cells exist in sperm
human body and eggs
2. Not passed on to 2. Potential of having
future generations negative effect for
3. Less controversial and future generations
more effective if 3. Potentially most
started sooner effective
6. Somatic Cells
• Cells are removed from
body before treatment.
• Grown in lab, fix gene and
insert back into body
through blood stream.
• Many cells to work with.
• Higher risk for older children
or young adults.
• Used to treat illnesses such
as cancer, cystic fibrosis, and
muscular dystrophy.
7. Germline Cells
• Correct abnormalities of
gene involved in
reproduction.
• Abnormalities are seen
before becoming tissue.
• Controversial- “playing
God” with unformed tissue.
• Most effective during
embryonic stage.
• Potential negative affects
on future generations.
8. Vector Deliveries
1. EX-VIVO METHOD
• Outside living body.
• “Normal cells” are inserted in
vector.
• Blood cells with defective gene
are removed from patient.
• Patient’s blood is mixed with
viruses from vector.
• Combination of new and old cells
are put back into the patient.
• Protein is produced to fight
disease.
9. Vector Deliveries
2. IN-VIVO METHOD
• Inside living body.
• Does not use patient’s cells.
• Vectors are given “new” and
“affective” cells.
• New cells put into patient’s
bloodstream.
• New cells bind with targeted
diseased cells.
• Reverses effect of gene.
10. BACTOFECTION:
Newer method of gene therapy.
• Uses bacteria for a direct transfer of the gene to the
individual.
• Bacterial strains deliver the genes to the plasmid and
into the cells.
• Bacteria used as “vehicle” to transfer genetic
information to the cell.
11. Positive Aspects
• Has “incredible therapeutic
potential.”
• Potential to find cures to
genetic diseases.
• Defects can be eliminated
and not passed on to future
children.
• Stops suffering of patient and
family.
12. Negative Aspects
• Immune system can destroy the
vector.
• Very expensive for patient.
• “Make the rich, richer, and the
poor, poorer.”
• “Designer babies” may be made.
• Harmful effects.
• Against religious beliefs.
• “Playing with God and Mother
Nature.”
13. WORKS CITED
• Bergeson, Emilie R. "The Ethics of Gene Therapy." The Ethics of Gene Therapy. Web.
15 May 2012.
<http://www.ndsu.edu/pubweb/~mcclean/plsc431/students/bergeson.htm>.
• Bose, Debopriya. “Gene Therapy Pros and Cons.” Web. 15. 2012.
<http://www.buzzle.com/articles/gene-therapy-pros-and-cons.html>
• "Gene Therapy Reverses Type 1 Diabetes in Mice, Study Finds." ScienceDaily.
ScienceDaily, 06 June 2011. Web. 9 May 2012.
<http://www.sciencedaily.com/releases/2011/06/110606092738.htm>.
• Nature.com. Nature Publishing Group. Web. 15 May 2012.
<http://www.nature.com/gt/journal/v13/n2/full/3302635a.html>.
• "Types of Gene Therapy." « Walesgenepark.co.uk. Web. 15 May 2012.
<http://www.walesgenepark.co.uk/types-of-gene-therapy-2>.