#colloidal-mill

1. Guru Nanak Institute of
Pharmaceutical Science and
Technology
Colloid mill
Presented by:-
Palash Ghosal (66)
Tapabrata Dutta(71)
Surovi Das(77)
Sourav Dutta (85)
Salman Akhtar Mondal(86)

2. CONTENT
Introduction
Principle
Parts
Mechanism
Application
Advantage
Disadvantage
Conclusion
Reference
Question & Answer

3. INTRODUCTION
 Colloid mill is a machine that is used to
reduce the particle size of a solid in
suspension in a liquid ,or to reduce the
droplet size in emulsions.
 When a liquid is suspended in another
liquid, meaning they are immiscible, this
machine is used to alternatively to
reduce the size of this droplet.
 A high level of hydraulic shear stress is
applied on the fluid which results in
disrupting and breaking down the
structure.

4. PRINCIPLE
Works on the principle of ROTOR AND
STATOR
Size reduction is affected due to SHEARING
Rotor become high speed
High level of hydraulic shear applied
Shear rate leads to smaller droplets
Particle size done by modifying the gap
between Rotor and Stator
Drain pipe removes the final product
[1,2,4]

5. PARTS
To feed the material hopper is used which
are attached to the rotor and Stator
assembly.
Rotor and Stator which are made of
stainless steel may be rough or finish
surface is used for Shearing the
mixture.
Motor assembly to rotate.
A discharge point for outlets
the mixture and a auto circular
tube.
[1,2]

6. MECHANISM
The material is placed into the mill
though the inlet hopper.
It is then passed through the
narrow gap between the rotor
having and stator and thus
reduced the fine particle size. By
the help of pulverization.
Then it will come to the auto
circular tube ,until we allow it to
came out from the discharge port
The rotor speed is 3000 to
20000rpm and can
produce particle size of 1𝜇
[1,2,3]

7. APPLICATION
Used for comminution of solids
Used for formulation of Colloidal
dispersions, Suspensions, Emulsions,
Ointment
Increased the stability of Suspension,
Emulsion
Used to grinding, dispersing,
homogenizing the ointment, gels and
high viscus fluid
[1,3,4]

8. ADVANTAGE
Homogenization intensity and duration
The viscosity of the continuous phase.
The shear force within the gap between the spinning rotor and the
stationary stator.
Clearance rate between the rotor and the stator.
Colloid mill is easy to clean after use.
High capacity and minimal requirements
No pressure is required for ionization.
easily adjustable.
Reduced wear as a result of the construction of the rotor-stator
with toughened steel/corundum.
[1,3]

9. DISADVANTAGE
 It has no wide application in solids.
 Wear of the rotating plates.
 No fine grinding.
 Consumes energy though still dependent on some factors.
[1,2]

10. CONCLUSION
Colloidal mill is highly recommended in
Pharmaceutical, beverage, paint, textiles,
and food processing industries, it can
produce high output in less time, easy to
operate and clean. A colloid mill is a
machine that used to reduce the particle
size of a solid in suspension in a liquid or
to reduce the droplet size in emulsions.
Colloid mills work on the rotor-stator
principle.
[1,4]

11. REFERENCE
1) David, B. T. and Paul, B. (2006). Remington: The
Science and of Pharmacy. 21st edition. Lippincott
Williams and Wilkins, USA.
2) George D. Saravacos, and Athanasios E.
Kostaropoulos (2002). Handbook of Food Processing
Equipment. Kluwer Academic/Plenum Publishers, New
York.
3)Lieberman, Herbert A, Lachman, Leon (2009),
Industrial pharmacy: Pharmaceutical dosage form-
milling. Banglore, Pune. ISBN: 978-81-239-1679-8.
4)Mehta RM, Pharmaceutics-I: Size reduction
(1996), Page no: 117-118.