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There are three types of cofactors :
 Prosthetic groups
 Coenzymes
 Activators
Prosthetic group
• Organic molecules
• Attach permanently to
enzyme
• Eg.
Hb contains haem ( iron ) and
it is bound to protein
Haem enables Hb to carry
oxygen.
Coenzymes
• Small , non protein
molecules
• They help enzymes
and substrate to bond
• Not attached
permanently
• Eg.
NAD from nicotinic acid
is coenzyme for
dehydrogenase
enzymes
Activators
• Inorganic metal ions
• Form temporary
attachment to enzyme and
change active site
• Eg.
Mg (synthesis of protein)
Ca (nerve impulse,
muscle contraction)

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Cofactor

  • 1. There are three types of cofactors :  Prosthetic groups  Coenzymes  Activators
  • 2. Prosthetic group • Organic molecules • Attach permanently to enzyme • Eg. Hb contains haem ( iron ) and it is bound to protein Haem enables Hb to carry oxygen.
  • 3. Coenzymes • Small , non protein molecules • They help enzymes and substrate to bond • Not attached permanently • Eg. NAD from nicotinic acid is coenzyme for dehydrogenase enzymes
  • 4. Activators • Inorganic metal ions • Form temporary attachment to enzyme and change active site • Eg. Mg (synthesis of protein) Ca (nerve impulse, muscle contraction)

Editor's Notes

  1. Title slide.