The document discusses codon optimization, which is a process that improves gene expression and increases translational efficiency of a gene of interest. It does this by accounting for the codon bias of the host organism. Codons are three nucleotide sequences in RNA that specify which amino acid is needed for protein synthesis. The document also lists some common codon optimization tools like Twistbioscience, Idtdna, and Genscript.

1. CODON OPTIMIZATION
By
HARSHITHA EBBALI
2021502009
I M.Sc Bioinformatics

2. CONTENTS
# Glimpse on Central dogma
# What are Codons
# What is Codon Optimization
# Why Codon Optimization

3. CENTRAL DOGMA

5. CODONS:

6. CODONS
• Codons are three nucleotide based in RNA
• It specify amino acid needed for protein

8. CODON OPTIMIZATION
• Codon optimization is a process used to improve gene
expression and increase the translational efficiency of a
gene of interest by accommodating codon bias of the host
organism.
• Codon usage biases are found in all eukaryotic and
prokaryotic genome
CGA
CGG Argenine
CGU
CGC

9. CODON OPTIMIZATION

12. Codon optimization tools:
• Twistbioscience
• Idtdna
• Genscript
• Vectorbuilder
• Genewiz