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UNIVERSIDAD AUTÓNOMA DE CIUDAD JUÁREZ

              CLORHEXIDINE

         DRA. AMARIS MENDOZA ASTRAIN

          DR. ALFREDO   NEVAREZ RASCÓN
History


   Chlorhexidine developed in the 1940s in England,
    and was released in 1954 as an antiseptic for skin
    wounds. Use in dentistry,initially for disinfection
    of the mouth, and from 1970 he popularized the use
    of chlorhexidine mouthwash capable of inhibiting the
    formation of plaque and gingivitis development.
   Chlorhexidine needs to be protected from
    light as it breaks easily.
   At high temperatures and decomposes
    into chloroaniline the presence of organic
    matter not inactive
composition

   Chlorhexidine
    is an antiseptic bisbiguanidico. This compound
    is a strong base and dicationica at pH
    levels over 3.5. Nature dicatiónicaof
    chlorhexidine makes it
    extremely interactive with anions, which
    isrelevant to their efficacy, safety and local
    side effects.
uses in dentistry
   Oral infections for various reasons including those
    produced by rubbing of dentures
   Prevention of infection in oral surgery
   Chemotherapeutic prevention of dental caries
   As a disinfectant of cavities prior to sealing
Commercial Presentations
   Spray


   Gel

   mouthwash




                Fig. 1
                http://www.lacer.es/wps/wcm/connect/04ff9a00463daaf
                0926e9bc9bb9f72a0/30
Chlorhexidine spray
   It has been marketed spray
    chlorhedine to the 0.1% and 0.2%
   Prevention and treatment
    of gingivitis
   Very delicate state of the
    gingiva: Lets you
    apply chlorhexidinewithout
    touching the affected area
   When rinsing is painful
                                       Fig 2
   Special Patients (physical or      http://csimg.mercamania.es/s
    mental disabilities)               rv/ES/29045327247742/T/34
                                       0x340/C/FFFFFF/url/lacer-
                                       clorhexidina-spray-40.jpg
Chlorhexidine Gel

   The gel allows the
    selection of sites
    affected, leaving the
    healthy free,
    thus increasing the
    safety
    margin, chlorhexidine g   Fig. 3
    els are suitable for      http://www.farmahouse.com/images/clorh
                              exidina%20gel.JPG
    prevention and care
    of critical areas.
Chlorhexidine mouthwash
   Is used in
    concentrations of 0.12 to 0.2%,
    Indications of rinses
   Cases of excessive formation of plaque.

   Prevention in the treatment of gingivitis.

   People with difficulty performing normal
    dental hygiene.

   Mouthwash before or after surgery.           Fig 4
                                                 http://www.dermofactory.com/160617
   Prevention of dental caries.                 6-1155-thickbox/lacer-clorhexidina-
                                                 colutorio-200-ml.jpg
Precautions
   It is exclusively for local use and not be swallowed
   You can leave a bitter taste after application will
    be enhanced if the mouth is rinsed immediately
   Dilute reduces its antimicrobial effect
   Do not use continuously for more than 2-
    3 months, and always underprofessional
    supervision, as it may have unwanted side effects.
side effects
   The adverse effects of this are usually mild and
    transient inspecial brown spots on the teeth,
    tongue, prosthesis and silicate and
    resin restorations and temporary alteration of taste
    perception and scaling of the oral mucosa.
trademarks
   Paroex.
    Cariax gingival.
    PerioAid alcohol-free.
    Lacer.
   Eludril


                              Fig. 5
                              http://scielo.isciii.es/scielo.php?pid=s11
                              38123x2005000400007&script=sci_artt
                              ext
advantage
   Bactericidal action: antimicrobial effects as good as sodium
    hypochlorite
   relatively inocua
   It has no unpleasant odo
   Residual activity of several hours after instrumentation
   Easy storage and handling

   low toxicity
Disadvantages
   Staining of the teeth
   staining lingual
   Bitter, metallic taste
   Possible peeling of the oral mucosa
   Stains are accentuated if the patient drinks red
    wine, coffee, tea, and a smoking
Bibliography
   http://www.odontologosecuador.com/espanol/artodontologos
    /gluconato_dental.htm


    http://www.encolombia.com/odontologia/odontonet/monogra
    fia-clorhexidina4.htm
   http://scielo.isciii.es/scielo.php?pid=s1138-
    123x2005000400007&script=sci_arttext

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Clorhexidine

  • 1. UNIVERSIDAD AUTÓNOMA DE CIUDAD JUÁREZ CLORHEXIDINE DRA. AMARIS MENDOZA ASTRAIN DR. ALFREDO NEVAREZ RASCÓN
  • 2. History  Chlorhexidine developed in the 1940s in England, and was released in 1954 as an antiseptic for skin wounds. Use in dentistry,initially for disinfection of the mouth, and from 1970 he popularized the use of chlorhexidine mouthwash capable of inhibiting the formation of plaque and gingivitis development.
  • 3. Chlorhexidine needs to be protected from light as it breaks easily.  At high temperatures and decomposes into chloroaniline the presence of organic matter not inactive
  • 4. composition  Chlorhexidine is an antiseptic bisbiguanidico. This compound is a strong base and dicationica at pH levels over 3.5. Nature dicatiónicaof chlorhexidine makes it extremely interactive with anions, which isrelevant to their efficacy, safety and local side effects.
  • 5. uses in dentistry  Oral infections for various reasons including those produced by rubbing of dentures  Prevention of infection in oral surgery  Chemotherapeutic prevention of dental caries  As a disinfectant of cavities prior to sealing
  • 6. Commercial Presentations  Spray  Gel  mouthwash Fig. 1 http://www.lacer.es/wps/wcm/connect/04ff9a00463daaf 0926e9bc9bb9f72a0/30
  • 7. Chlorhexidine spray  It has been marketed spray chlorhedine to the 0.1% and 0.2%  Prevention and treatment of gingivitis  Very delicate state of the gingiva: Lets you apply chlorhexidinewithout touching the affected area  When rinsing is painful Fig 2  Special Patients (physical or http://csimg.mercamania.es/s mental disabilities) rv/ES/29045327247742/T/34 0x340/C/FFFFFF/url/lacer- clorhexidina-spray-40.jpg
  • 8. Chlorhexidine Gel  The gel allows the selection of sites affected, leaving the healthy free, thus increasing the safety margin, chlorhexidine g Fig. 3 els are suitable for http://www.farmahouse.com/images/clorh exidina%20gel.JPG prevention and care of critical areas.
  • 9. Chlorhexidine mouthwash  Is used in concentrations of 0.12 to 0.2%, Indications of rinses  Cases of excessive formation of plaque.  Prevention in the treatment of gingivitis.  People with difficulty performing normal dental hygiene.  Mouthwash before or after surgery. Fig 4 http://www.dermofactory.com/160617  Prevention of dental caries. 6-1155-thickbox/lacer-clorhexidina- colutorio-200-ml.jpg
  • 10. Precautions  It is exclusively for local use and not be swallowed  You can leave a bitter taste after application will be enhanced if the mouth is rinsed immediately  Dilute reduces its antimicrobial effect  Do not use continuously for more than 2- 3 months, and always underprofessional supervision, as it may have unwanted side effects.
  • 11. side effects  The adverse effects of this are usually mild and transient inspecial brown spots on the teeth, tongue, prosthesis and silicate and resin restorations and temporary alteration of taste perception and scaling of the oral mucosa.
  • 12. trademarks  Paroex.  Cariax gingival.  PerioAid alcohol-free.  Lacer.  Eludril Fig. 5 http://scielo.isciii.es/scielo.php?pid=s11 38123x2005000400007&script=sci_artt ext
  • 13. advantage  Bactericidal action: antimicrobial effects as good as sodium hypochlorite  relatively inocua  It has no unpleasant odo  Residual activity of several hours after instrumentation  Easy storage and handling  low toxicity
  • 14. Disadvantages  Staining of the teeth  staining lingual  Bitter, metallic taste  Possible peeling of the oral mucosa  Stains are accentuated if the patient drinks red wine, coffee, tea, and a smoking
  • 15. Bibliography  http://www.odontologosecuador.com/espanol/artodontologos /gluconato_dental.htm  http://www.encolombia.com/odontologia/odontonet/monogra fia-clorhexidina4.htm  http://scielo.isciii.es/scielo.php?pid=s1138- 123x2005000400007&script=sci_arttext