1. Parasitic Infections: Clinical Manifestations, Diagnosis and Treatment Lennox K. Archibald, MD, PhD, FRCP, DTM&H Hospital Epidemiologist University of Florida

7. Diagnosis?

16. Diagnosis?

18. Trophozoites with ingested RBC

19. Trophozoites in colon tissue (H & E stain)

20. Cyst (wet mount)

33. Diagnosis? Case 3 & 4

34. Three cysts stained pale red are seen in the center with this acid fast stain

35. Modified acid-fast stain of stool showing red oocysts of Cryptosporidium parvum against the blue background of coliforms and debris

60. And don’t forget baggage malaria!

65. Diagnosis?

67. An intact macrophage practically filled with amastigotes (arrows),

72. Hepatosplenomegaly

80. AIDS Patient

81. AIDS Patient

82. Toxoplasma gondii cyst in brain tissue with H & E stain (100x)

94. Thick smear

95. Thin smear Maltese cross

96. Diagnosis??

103. Diagnosis?

112. Diagnosis?

117. Diagnosis

125. Diagnosis?

132. Diagnosis?

141. Diagnosis ?

152. Chronic intestinal schistosomiasis

160. S. mansoni Stool S. haematobium Urine S. japonicum

162. Diagnosis?

164. Blood smear

165. African trypanosomiasis Trypanosoma brucei gambiense

166. Tsetse fly

170. Diagnosis?

171. Blood smear

172. Reduviid bug (assassin bug)

178. Diagnosis?

180. Beef Tapeworm

197. General rules of treatment of metazoa Nematodes Intestinal Mebendazole or Albendazole Tissue Albendazole Filiariae Ivermectin, doxycycline Cestodes Praziquantel, Albendazole, Niclosamide Trematode Praziquantel Ectoparasites Permethrin, Ivermectin

198. This is just the beginning of a great adventure in infectious diseases Sine qua non : history and physical examination

199. Thank you Lennox K. Archibald, MD, PhD, FRCP [email_address]