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CKB
Disampaikan pada pemantapan profesi KGD:
Ns. Arcellia Farosyah P., S.Kep., MSc
Hukum Monroe Kelly
¡ Darah
¡ Cairan serebrospinal
¡ Parenkim Otak
PENINGKATAN TIK
PO2 & PCO2
¡ PCO2 tinggi:
vasodilatasi
¡ Asidemia: aliran darah ke
otak meningkat
¡ PCO2 rendah:
vasokonstriksi
¡ Alkalemia: aliran darah ke
otak berkurang
CPP = MAP - ICP
CPP : Cerebral Perfusion Pressure
MAP : Mean Arterial Pressure
ICP : Intra Cranial Pressure
CPP < 70 mmHg Iskemik Otak
Case 1
Mr. A is brought to A&E
Department via EMS with full C-
spine precaution. The patient
was state in multiple fracture
due to highway accident.
GCS: 8 with raccoon eyes sign;
BP: 160/90 mmHg; HR: 100x/m;
RR: 35x/m. Blood running from
his nose.
Source: Huizenga et al., 2009
Pengkajian (IGD)
¡ A
¡ B
¡ C
¡ D
Dx. Penunjang?
Protokol Khusus:
Resusitasi Otak
1.  IV: Normovolume
2.  Hiperventilasi
3.  Manitol 20%, 1 gr/kgBB
4.  Furosemide, 0.3-0.5 mg/kgBB
5.  Antikonvulsan
Indikasi Masuk ICU
1.  Tipes 1: Hypoxemia <50%
2.  Tipes 2: Hypercapnia >50%
Ventilator Settings
1.  RR 4-20x/m
2.  Tidal Volume 5-15cc/KgBB
3.  FiO2% 40-100%
4.  I:E Ratio 1:2 / 1:1.5
INDIKASI MASUK ICU
Mr. A has been on the ventilator for
24 hours after post craniotomy
surgery. You volunteered to care for
him today, since you know him from
the intubation yesterday.
The settings: PCMV 14, VT 700, PEEP 5
mmHg, FIO2 60%, I:E 1:2. Since 07:00,
RR 20x/m. On drugs. SaO2: 100%.
High pressure alarm (The time is now
11:00). Patient look uncomfortable
Source: Plambex, 2009
Drugs
1.  Sedatives: propofol
2.  Analgesics
3.  Paralytics / NMBs (Neuromuscular
Blocking agents: Norcuron
4.  Neuroleptics: Haldol
Pengkajian (ICU)
¡ A
¡ B
¡ C
¡ D
Dx. Penunjang?
ABG
¡ PaCO2 is 28, the pH is 7.48, and the
PaO2 is 120
¡ (normals: PaCO2 35-45 mm Hg, pH
7.35-7.45 mm Hg, PaO2 80-100 mm
Hg).
¡ Based on the ABG, the
pulmonologist changes the
vent settings to SIMV, rate 10,
PS 10, FIO2 40%. The VT remains
700, RR 24. How will these new
settings help Mr. Hill?
Weaning criteria
1.  TV: at least 5ml/Kg
2.  MV: less than 10l/m
3.  RR: less than 25x/m
4.  ABG
5.  Klinis
GOODLUCK!!

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